(Q53332784)

English

The leukemia-associated cytoplasmic nucleophosmin mutant is an oncogene with paradoxical functions: Arf inactivation and induction of cellular senescence.

scientific article published on 4 June 2007

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17546053%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

The leukemia-associated cytoplasmic nucleophosmin mutant is an oncogene with paradoxical functions: Arf inactivation and induction of cellular senescence (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17546053%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17546053%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

John G Clohessy

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17546053%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Paolo Sportoletti

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17546053%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

author name string

Cheng K

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17546053%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Grisendi S

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17546053%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Majid S

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17546053%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Pandolfi PP

7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17546053%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

language of work or name

0 references

publication date

4 June 2007

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17546053%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17546053%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

26

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17546053%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

53

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17546053%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

7391-7400

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17546053%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

https://scigraph.springernature.com/pub.10.1038/sj.onc.1210549

0 references

Myeloid leukemia-associated nucleophosmin mutants perturb p53-dependent and independent activities of the Arf tumor suppressor protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210549

21 January 2018

Activated H-ras rescues E1A-induced apoptosis and cooperates with E1A to overcome p53-dependent growth arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210549

21 January 2018

Expression of the retinoblastoma tumor suppressor gene (RB-1) in acute leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210549

21 January 2018

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210549

7 January 2021

based on heuristic

inferred from DOI database lookup

Recent lessons in gene expression, cell cycle control, and cell biology from adenovirus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210549

7 January 2021

based on heuristic

inferred from DOI database lookup

Nucleophosmin is required for DNA integrity and p19Arf protein stability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210549

7 January 2021

based on heuristic

inferred from DOI database lookup

Nucleophosmin regulates the stability and transcriptional activity of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210549

7 January 2021

based on heuristic

inferred from DOI database lookup

Delocalization and destabilization of the Arf tumor suppressor by the leukemia-associated NPM mutant

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210549

7 January 2021

based on heuristic

inferred from DOI database lookup

E1A signaling to p53 involves the p19(ARF) tumor suppressor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210549

7 January 2021

based on heuristic

inferred from DOI database lookup

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210549

7 January 2021

based on heuristic

inferred from DOI database lookup

Both carboxy-terminus NES motif and mutated tryptophan(s) are crucial for aberrant nuclear export of nucleophosmin leukemic mutants in NPMc+ AML.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210549

7 January 2021

based on heuristic

inferred from DOI database lookup

Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210549

7 January 2021

based on heuristic

inferred from DOI database lookup

New insights into the nucleophosmin/nucleoplasmin family of nuclear chaperones

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210549

7 January 2021

based on heuristic

inferred from DOI database lookup

Adenovirus E1A: remodelling the host cell, a life or death experience

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210549

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of nucleophosmin in embryonic development and tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210549

7 January 2021

based on heuristic

inferred from DOI database lookup

Nucleophosmin and cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210549

7 January 2021

based on heuristic

inferred from DOI database lookup

p300/MDM2 complexes participate in MDM2-mediated p53 degradation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210549

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification and characterization of nucleophosmin/B23/numatrin which binds the anti-oncogenic transcription factor IRF-1 and manifests oncogenic activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210549

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor suppressor genes in normal and malignant hematopoiesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210549

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210549

7 January 2021

based on heuristic

inferred from DOI database lookup

Nucleophosmin/B23 regulates transcriptional activation of E2F1 via modulating the promoter binding of NF-kappaB, E2F1 and pRB.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210549

7 January 2021

based on heuristic

inferred from DOI database lookup

Frequent loss of heterozygosity on chromosome 5 in non-small cell lung carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210549

7 January 2021

based on heuristic

inferred from DOI database lookup

Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210549

7 January 2021

based on heuristic

inferred from DOI database lookup

p19ARF links the tumour suppressor p53 to Ras

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210549

7 January 2021

based on heuristic

inferred from DOI database lookup

Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210549

7 January 2021

based on heuristic

inferred from DOI database lookup

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210549

7 January 2021

based on heuristic

inferred from DOI database lookup

Divorcing ARF and p53: an unsettled case

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210549

7 January 2021

based on heuristic

inferred from DOI database lookup

Prevalence and prognostic impact of NPM1 mutations in 1485 adult patients with acute myeloid leukemia (AML).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210549

7 January 2021

based on heuristic

inferred from DOI database lookup

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210549

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutations in nucleophosmin (NPM1) in acute myeloid leukemia (AML): association with other gene abnormalities and previously established gene expression signatures and their favorable prognostic significance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210549

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of p53 transactivation required for transformation by adenovirus early 1B protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210549

7 January 2021

based on heuristic

inferred from DOI database lookup

The targeting of the proteasomal regulatory subunit S2 by adenovirus E1A causes inhibition of proteasomal activity and increased p53 expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210549

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q53332784&oldid=1466411324"