(Q53334228)

13 May 2018

title

Loss of suppressor-of-fused function promotes tumorigenesis. (English)

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13 May 2018

author

Tom Curran

6

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13 May 2018

author name string

Y Lee

1

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13 May 2018

R Kawagoe

2

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13 May 2018

K Sasai

3

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13 May 2018

Y Li

4

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13 May 2018

H R Russell

5

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13 May 2018

P J McKinnon

7

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13 May 2018

language of work or name

English

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publication date

23 April 2007

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13 May 2018

published in

Oncogene

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13 May 2018

volume

26

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13 May 2018

issue

44

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13 May 2018

page(s)

6442-6447

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13 May 2018

https://scigraph.springernature.com/pub.10.1038/sj.onc.1210467

exact match

0 references

cites work

MIM/BEG4, a Sonic hedgehog-responsive gene that potentiates Gli-dependent transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210467

Mice deficient in the fused homolog do not exhibit phenotypes indicative of perturbed hedgehog signaling during embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210467

Suppressor of Fused represses Gli-mediated transcription by recruiting the SAP18-mSin3 corepressor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210467

Cardiac and CNS defects in a mouse with targeted disruption of suppressor of fused

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210467

The hedgehog pathway and neurological disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210467

REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210467

Characterization of the physical interaction of Gli proteins with SUFU proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210467

Hedgehog checkpoints in medulloblastoma: the chromosome 17p deletion paradigm.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210467

Altered neural cell fates and medulloblastoma in mouse patched mutants

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210467

Communicating with Hedgehogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210467

Tumor spectrum analysis in p53-mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210467

Gli1 is important for medulloblastoma formation in Ptc1+/- mice

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210467

The neuronal repressor REST/NRSF is an essential regulator in medulloblastoma cells.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210467

Patched2 modulates tumorigenesis in patched1 heterozygous mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210467

The Hedgehog response network: sensors, switches, and routers

21 January 2018

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Medulloblastoma: developmental mechanisms out of control

21 January 2018

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Loss of patched and disruption of granule cell development in a pre-neoplastic stage of medulloblastoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210467

The negative regulator of Gli, Suppressor of fused (Sufu), interacts with SAP18, Galectin3 and other nuclear proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210467

Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210467

Shh pathway activity is down-regulated in cultured medulloblastoma cells: implications for preclinical studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210467

Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210467

Mutations in SUFU predispose to medulloblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210467

Divergence of hedgehog signal transduction mechanism between Drosophila and mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210467

XRCC4 suppresses medulloblastomas with recurrent translocations in p53-deficient mice

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1038/SJ.ONC.1210467

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13 May 2018

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13 May 2018