(Q53351288)

13 May 2018

review article

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title

Short- and intermediate-term carcinogenicity testing--a review. Part 1: the prototypes mouse skin tumour assay and rat liver focus assay. (English)

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13 May 2018

author name string

Enzmann H

1

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13 May 2018

Bomhard E

2

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13 May 2018

Iatropoulos M

3

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13 May 2018

Ahr HJ

4

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13 May 2018

Schlueter G

5

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13 May 2018

Williams GM

6

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13 May 2018

publication date

1 November 1998

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13 May 2018

Food and Chemical Toxicology

published in

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13 May 2018

volume

36

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13 May 2018

issue

11

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13 May 2018

page(s)

979-995

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13 May 2018

Chemical cancerogenesis: definitions of frequently used terms.

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Age-, sex-, and strain-dependent differences in the induction of enzyme-altered islands in rat liver by diethylnitrosamine

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Multistage carcinogenesis in mouse skin

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Incorporation of bromodeoxyuridine in glutathione S-transferase-positive hepatocytes during rat multistage hepatocarcinogenesis

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An initiation-promotion assay in rat liver as a potential complement to the 2-year carcinogenesis bioassay

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Characterization of the promotion of altered hepatic foci by 2,3,7,8-tetrachlorodibenzo-p-dioxin in the female rat

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Potential significance of phenotypic heterogeneity of focal lesions at different stages in hepatocarcinogenesis.

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Non-persisting early foci of altered hepatocytes induced in rats by N-nitrosomorpholine

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Simple elementary method for the quantification of focal liver lesions induced by carcinogens.

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Effects of low doses of N-nitrosomorpholine on the development of early stages of hepatocarcinogenesis.

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Glycogen phosphorylase hyperactive foci of altered hepatocytes in aged rats

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THE INITIATING AND PROMOTING ELEMENTS IN TUMOR PRODUCTION : AN ANALYSIS OF THE EFFECTS OF TAR, BENZPYRENE, AND METHYLCHOLANTHRENE ON RABBIT SKIN.

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Malignant progression of papillomas induced by the initiation--promotion protocol in NMRI mouse skin.

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Tumor induction in initiated mouse skin by phorbol esters and methyl methanesulfonate: correlation between chromosomal damage and conversion ('stage I of tumor promotion') in vivo

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Effect of dietary vitamin E on the development of altered hepatic foci and hepatic tumors induced by the peroxisome proliferator ciprofibrate

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Comparison of target organs of carcinogenicity for mutagenic and non-mutagenic chemicals

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The natural history and dose-response characteristics of enzyme-altered foci in rat liver following phenobarbital and diethylnitrosamine administration

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Partial hepatectomy is a promoter of hepatocarcinogenesis in C57BL/6J male mice but not in C3H/HeJ male mice

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A reexamination of false-positive rates for carcinogenesis studies

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Use of statistical decision rules for evaluating laboratory animal carcinogenicity studies

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Correlations between chemically related site-specific carcinogenic effects in long-term studies in rats and mice

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The relationship between use of the maximum tolerated dose and study sensitivity for detecting rodent carcinogenicity.

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Urinary aflatoxin levels, hepatitis-B virus infection and hepatocellular carcinoma in Taiwan

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Accelerated rodent bioassay predictive of chemical carcinogenesis

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Advantages and limitations of stereological estimation of placental glutathione S-transferase-positive rat liver cell foci by computerized three-dimensional reconstruction.

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Use of rodent carcinogenicity test results for determining potential cancer risk to humans

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Pathological markers for non-genotoxic agent-associated carcinogenesis

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Medium-term rat liver bioassay for rapid detection of carcinogens and modifiers of hepatocarcinogenesis

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Rapid bioassay methods for carcinogens and modifiers of hepatocarcinogenesis

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Chromosomal aberrations as a contributing factor for tumor promotion in the mouse skin

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Suppression of the first stage of phorbol 12-tetradecanoate 13-acetate-effected tumor promotion in mouse skin by nontoxic inhibition of DNA synthesis

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Use of rat liver altered focus models for testing chemicals that have completed two-year carcinogenicity studies

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Liver carcinogenesis is not a predicted outcome of chemically induced hepatocyte proliferation

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Hepatocarcinogenesis in the rat: the effect of promoters and carcinogens in vivo and in vitro

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Lack of initiating and promoting activity of thiourea in rat liver foci bioassay

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Molecular genetics of thyroid and parathyroid neoplasia.

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Sequential Hepatic Histologic and Histochemical Changes Produced by Diethylnitrosamine in the Rhesus Monkey 2

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Cell proliferation and apoptosis in normal liver and preneoplastic foci

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Cell proliferation and renal carcinogenesis

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Hepatocellular carcinoma. A worldwide problem and the major risk factors

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SENCAR mouse skin tumorigenesis model versus other strains and stocks of mice

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New principle for the analysis of chemical carcinogenesis

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Sequential functional and morphological alterations during hepatocarcinogenesis induced in rats by feeding of a low dose of 2-acetylaminofluorene.

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A molecular approach to cancer risk

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Effects of liver-tumor promoters on phalloidin sensitivity of rat hepatocytes.

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Enzyme histochemical and morphological phenotype of amphophilic foci and amphophilic/tigroid cell adenomas in rat liver after combined treatment with dehydroepiandrosterone and N-nitrosomorpholine.

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Non-linearity of neoplastic conversion induced in rat liver by low exposures to diethylnitrosamine

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Chemical carcinogen mechanisms of action and implications for testing methodology

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Alterations in epidermal biochemistry as a consequence of stage-specific genetic changes in skin carcinogenesis

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Quantitative morphometric comparison between the expression of two different "marker enzymes" in preneoplastic liver lesions induced in rats with low doses of N-nitrosodiethanolamine

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7 January 2021

10.1016/S0278-6915(98)00063-5

Identifiers

DOI

1 reference

13 May 2018

1 reference

13 May 2018