(Q53354195)

13 May 2018

title

Chk1-cyclin A/Cdk1 axis regulates origin firing programs in mammals. (English)

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13 May 2018

author name string

Makoto Nakanishi

1

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13 May 2018

Yuko Katsuno

2

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13 May 2018

Hiroyuki Niida

3

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13 May 2018

Hiroshi Murakami

4

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13 May 2018

Midori Shimada

5

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13 May 2018

publication date

1 January 2010

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13 May 2018

published in

Chromosome Research

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13 May 2018

volume

18

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13 May 2018

issue

1

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13 May 2018

page(s)

103-113

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13 May 2018

https://scigraph.springernature.com/pub.10.1007/s10577-009-9086-2

exact match

0 references

cites work

Formation of nascent DNA molecules during inhibition of replicon initiation in mammalian cells

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https://api.crossref.org/works/10.1007%2FS10577-009-9086-2

Evidence that the ATR/Chk1 pathway maintains normal replication fork progression during unperturbed S phase.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10577-009-9086-2

ATR, Claspin and the Rad9-Rad1-Hus1 complex regulate Chk1 and Cdc25A in the absence of DNA damage

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10577-009-9086-2

Rapid destruction of human Cdc25A in response to DNA damage

21 January 2018

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12 December 2020

Construction of a cyclin D1-Cdk2 fusion protein to model the biological functions of cyclin D1-Cdk2 complexes

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In search of the holy replicator

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Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication.

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Human mutation rate associated with DNA replication timing

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Chk1 regulates the density of active replication origins during the vertebrate S phase.

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TopBP1 activates the ATR-ATRIP complex

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12 December 2020

Nuclear organization: uniting replication foci, chromatin domains and chromosome structure.

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12 December 2020

Rapid PIKK-dependent release of Chk1 from chromatin promotes the DNA-damage checkpoint response.

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12 December 2020

Chk1 is haploinsufficient for multiple functions critical to tumor suppression

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12 December 2020

A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome

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12 December 2020

Distinct activation pathways confer cyclin-binding specificity on Cdk1 and Cdk2 in human cells

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12 December 2020

Regulation of DNA replication by the S-phase DNA damage checkpoint

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12 December 2020

Specific role of Chk1 phosphorylations in cell survival and checkpoint activation

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12 December 2020

The DNA damage response: ten years after

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Temporal profile of replication of human chromosomes

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DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

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Ataxia-telangiectasia and the Nijmegen breakage syndrome: related disorders but genes apart

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Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin

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Differential roles for checkpoint kinases in DNA damage-dependent degradation of the Cdc25A protein phosphatase

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12 December 2020

Genome-wide localization of pre-RC sites and identification of replication origins in fission yeast

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12 December 2020

An essential role for Cdk1 in S phase control is revealed via chemical genetics in vertebrate cells

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12 December 2020

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

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12 December 2020

DNA damage checkpoints in mammals

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12 December 2020

Depletion of Chk1 leads to premature activation of Cdc2-cyclin B and mitotic catastrophe

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12 December 2020

Isolation and characterisation of a yeast chromosomal replicator

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12 December 2020

Regulation of cellular and SV40 virus origins of replication by Chk1-dependent intrinsic and UVC radiation-induced checkpoints

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12 December 2020

A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM

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CLB5-dependent activation of late replication origins in S. cerevisiae.

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12 December 2020

Chk2-deficient mice exhibit radioresistance and defective p53-mediated transcription

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12 December 2020

Genome-wide characterization of fission yeast DNA replication origins

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12 December 2020

Control of replication origin density and firing time in Xenopus egg extracts: role of a caffeine-sensitive, ATR-dependent checkpoint.

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12 December 2020

DNA replication. Choosing a place to begin

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12 December 2020

S-Cdk-dependent phosphorylation of Sld2 essential for chromosomal DNA replication in budding yeast

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12 December 2020

Chk1 is a histone H3 threonine 11 kinase that regulates DNA damage-induced transcriptional repression

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12 December 2020

Replication fork movement sets chromatin loop size and origin choice in mammalian cells

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12 December 2020

Replication of chromosomal and episomal DNA in X-ray-damaged human cells: a cis- or trans-acting mechanism?

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12 December 2020

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

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12 December 2020

Cdk1 and Cdk2 activity levels determine the efficiency of replication origin firing in Xenopus

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12 December 2020

Chk1 requirement for high global rates of replication fork progression during normal vertebrate S phase

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12 December 2020

Genomic mapping of single-stranded DNA in hydroxyurea-challenged yeasts identifies origins of replication

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Dormant origins licensed by excess Mcm2-7 are required for human cells to survive replicative stress.

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Right place, right time, and only once: replication initiation in metazoans

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12 December 2020

Interaction of Xenopus Cdc2 x cyclin A1 with the origin recognition complex.

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12 December 2020

CDK phosphorylation of Drc1 regulates DNA replication in fission yeast.

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12 December 2020

Cyclin A-Cdk1 regulates the origin firing program in mammalian cells

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12 December 2020

Excess Mcm2-7 license dormant origins of replication that can be used under conditions of replicative stress.

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12 December 2020

ATR and ATM regulate the timing of DNA replication origin firing

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12 December 2020

Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A.

1 reference

12 December 2020

Stable association of mitotic cyclin B/Cdc2 to replication origins prevents endoreduplication

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12 December 2020

Genome-wide replication profiles of S-phase checkpoint mutants reveal fragile sites in yeast

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12 December 2020

Inhibition of DNA replication by ionizing radiation is mediated by a trans-acting factor

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12 December 2020

Aberrant cell cycle checkpoint function and early embryonic death in Chk1(-/-) mice

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12 December 2020

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

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12 December 2020

10.1007/S10577-009-9086-2

Identifiers

DOI

1 reference

13 May 2018

PubMed ID

20013152

1 reference

13 May 2018