(Q53411432)

14 May 2018

review article

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title

[The JAK-STAT signaling pathway and its role in oncogenesis, immunomodulation and development]. (English)

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14 May 2018

author name string

R F Duarte

series ordinal

1

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14 May 2018

D A Frank

series ordinal

2

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14 May 2018

language of work or name

Spanish

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publication date

1 February 2000

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14 May 2018

published in

Medicina clínica

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14 May 2018

volume

114

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14 May 2018

page(s)

227-234

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14 May 2018

issue

6

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14 May 2018

Cytokine signaling through nonreceptor protein tyrosine kinases

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JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

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7 January 2021

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In vitro activation of Stat3 by epidermal growth factor receptor kinase

7 January 2021

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Src kinases and not JAKs activate STATs during IL-3 induced myeloid cell proliferation

7 January 2021

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JAKs and STATs branch out.

7 January 2021

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Requirement of serine phosphorylation for formation of STAT-promoter complexes

7 January 2021

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Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

7 January 2021

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7 January 2021

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Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling

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Functional interactions between Stat5 and the glucocorticoid receptor

7 January 2021

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Cross-talk between retinoic acid and interferons: molecular mechanisms of interaction in acute promyelocytic leukemia cells

7 January 2021

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The rapid inactivation of nuclear tyrosine phosphorylated Stat1 depends upon a protein tyrosine phosphatase.

7 January 2021

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Differential regulation of the alpha/beta interferon-stimulated Jak/Stat pathway by the SH2 domain-containing tyrosine phosphatase SHPTP1

7 January 2021

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Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals

7 January 2021

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A family of cytokine-inducible inhibitors of signalling

7 January 2021

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A new protein containing an SH2 domain that inhibits JAK kinases

7 January 2021

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Structure and function of a new STAT-induced STAT inhibitor

7 January 2021

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A nuclear protein tyrosine phosphatase is required for the inactivation of Stat1.

7 January 2021

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7 January 2021

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7 January 2021

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Transcription factor p91 interacts with the epidermal growth factor receptor and mediates activation of the c-fos gene promoter

7 January 2021

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Mammary gland factor (MGF) is a novel member of the cytokine regulated transcription factor gene family and confers the prolactin response.

7 January 2021

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Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathway.

7 January 2021

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Involvement of STAT3 in the granulocyte colony-stimulating factor-induced differentiation of myeloid cells

7 January 2021

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Regulation of T helper cell differentiation by STAT molecules.

7 January 2021

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TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

7 January 2021

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Defective TNF-alpha-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases

7 January 2021

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Signals through gp130 upregulate bcl-x gene expression via STAT1-binding cis-element in cardiac myocytes.

7 January 2021

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Interleukin-2 receptor gamma chain mutation results in X-linked severe combined immunodeficiency in humans

7 January 2021

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Defective lymphoid development in mice lacking Jak3

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

7 January 2021

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Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

7 January 2021

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B lymphocytes from patients with chronic lymphocytic leukemia contain signal transducer and activator of transcription (STAT) 1 and STAT3 constitutively phosphorylated on serine residues.

7 January 2021

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7 January 2021

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An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity.

7 January 2021

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Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein

7 January 2021

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Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl

7 January 2021

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Signal transducer and activator of transcription (STAT)5 activation by BCR/ABL is dependent on intact Src homology (SH)3 and SH2 domains of BCR/ABL and is required for leukemogenesis

7 January 2021

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Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides: tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines

7 January 2021

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Constitutively activated Jak-STAT pathway in T cells transformed with HTLV-I.

7 January 2021

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Proliferation of adult T cell leukemia/lymphoma cells is associated with the constitutive activation of JAK/STAT proteins

7 January 2021

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Interleukin 6 is essential for in vivo development of B lineage neoplasms

7 January 2021

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Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas

7 January 2021

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Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

7 January 2021

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Distinct tumorigenic potential of abl and raf in B cell neoplasia: abl activates the IL-6 signaling pathway

7 January 2021

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Thanatophoric dysplasia (types I and II) caused by distinct mutations in fibroblast growth factor receptor 3.

7 January 2021

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Activation of Stat1 by mutant fibroblast growth-factor receptor in thanatophoric dysplasia type II dwarfism

7 January 2021

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Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses

7 January 2021

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Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor

7 January 2021

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Interferon-gamma-mediated activation of STAT1alpha regulates growth factor-induced mitogenesis.

7 January 2021

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Suppression of interleukin-3-induced gene expression by a C-terminal truncated Stat5: role of Stat5 in proliferation.

7 January 2021

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Fludarabine-induced immunosuppression is associated with inhibition of STAT1 signaling

7 January 2021

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STATs and gene regulation

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0025-7753%2800%2971252-8

STATs: signal transducers and activators of transcription

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0025-7753%2800%2971252-8

Jaks and STATs: biological implications

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0025-7753%2800%2971252-8

Interleukin-6 and its receptor are expressed in human intestinal epithelial cells

7 January 2021

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0025-7753(00)71252-8

1 reference

14 May 2018

PubMed ID

10757107

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14 May 2018