(Q53416614)

14 May 2018

title

Does senna extract promote growth of aberrant crypt foci and malignant tumors in rat colon? (English)

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14 May 2018

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N Mascolo

1

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E Mereto

2

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F Borrelli

3

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P Orsi

4

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D Sini

5

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A A Izzo

6

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B Massa

7

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M Boggio

8

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F Capasso

9

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publication date

1 November 1999

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14 May 2018

Digestive Diseases and Sciences

published in

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14 May 2018

volume

44

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issue

11

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14 May 2018

page(s)

2226-2230

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14 May 2018

https://scigraph.springernature.com/pub.10.1023/a:1026696402212

exact match

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cites work

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Cassia senna inhibits mutagenic activities of benzo[a]-pyrene, aflatoxin B1, shamma and methyl methanesulfonate.

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Too many rodent carcinogens: mitogenesis increases mutagenesis

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A review of the genetic effects of naturally occurring flavonoids, anthraquinones and related compounds

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Role of aberrant crypt foci in understanding the pathogenesis of colon cancer

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Anthranoid laxative abuse--a risk for colorectal cancer?

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12 December 2020

Cell proliferation induced by laxatives and related compounds in the rat intestine.

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12 December 2020

Evaluation of the potential carcinogenic activity of Senna and Cascara glycosides for the rat colon

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12 December 2020

Genotoxicity in the hepatocyte/DNA repair test and toxicity to liver mitochondria of 1-hydroxyanthraquinone and several dihydroxyanthraquinones

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12 December 2020

Aberrant crypts correlate with tumor incidence in F344 rats treated with azoxymethane and phytate

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12 December 2020

Chronic sennoside treatment does not cause habituation and secondary hyperaldosteronism in rats

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12 December 2020

Investigations on DNA binding in rat liver and in Salmonella and on mutagenicity in the Ames test by emodin, a natural anthraquinone.

1 reference

12 December 2020

Vegetable purgatives containing anthracene derivatives. V. A third active glycoside of senna

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Use of azoxymethane-induced foci of aberrant crypts in rat colon to identify potential cancer chemopreventive agents.

1 reference

12 December 2020

Recent findings on the mode of action of laxatives: the role of platelet activating factor and nitric oxide

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Hydroxyanthraquinones as tumor promoters: enhancement of malignant transformation of C3H mouse fibroblasts and growth stimulation of primary rat hepatocytes

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Nitric oxide as a modulator of intestinal water and electrolyte transport

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12 December 2020

Genotoxicity of naturally occurring hydroxyanthraquinones.

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Anthranoid laxatives and colorectal cancer

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12 December 2020

The relative purgative activities of 1,8-dihydroxyanthracene derivatives.

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12 December 2020

Two-year carcinogenicity study with sennosides in the rat: emphasis on gastro-intestinal alterations

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12 December 2020

Sequential analyses of the growth and morphological characteristics of aberrant crypt foci: putative preneoplastic lesions

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12 December 2020

Carcinogenicity of naturally occurring 1-hydroxyanthraquinone in rats: induction of large bowel, liver and stomach neoplasms

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12 December 2020

Assessment of the genotoxic risk from laxative senna products

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12 December 2020

Adverse effects of laxatives: fact and fiction

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12 December 2020

Excessively high cell proliferation in sigmoid colon after an oral purge with anthraquinone glycosides

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12 December 2020

Ability of aberrant crypt foci characteristics to predict colonic tumor incidence in rats fed cholic acid.

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1026696402212

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14 May 2018

Dimensions Publication ID

1021294115

0 references

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14 May 2018