(Q53419011)

14 May 2018

title

Cyclooxygenase knockout mice: models for elucidating isoform-specific functions. (English)

1 reference

14 May 2018

0 references

Langenbach R

1

1 reference

14 May 2018

Loftin C

series ordinal

2

1 reference

14 May 2018

Lee C

series ordinal

3

1 reference

14 May 2018

Tiano H

series ordinal

4

1 reference

14 May 2018

language of work or name

English

0 references

publication date

1 October 1999

1 reference

14 May 2018

published in

Biochemical Pharmacology

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14 May 2018

volume

58

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14 May 2018

issue

8

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14 May 2018

page(s)

1237-1246

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14 May 2018

Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence

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Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing

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Differentiation of monocytoid THP-1 cells with phorbol ester induces expression of prostaglandin endoperoxide synthase-1 (COX-1).

7 January 2021

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Effects of transforming growth factor beta and interleukin-1 beta on expression of cyclooxygenase 1 and 2 and phospholipase A2 mRNA in lung fibroblasts and endothelial cells in culture

7 January 2021

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Selective Induction of Prostaglandin G/H Synthase I by Stem Cell Factor and Dexamethasone in Mast Cells

7 January 2021

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Prostacyclin synthesis in ovine pulmonary artery is developmentally regulated by changes in cyclooxygenase-1 gene expression

7 January 2021

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Expression of a mitogen-inducible cyclooxygenase in brain neurons: regulation by synaptic activity and glucocorticoids

7 January 2021

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Constitutive expression of prostaglandin endoperoxide G/H synthetase (PGHS)-2 but not PGHS-1 in hum an tracheal epithelial cells in vitro

7 January 2021

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Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction

7 January 2021

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Different intracellular locations for prostaglandin endoperoxide H synthase-1 and -2.

7 January 2021

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Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and -2

7 January 2021

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Molecular mechanisms of diverse actions of prostanoid receptors

7 January 2021

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Differential activation of adipogenesis by multiple PPAR isoforms.

7 January 2021

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Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma

7 January 2021

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Prostaglandin synthase-1 and prostaglandin synthase-2 are coupled to distinct phospholipases for the generation of prostaglandin D2 in activated mast cells

7 January 2021

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Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs

7 January 2021

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7 January 2021

Towards a better aspirin

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Induction of cyclo-oxygenase-2 by cytokines in human pulmonary epithelial cells: regulation by dexamethasone

7 January 2021

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Cyclooxygenase-2 inhibitors: a new class of anti-inflammatory agents that spare the gastrointestinal tract

7 January 2021

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Aspirin-like molecules that covalently inactivate cyclooxygenase-2.

7 January 2021

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Mechanism of action of nonsteroidal anti-inflammatory drugs

7 January 2021

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Pharmacological analysis of cyclooxygenase-1 in inflammation

7 January 2021

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The mechanisms of action of nonsteroidal antiinflammatory drugs

7 January 2021

1 reference

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Effects of nonsteroidal anti-inflammatory drugs on proliferation and on induction of apoptosis in colon cancer cells by a prostaglandin-independent pathway.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse.

7 January 2021

1 reference

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Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II.

7 January 2021

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Self-promotion? Intimate connections between APC and prostaglandin H synthase-2.

7 January 2021

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Prostaglandin synthase 2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Cyclooxygenase-2: regulation and relevance in inflammation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Nonsteroidal anti-inflammatory drugs and gastroenteropathy: the second hundred years

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Disruption of cyclooxygenase genes in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Renal toxicity of non-steroidal anti-inflammatory drugs.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Nonsteroidal antiinflammatory drugs and the gastrointestinal tract. The double-edged sword

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Renal toxicity of the nonsteroidal anti-inflammatory drugs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Distinct isoforms (COX-1 and COX-2) of cyclooxygenase: possible physiological and therapeutic implications

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Role of prostaglandins in gastroduodenal mucosal protection.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Renal effects of over-the-counter analgesics.

7 January 2021

1 reference

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Aspirin use and reduced risk of fatal colon cancer

7 January 2021

1 reference

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A hypothesis: nonsteroidal anti-inflammatory drugs reduce the incidence of large-bowel cancer.

7 January 2021

1 reference

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Eicosanoids and multistage carcinogenesis in NMRI mouse skin: role of prostaglandins E and F in conversion (first stage of tumor promotion) and promotion (second stage of tumor promotion).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Differential expression of prostaglandin H synthase isozymes during multistage carcinogenesis in mouse epidermis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Increased cyclooxygenase-2 levels in carcinogen-induced rat colonic tumors

7 January 2021

1 reference

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Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)

7 January 2021

1 reference

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Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene

7 January 2021

1 reference

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A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Inhibitory effect of aspirin on azoxymethane-induced colon carcinogenesis in F344 rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Cancer chemopreventive activity of resveratrol, a natural product derived from grapes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Localization of prostaglandin H synthase isoenzymes in murine epidermal tumors: suppression of skin tumor promotion by inhibition of prostaglandin H synthase-2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Cyclooxygenase regulates angiogenesis induced by colon cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Tumorigenic transformation of immortalized ECV endothelial cells by cyclooxygenase-1 overexpression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Multiple female reproductive failures in cyclooxygenase 2-deficient mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Sounding the alarm--does induction of prostaglandin endoperoxide synthase-2 control the mammalian ovulatory clock?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Prostaglandins and reproduction--what do knockouts really tell us?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Anovulation in cyclooxygenase-2-deficient mice is restored by prostaglandin E2 and interleukin-1beta

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Opposing actions of prostaglandins and oxytocin determine the onset of murine labor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Failure of parturition in mice lacking the prostaglandin F receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Multiple controls in inflammation. Extracellular and intracellular phospholipase A2, inducible and constitutive cyclooxygenase, and inducible nitric oxide synthase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Pharmacology of interleukin-1-induced neutrophil migration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Selective inhibition of NS-398 on prostanoid production in inflamed tissue in rat carrageenan-air-pouch inflammation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Cyclooxygenase 1 contributes to inflammatory responses in rats and mice: implications for gastrointestinal toxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Induction of cyclooxygenase 2 in gastric mucosal lesions and its inhibition by the specific antagonist delays healing in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Leukocyte lipid body formation and eicosanoid generation: cyclooxygenase-independent inhibition by aspirin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Biosynthesis and Role of the Endothelium‐Derived Vasodilator, Nitric Oxide, in the Gastric Mucosa

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Mechanisms of NSAID-induced gastroenteropathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Importance of gastric acid in gastric ulcer formation in rabbits with antibody-induced prostaglandin deficiency

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Characteristic morphology of the constricted fetal ductus arteriosus following maternal administration of indomethacin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Effect of advancing gestational age on the frequency of fetal ductal constriction in association with maternal indomethacin use.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

The prostaglandin receptor EP4 triggers remodelling of the cardiovascular system at birth.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Patent ductus arteriosus and neonatal death in prostaglandin receptor EP4-deficient mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Bleeding disorder due to platelet prostaglandin H synthase-1 (PGHS-1) deficiency

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Conditional gene targeting

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Non-steroidal anti-inflammatory drugs: how do they damage the gut?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Prostaglandin endoperoxide H synthases-1 and -2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

Do NSAIDs exert their colon cancer chemoprevention activities through the inhibition of mucosal prostaglandin synthetase?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

inferred from DOI database lookup

7 January 2021

based on heuristic

The function and mechanism of promoters of carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900158-6

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0006-2952(99)00158-6

1 reference

14 May 2018

release_7iqb3butzrhu7cziaxejvdobxi

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/7iqb3butzrhu7cziaxejvdobxi

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

14 May 2018