(Q53445619)

English

Enhanced sensitivity to tumor growth and development in multistage skin carcinogenesis by transforming growth factor-alpha-induced epidermal growth factor receptor activation but not p53 inactivation.

scientific article published in March 1997

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scholarly article

1 reference

Europe PubMed Central

14 May 2018

http://europepmc.org/abstract/MED/9115586

Enhanced sensitivity to tumor growth and development in multistage skin carcinogenesis by transforming growth factor-alpha-induced epidermal growth factor receptor activation but not p53 inactivation. (English)

1 reference

Europe PubMed Central

14 May 2018

http://europepmc.org/abstract/MED/9115586

1 reference

based on heuristic

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author name string

Shibata MA

1

1 reference

Europe PubMed Central

14 May 2018

http://europepmc.org/abstract/MED/9115586

Ward JM

2

1 reference

Europe PubMed Central

14 May 2018

http://europepmc.org/abstract/MED/9115586

Green JE

3

1 reference

Europe PubMed Central

14 May 2018

http://europepmc.org/abstract/MED/9115586

Merlino G

4

1 reference

Europe PubMed Central

14 May 2018

http://europepmc.org/abstract/MED/9115586

publication date

1 March 1997

1 reference

Europe PubMed Central

14 May 2018

http://europepmc.org/abstract/MED/9115586

Molecular Carcinogenesis

1 reference

Europe PubMed Central

14 May 2018

http://europepmc.org/abstract/MED/9115586

18

1 reference

Europe PubMed Central

14 May 2018

http://europepmc.org/abstract/MED/9115586

3

1 reference

Europe PubMed Central

14 May 2018

http://europepmc.org/abstract/MED/9115586

160-170

1 reference

Europe PubMed Central

14 May 2018

http://europepmc.org/abstract/MED/9115586

Rat Transforming Growth Factor Type 1: Structure and Relation to Epidermal Growth Factor

1 reference

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21 January 2018

Transmembrane TGF-alpha precursors activate EGF/TGF-alpha receptors.

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The erbB gene of avian erythroblastosis virus is a member of the src gene family

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21 January 2018

Multistage carcinogenesis in mouse skin

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21 January 2018

TGF alpha stimulates growth of skin papillomas by autocrine and paracrine mechanisms but does not cause neoplastic progression

1 reference

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21 January 2018

TGF alpha overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas

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21 January 2018

Hypertrophic gastropathy resembling Ménétrier's disease in transgenic mice overexpressing transforming growth factor alpha in the stomach

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21 January 2018

Transforming growth factor alpha dramatically enhances oncogene-induced carcinogenesis in transgenic mouse pancreas and liver

1 reference

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21 January 2018

Transgenic overexpression of transforming growth factor alpha bypasses the need for c-Ha-ras mutations in mouse skin tumorigenesis

1 reference

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21 January 2018

Rapid development of hepatic tumors in transforming growth factor alpha transgenic mice associated with increased cell proliferation in precancerous hepatocellular lesions initiated by N-nitrosodiethylamine and promoted by phenobarbital

1 reference

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21 January 2018

Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis

1 reference

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21 January 2018

Mutagenesis of the Ha-ras oncogene in mouse skin tumors induced by polycyclic aromatic hydrocarbons

1 reference

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21 January 2018

An activated Harvey ras oncogene produces benign tumours on mouse epidermal tissue

1 reference

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21 January 2018

Transfection of the EJ rasHa gene into keratinocytes derived from carcinogen-induced mouse papillomas causes malignant progression

1 reference

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21 January 2018

Altered regulation of TGF-beta 1 and TGF-alpha in primary keratinocytes and papillomas expressing v-Ha-ras

1 reference

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21 January 2018

Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction

1 reference

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21 January 2018

Progressive dysplasia and aneuploidy are hallmarks of mouse skin papillomas: relevance to malignancy

1 reference

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21 January 2018

Expression and characterization of transforming growth factor alpha precursor protein in transfected mammalian cells

1 reference

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21 January 2018

Cell-cell adhesion mediated by binding of membrane-anchored transforming growth factor alpha to epidermal growth factor receptors promotes cell proliferation

1 reference

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21 January 2018

Mutant p53 can induce tumorigenic conversion of human bronchial epithelial cells and reduce their responsiveness to a negative growth factor, transforming growth factor beta 1

1 reference

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21 January 2018

Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors.

1 reference

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21 January 2018

Positive immunohistochemical staining of p53 and cyclin D in advanced mouse skin tumors, but not in precancerous lesions produced by benzo[a]pyrene

1 reference

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21 January 2018

Benzo[a]pyrene-induced murine skin tumors exhibit frequent and characteristic G to T mutations in the p53 gene

1 reference

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21 January 2018

The TGF-alpha precursor expressed on the cell surface binds to the EGF receptor on adjacent cells, leading to signal transduction

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21 January 2018

Regulation of the epidermal growth factor receptor by phosphorylation

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21 January 2018

Evidence for autocrine/paracrine growth stimulation by transforming growth factor-alpha during the process of skin tumor promotion

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21 January 2018

Development of mammary hyperplasia and neoplasia in MMTV-TGF alpha transgenic mice

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Overexpression of TGFα in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast

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21 January 2018

Epidermal expression of transforming growth factor-alpha in transgenic mice: induction of spontaneous and 12-O-tetradecanoylphorbol-13-acetate-induced papillomas via a mechanism independent of Ha-ras activation or overexpression

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21 January 2018

Altered expression of the epidermal growth factor receptor and transforming growth factor-alpha during multistage skin carcinogenesis in SENCAR mice

1 reference

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21 January 2018

Identifiers

10.1002/(SICI)1098-2744(199703)18:3<160::AID-MC5>3.0.CO;2-J

1 reference

Europe PubMed Central

14 May 2018

http://europepmc.org/abstract/MED/9115586

1 reference

Europe PubMed Central

14 May 2018

http://europepmc.org/abstract/MED/9115586

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