(Q53467796)

14 May 2018

title

Frequency and spectrum of p53 mutations in gastric cancer--a molecular genetic and immunohistochemical study. (English)

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14 May 2018

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C Poremba

1

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14 May 2018

D W Yandell

2

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14 May 2018

Q Huang

3

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14 May 2018

J B Little

4

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14 May 2018

W Mellin

5

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14 May 2018

K W Schmid

6

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14 May 2018

W Böcker

7

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14 May 2018

B Dockhorn-Dworniczak

8

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14 May 2018

publication date

1 January 1995

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14 May 2018

published in

Virchows Archiv

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14 May 2018

volume

426

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14 May 2018

issue

5

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14 May 2018

page(s)

447-455

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14 May 2018

https://scigraph.springernature.com/pub.10.1007/bf00193167

exact match

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cites work

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p53 gene mutations and protein accumulation in human ovarian cancer

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The p53 tumour suppressor gene

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The molecular genetics of cancer

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Gastric cancer with p53 overexpression has high potential for metastasising to lymph nodes

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p53 gene mutations in human gastric cancer: wild-type p53 but not mutant p53 suppresses growth of human gastric cancer cells

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p53 expression and prognosis in gastric carcinoma

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12 December 2020

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12 December 2020

Mutations in the p53 gene occur in diverse human tumour types

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The two histological main types of gastric carcinoma: diffuse and so called intestinal-type carcinoma: an attempt at a histo-clinical classification

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A human gastric carcinoma contains a single mutated and an amplified normal allele of the Ki-ras oncogene

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Primary structure polymorphism at amino acid residue 72 of human p53.

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Molecular basis of base substitution hotspots in Escherichia coli

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Correlation of metabolic stability and altered quaternary structure of oncoprotein p53 with cell transformation

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Genetic alterations of the c-erbB-2 oncogene occur frequently in tubular adenocarcinoma of the stomach and are often accompanied by amplification of the v-erbA homologue

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Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life

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12 December 2020

P53 mutations in gastric carcinomas

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12 December 2020

Base transitions are the most frequent genetic changes at P53 in gastric cancer

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12 December 2020

p53 point mutations in primary human gastric carcinomas

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The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

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ras oncogenes in human cancer: a review

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Mutation spectrum of the p53 gene in bone and soft tissue sarcomas

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p53 mutations in colorectal cancer

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Human gastric carcinogenesis: a multistep and multifactorial process--First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention

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Somatic mutation of the APC gene in gastric cancer: frequent mutations in very well differentiated adenocarcinoma and signet-ring cell carcinoma

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12 December 2020

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p53 mutations in ovarian tumors, detected by temperature-gradient gel electrophoresis, direct sequencing and immunohistochemistry

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12 December 2020

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5-Methylcytosine as an Endogenous Mutagen in the Human LDL Receptor and p53 Genes

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Tumor suppressor p53: analysis of wild-type and mutant p53 complexes

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12 December 2020

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12 December 2020

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12 December 2020

The CpG dinucleotide and human genetic disease

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12 December 2020

Expression of p53 protein in normal, dysplastic, and malignant gastric mucosa: an immunohistochemical study

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12 December 2020

Identifiers

DOI

10.1007/BF00193167

1 reference

14 May 2018

PubMed ID

7633655

1 reference

14 May 2018