(Q53475750)

English

Rapid DNA degradation in primary rat hepatocytes treated with diverse cytotoxic chemicals: analysis by pulsed field gel electrophoresis and implications for alkaline elution assays.

scientific article published in January 1994

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1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/7957122

Rapid DNA degradation in primary rat hepatocytes treated with diverse cytotoxic chemicals: analysis by pulsed field gel electrophoresis and implications for alkaline elution assays. (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/7957122

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author name string

Elia MC

1

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/7957122

Storer RD

2

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/7957122

McKelvey TW

3

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/7957122

Kraynak AR

4

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/7957122

Barnum JE

5

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/7957122

Harmon LS

6

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/7957122

DeLuca JG

7

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/7957122

Nichols WW

8

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/7957122

publication date

1 January 1994

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/7957122

Environmental and Molecular Mutagenesis

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Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/7957122

24

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/7957122

3

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/7957122

181-191

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/7957122

Cytotoxicity as measured by trypan blue as a potentially confounding variable in the in vitro alkaline elution/rat hepatocyte assay

1 reference

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The single cell gel electrophoresis assay (comet assay): A European review

1 reference

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International Commission for Protection Against Environmental Mutagens and Carcinogens. Genotoxicity under extreme culture conditions. A report from ICPEMC Task Group 9.

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21 January 2018

Evaluation of the alkaline elution/rat hepatocyte assay as a predictor of carcinogenic/mutagenic potential

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21 January 2018

Endonuclease activation during apoptosis: the role of cytosolic Ca2+ and pH.

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Relationships among cytotoxicity, lysosomal breakdown, chromosome aberrations, and DNA double-strand breaks

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Implications of treatment-condition-induced genotoxicity for chemical screening and data interpretation

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A protocol and guide for the in vivo rat hepatocyte DNA-repair assay

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Perspective on the usefulness of the mouse lymphoma assay as an indicator of a genotoxic carcinogen: ten compounds which are positive in the mouse lymphoma assay but are not genotoxic carcinogens

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The role of the nucleus and other compartments in toxic cell death produced by alkylating hepatotoxicants

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Apoptosis: a product of programmed and unprogrammed cell death

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Application of programmable, autonomously controlled electrode (PACE) technology to the development of an improved pulsed field gel electrophoresis assay for DNA double-strand breaks in mammalian cells

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Significance and measurement of DNA double strand breaks in mammalian cells

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Cell death induced in a murine mastocytoma by 42-47 degrees C heating in vitro: evidence that the form of death changes from apoptosis to necrosis above a critical heat load.

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The calcium dependent endonuclease activity of isolated nuclear preparations. Relationships between its occurrence and the occurrence of other classes of enzymes found in nuclear preparations

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Comparison of cell death and adenosine triphosphate content as indicators of acute toxicity in vitro

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Principles and practice of DNA filter elution

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Dose-dependent induction of apoptosis in human tumour cell lines by widely diverging stimuli.

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DNA double-strand breaks in mutagenesis

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Apoptosis as a mechanism of tributyltin cytotoxicity to thymocytes: relationship of apoptotic markers to biochemical and cellular effects

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Early loss of large genomic DNA in vivo with accumulation of Ca2+ in the nucleus during acetaminophen-induced liver injury

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Acetaminophen-induced cytotoxicity in cultured mouse hepatocytes: effects of Ca(2+)-endonuclease, DNA repair, and glutathione depletion inhibitors on DNA fragmentation and cell death

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The single cell gel (SCG) assay: an electrophoretic technique for the detection of DNA damage in individual cells

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Identifiers

10.1002/EM.2850240307

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/7957122

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/7957122

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