(Q53480322)

English

Computer-aided design and synthesis of tetra-aryl-substituted alkenes and their bioevaluation as a selective modulator of estrogen-related receptor γ.

scientific article published on 5 February 2010

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scholarly article

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Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/20135221

Computer-aided design and synthesis of tetra-aryl-substituted alkenes and their bioevaluation as a selective modulator of estrogen-related receptor γ. (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/20135221

computer-aided design

1 reference

based on heuristic

inferred from title

author name string

Minseob Koh

1

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/20135221

Seung Bum Park

2

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/20135221

publication date

5 February 2010

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/20135221

Molecular Diversity

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/20135221

15

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/20135221

1

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/20135221

69-81

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/20135221

Isolation of a gene encoding a novel member of the nuclear receptor superfamily from the critical region of Usher syndrome type IIa at 1q41

1 reference

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Hormone-independent transcriptional activation and coactivator binding by novel orphan nuclear receptor ERR3

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Human ERRgamma, a third member of the estrogen receptor-related receptor (ERR) subfamily of orphan nuclear receptors: tissue-specific isoforms are expressed during development and in the adult

1 reference

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ERRgamma directs and maintains the transition to oxidative metabolism in the postnatal heart.

1 reference

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Expression and functional study of estrogen receptor-related receptors in human prostatic cells and tissues

1 reference

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Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRalpha and gamma.

1 reference

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21 January 2018

ERRgamma suppresses cell proliferation and tumor growth of androgen-sensitive and androgen-insensitive prostate cancer cells and its implication as a therapeutic target for prostate cancer.

1 reference

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21 January 2018

Estrogen receptor-related receptors: orphan receptors desperately seeking a ligand

1 reference

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21 January 2018

To ERR in the estrogen pathway

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21 January 2018

Structure-guided synthesis of tamoxifen analogs with improved selectivity for the orphan ERRgamma

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Efficient discovery of selective small molecule agonists of estrogen-related receptor gamma using combinatorial approach.

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Structure-based design of molecular cancer therapeutics

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Structure-based drug design: from nucleic acid to membrane protein targets

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Antibacterial drug discovery and structure-based design

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Simple and efficient production of (Z)-4-hydroxytamoxifen, a potent estrogen receptor modulator

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Structural basis for the deactivation of the estrogen-related receptor gamma by diethylstilbestrol or 4-hydroxytamoxifen and determinants of selectivity

1 reference

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21 January 2018

X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation

1 reference

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21 January 2018

Tamoxifen: toxicities and drug resistance during the treatment and prevention of breast cancer

1 reference

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21 January 2018

Cis-trans isomerization of organic molecules and biomolecules: implications and applications

1 reference

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21 January 2018

Metabolism of tamoxifen by recombinant human cytochrome P450 enzymes: formation of the 4-hydroxy, 4'-hydroxy and N-desmethyl metabolites and isomerization of trans-4-hydroxytamoxifen.

1 reference

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21 January 2018

Elimination of antiestrogenic effects of active tamoxifen metabolites by glucuronidation

1 reference

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21 January 2018

Tamoxifen antiestrogens. A comparison of the activity, pharmacokinetics, and metabolic activation of the cis and trans isomers of tamoxifen.

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21 January 2018

CHARMM: A program for macromolecular energy, minimization, and dynamics calculations

1 reference

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A synthetic method for formyl→ethynyl conversion (RCHO→RCCH or RCCR′)

1 reference

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21 January 2018

Bioactivities, estrogen receptor interactions, and plasminogen activator-inducing activities of tamoxifen and hydroxy-tamoxifen isomers in MCF-7 human breast cancer cells.

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptor coactivator-1alpha (PGC-1alpha) coactivates the cardiac-enriched nuclear receptors estrogen-related receptor-alpha and -gamma. Identification of novel leucine-rich interaction motif within PGC-1alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/20135221

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen-related receptor alpha and estrogen-related receptor gamma associate with unfavorable and favorable biomarkers, respectively, in human breast cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20135221

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11030-010-9224-Y

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/20135221

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/20135221

ResearchGate publication ID

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