(Q53500309)

English

AMP-activated protein kinase inhibits transforming growth factor-beta-induced Smad3-dependent transcription and myofibroblast transdifferentiation.

scientific article published on 4 February 2008

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/18250161

AMP-activated protein kinase inhibits transforming growth factor-beta-induced Smad3-dependent transcription and myofibroblast transdifferentiation. (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/18250161

4

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/18250161

5

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/18250161

author name string

Rangnath Mishra

1

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/18250161

Barbara L Cool

2

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/18250161

Keith R Laderoute

3

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/18250161

Michael S Simonson

6

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/18250161

language of work or name

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publication date

4 February 2008

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Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/18250161

number of pages

9

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based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/18250161

283

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Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/18250161

16

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/18250161

10461-10469

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/18250161

Myofibroblasts and mechano-regulation of connective tissue remodelling

1 reference

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21 January 2018

Myofibroblasts: molecular crossdressers.

1 reference

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The myofibroblast: one function, multiple origins

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Phenotypic transitions and fibrosis in diabetic nephropathy

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Interstitial fluid flow induces myofibroblast differentiation and collagen alignment in vitro.

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The fibronectin domain ED-A is crucial for myofibroblastic phenotype induction by transforming growth factor-beta1.

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Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts

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21 January 2018

TGF-beta signaling and the fibrotic response

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21 January 2018

Activation of AMP-activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders

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AMP-activated protein kinase--development of the energy sensor concept.

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AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism

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The AMP-activated/SNF1 protein kinase subfamily: metabolic sensors of the eukaryotic cell?

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AMP-activated protein kinase: an ultrasensitive system for monitoring cellular energy charge.

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Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells.

1 reference

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21 January 2018

The Ca2+/calmodulin-dependent protein kinase kinases are AMP-activated protein kinase kinases

1 reference

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21 January 2018

Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase

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21 January 2018

The adipocyte-secreted protein Acrp30 enhances hepatic insulin action

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Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome

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Cell cycle signaling by endothelin-1 requires Src nonreceptor protein tyrosine kinase

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21 January 2018

5'-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments

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21 January 2018

TGF-beta-regulated collagen type I accumulation: role of Src-based signals.

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21 January 2018

A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle

1 reference

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21 January 2018

Short-term overexpression of a constitutively active form of AMP-activated protein kinase in the liver leads to mild hypoglycemia and fatty liver

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800902200

21 January 2018

AMP-activated protein kinase (AMPK) signaling in endothelial cells is essential for angiogenesis in response to hypoxic stress

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800902200

21 January 2018

Concomitant loss of cell surface fibronectin and laminin from transformed rat kidney cells

1 reference

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21 January 2018

Renal fibrosis: collagen composition and assembly regulates epithelial-mesenchymal transdifferentiation

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21 January 2018

Voltage-insensitive Ca2+ channels and Ca2+/calmodulin-dependent protein kinases propagate signals from endothelin-1 receptors to the c-fos promoter

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21 January 2018

Endothelium-specific ablation of PDGFB leads to pericyte loss and glomerular, cardiac and placental abnormalities

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21 January 2018

Hepatocyte growth factor antagonizes the profibrotic action of TGF-beta1 in mesangial cells by stabilizing Smad transcriptional corepressor TGIF

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800902200

21 January 2018

Pioglitazone attenuates TGF-beta(1)-induction of fibronectin synthesis and its splicing variant in human mesangial cells via activation of peroxisome proliferator-activated receptor (PPAR)gamma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800902200

21 January 2018

Transcription factor Ets-1 is essential for mesangial matrix remodeling

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21 January 2018

Extracellular matrix metabolism in diabetic nephropathy

1 reference

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21 January 2018

Identification of a novel AMP-activated protein kinase beta subunit isoform that is highly expressed in skeletal muscle

1 reference

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21 January 2018

Smad3: a key player in pathogenetic mechanisms dependent on TGF-beta

1 reference

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21 January 2018

Smad3 as a mediator of the fibrotic response

1 reference

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21 January 2018

Immunomodulator FTY720 induces myofibroblast differentiation via the lysophospholipid receptor S1P3 and Smad3 signaling

1 reference

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21 January 2018

Myofibroblast transdifferentiation in obliterative bronchiolitis: tgf-beta signaling through smad3-dependent and -independent pathways

1 reference

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21 January 2018

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

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21 January 2018

Human Smad3 and Smad4 are sequence-specific transcription activators

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AMP-activated protein kinase: greater AMP dependence, and preferential nuclear localization, of complexes containing the alpha2 isoform.

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Leptin stimulates fatty acid oxidation and peroxisome proliferator-activated receptor alpha gene expression in mouse C2C12 myoblasts by changing the subcellular localization of the alpha2 form of AMP-activated protein kinase

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Mammalian TAK1 activates Snf1 protein kinase in yeast and phosphorylates AMP-activated protein kinase in vitro

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Involvement of transforming growth factor-beta 1 signaling in hypoxia-induced tolerance to glucose starvation

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AMP-activated protein kinase induces a p53-dependent metabolic checkpoint

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The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

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The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis

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Inhibition of germline proliferation during C. elegans dauer development requires PTEN, LKB1 and AMPK signalling

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The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for smad3 in TGF-beta-induced transcriptional activation

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The steroid receptor co-activator-1 (SRC-1) potentiates TGF-beta/Smad signaling: role of p300/CBP.

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The Myofibroblast Is the Predominant Plasminogen Activator Inhibitor-1-Expressing Cell Type in Human Breast Carcinomas

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A mutant, noninhibitory plasminogen activator inhibitor type 1 decreases matrix accumulation in experimental glomerulonephritis

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Identifiers

10.1074/JBC.M800902200

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/18250161

release_gcc6cte3tff4xk65hamh6syeqe

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https://api.fatcat.wiki/v0/release/gcc6cte3tff4xk65hamh6syeqe

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/18250161

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