(Q53538486)

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EGFR mutants found in non-small cell lung cancer show different levels of sensitivity to suppression of Src: implications in targeting therapy.

scientific article published on 23 July 2007

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scholarly article

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2 January 2020

EGFR mutants found in non-small cell lung cancer show different levels of sensitivity to suppression of Src: implications in targeting therapy (English)

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2 January 2020

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2 January 2020

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Y-N Fu

1

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2 January 2020

C-L Yeh

2

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2 January 2020

H H-Y Cheng

3

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2 January 2020

C-H Yang

4

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2 January 2020

S-F Tsai

5

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2 January 2020

S-F Huang

6

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2 January 2020

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23 July 2007

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2 January 2020

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2 January 2020

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2 January 2020

957-965

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2 January 2020

https://scigraph.springernature.com/pub.10.1038/sj.onc.1210684

0 references

Tyrosine kinase signalling in breast cancer: epidermal growth factor receptor and c-Src interactions in breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210684

21 January 2018

c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210684

21 January 2018

An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors

1 reference

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21 January 2018

Distinctive activation patterns in constitutively active and gefitinib-sensitive EGFR mutants

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210684

21 January 2018

Mutation in the tyrosine kinase domain of epidermal growth factor receptor is a predictive and prognostic factor for gefitinib treatment in patients with non-small cell lung cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210684

21 January 2018

EGF-ERBB signalling: towards the systems level

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210684

21 January 2018

Mutations and addiction to EGFR: the Achilles 'heal' of lung cancers?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210684

21 January 2018

Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

1 reference

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21 January 2018

High frequency of epidermal growth factor receptor mutations with complex patterns in non-small cell lung cancers related to gefitinib responsiveness in Taiwan

1 reference

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21 January 2018

c-Src and cooperating partners in human cancer

1 reference

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21 January 2018

EGFR mutation and resistance of non-small-cell lung cancer to gefitinib

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210684

21 January 2018

Mutations of the epidermal growth factor receptor gene in lung cancer: biological and clinical implications.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210684

21 January 2018

Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210684

21 January 2018

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210684

21 January 2018

Phase I pharmacokinetic trial of the selective oral epidermal growth factor receptor tyrosine kinase inhibitor gefitinib ('Iressa', ZD1839) in Japanese patients with solid malignant tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210684

21 January 2018

EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210684

21 January 2018

EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210684

21 January 2018

Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210684

21 January 2018

Somatic mutations of the HER2 kinase domain in lung adenocarcinomas.

1 reference

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21 January 2018

Dasatinib (BMS-354825) selectively induces apoptosis in lung cancer cells dependent on epidermal growth factor receptor signaling for survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210684

21 January 2018

Structure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210684

21 January 2018

Src phosphorylation of the epidermal growth factor receptor at novel sites mediates receptor interaction with Src and P85 alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210684

21 January 2018

SRC-family kinases are activated in non-small cell lung cancer and promote the survival of epidermal growth factor receptor-dependent cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210684

21 January 2018

An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210684

21 January 2018

Complex mutation patterns of epidermal growth factor receptor gene associated with variable responses to gefitinib treatment in patients with non-small cell lung cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210684

7 January 2021

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