(Q53544046)

15 May 2018

title

Downregulation of c-FLIP promotes caspase-dependent JNK activation and reactive oxygen species accumulation in tumor cells. (English)

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15 May 2018

main subject

reactive oxygen species

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Nakajima A

1

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15 May 2018

Kojima Y

2

1 reference

15 May 2018

Nakayama M

3

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15 May 2018

Yagita H

4

1 reference

15 May 2018

Okumura K

5

1 reference

15 May 2018

Nakano H

6

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15 May 2018

language of work or name

English

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publication date

25 June 2007

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15 May 2018

published in

Oncogene

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15 May 2018

volume

27

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15 May 2018

page(s)

76-84

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15 May 2018

issue

1

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15 May 2018

https://scigraph.springernature.com/pub.10.1038/sj.onc.1210624

exact match

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cites work

Control of apoptosis by Rel/NF-kappaB transcription factors

1 reference

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cFLIP regulation of lymphocyte activation and development

21 January 2018

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The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover

21 January 2018

1 reference

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The inhibitor of death receptor signaling, FLICE-inhibitory protein defines a new class of tumor progression factors

21 January 2018

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Death by design: apoptosis, necrosis and autophagy

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210624

Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210624

NF-kappaB at the crossroads of life and death

21 January 2018

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Proteolytic activation of MST/Krs, STE20-related protein kinase, by caspase during apoptosis.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210624

Development by self-digestion: molecular mechanisms and biological functions of autophagy

21 January 2018

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Autophagy in cell death: an innocent convict?

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210624

IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210624

Immune escape of tumors in vivo by expression of cellular FLICE-inhibitory protein

21 January 2018

1 reference

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Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210624

An antiapoptotic protein, c-FLIPL, directly binds to MKK7 and inhibits the JNK pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210624

Reactive oxygen species mediate crosstalk between NF-kappaB and JNK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210624

Multiple pathways of TWEAK-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210624

Molecular dissection of autophagy: two ubiquitin-like systems

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210624

Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210624

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210624

NF-kappaB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death

21 January 2018

1 reference

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ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210624

Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210624

JNK potentiates TNF-stimulated necrosis by increasing the production of cytotoxic reactive oxygen species

21 January 2018

1 reference

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MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis

21 January 2018

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Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development

21 January 2018

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Ferritin Heavy Chain Upregulation by NF-κB Inhibits TNFα-Induced Apoptosis by Suppressing Reactive Oxygen Species

21 January 2018

1 reference

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Electron Transfer between Cytochrome c and p66Shc Generates Reactive Oxygen Species that Trigger Mitochondrial Apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210624

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210624

A JNK-Dependent Pathway Is Required for TNFα-Induced Apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210624

inferred from DOI database lookup

7 January 2021

based on heuristic

Inflammation and necrosis promote tumour growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210624

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1210624

1 reference

15 May 2018

Dimensions Publication ID

0 references

1 reference

15 May 2018