(Q53547512)

15 May 2018

title

A conserved physical and functional interaction between the cell cycle checkpoint clamp loader and DNA ligase I of eukaryotes. (English)

1 reference

15 May 2018

author name string

Wei Song

1

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15 May 2018

David S Levin

2

1 reference

15 May 2018

Johnson Varkey

3

1 reference

15 May 2018

Sean Post

4

1 reference

15 May 2018

Vladimir P Bermudez

5

1 reference

15 May 2018

Jerard Hurwitz

6

1 reference

15 May 2018

Alan E Tomkinson

7

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15 May 2018

language of work or name

English

0 references

publication date

8 June 2007

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15 May 2018

Journal of Biological Chemistry

number of pages

10

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based on heuristic

inferred from page(s)

published in

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15 May 2018

volume

282

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15 May 2018

issue

31

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15 May 2018

page(s)

22721-22730

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15 May 2018

DNA ligases: structure, reaction mechanism, and function

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Growth retardation and immunodeficiency in a patient with mutations in the DNA ligase I gene

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Cells from an immunodeficient patient (46BR) with a defect in DNA ligation are hypomutable but hypersensitive to the induction of sister chromatid exchanges

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Altered formation of DNA replication intermediates in human 46 BR fibroblast cells hypersensitive to 3-aminobenzamide

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A biochemical defect in the repair of alkylated DNA in cells from an immunodeficient patient (46BR).

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An interaction between DNA ligase I and proliferating cell nuclear antigen: implications for Okazaki fragment synthesis and joining

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Interaction between PCNA and DNA ligase I is critical for joining of Okazaki fragments and long-patch base-excision repair

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DNA ligase I is recruited to sites of DNA replication by an interaction with proliferating cell nuclear antigen: identification of a common targeting mechanism for the assembly of replication factories

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PCNA binding through a conserved motif

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The DNA replication fork in eukaryotic cells.

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Reconstitution of human replication factor C from its five subunits in baculovirus-infected insect cells

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Smart machines at the DNA replication fork.

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A conserved interaction between the replicative clamp loader and DNA ligase in eukaryotes: implications for Okazaki fragment joining

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The C-terminal domain of yeast PCNA is required for physical and functional interactions with Cdc9 DNA ligase

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The PCNA-RFC families of DNA clamps and clamp loaders

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Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro

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Biochemical characterization of DNA damage checkpoint complexes: clamp loader and clamp complexes with specificity for 5' recessed DNA

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Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin

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The checkpoint clamp activates Mec1 kinase during initiation of the DNA damage checkpoint

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The two DNA clamps Rad9/Rad1/Hus1 complex and proliferating cell nuclear antigen differentially regulate flap endonuclease 1 activity.

21 January 2018

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The human checkpoint sensor and alternative DNA clamp Rad9-Rad1-Hus1 modulates the activity of DNA ligase I, a component of the long-patch base excision repair machinery

21 January 2018

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The human Rad9/Rad1/Hus1 damage sensor clamp interacts with DNA polymerase beta and increases its DNA substrate utilisation efficiency: implications for DNA repair

21 January 2018

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The human Rad9-Rad1-Hus1 checkpoint complex stimulates flap endonuclease 1.

21 January 2018

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Mechanism of stimulation of human DNA ligase I by the Rad9-rad1-Hus1 checkpoint complex.

21 January 2018

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Human DNA ligases I, III, and IV-purification and new specific assays for these enzymes

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Human DNA ligase I completely encircles and partially unwinds nicked DNA

21 January 2018

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21 January 2018

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Yeast Rad17/Mec3/Ddc1: a sliding clamp for the DNA damage checkpoint

21 January 2018

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Identification of regions within the four small subunits of human replication factor C required for complex formation and DNA replication

21 January 2018

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

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Cell cycle-dependent phosphorylation of human DNA ligase I at the cyclin-dependent kinase sites.

21 January 2018

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The human checkpoint Rad protein Rad17 is chromatin-associated throughout the cell cycle, localizes to DNA replication sites, and interacts with DNA polymerase

21 January 2018

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A flexible interface between DNA ligase and PCNA supports conformational switching and efficient ligation of DNA.

21 January 2018

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Characterization of human DNA ligase I expressed in a baculovirus-insect cell system.

21 January 2018

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Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA.

21 January 2018

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Etoposide induces the dispersal of DNA ligase I from replication factories

21 January 2018

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DNA ligase I is dephosphorylated during the execution step of etoposide-induced apoptosis

21 January 2018

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Regulation of DNA replication and repair proteins through interaction with the front side of proliferating cell nuclear antigen

21 January 2018

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DNA ligase I and proliferating cell nuclear antigen form a functional complex

21 January 2018

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The replication factory targeting sequence/PCNA-binding site is required in G(1) to control the phosphorylation status of DNA ligase I

21 January 2018

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Cell cycle-dependent dynamic association of cyclin/Cdk complexes with human DNA replication proteins

21 January 2018

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The dispersal of replication proteins after Etoposide treatment requires the cooperation of Nbs1 with the ataxia telangiectasia Rad3-related/Chk1 pathway

21 January 2018

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Retention of the human Rad9 checkpoint complex in extraction-resistant nuclear complexes after DNA damage

21 January 2018

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Genotoxin-induced Rad9-Hus1-Rad1 (9-1-1) chromatin association is an early checkpoint signaling event

21 January 2018

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Replication protein A directs loading of the DNA damage checkpoint clamp to 5'-DNA junctions

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M703774200

1 reference

15 May 2018

1 reference

15 May 2018