(Q53559269)

15 May 2018

title

An early age-related increase in the frequency of CD4+ Foxp3+ cells in BDC2.5NOD mice. (English)

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15 May 2018

author name string

David C Thomas

1

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15 May 2018

Richard J Mellanby

2

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15 May 2018

Jenny M Phillips

3

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15 May 2018

Anne Cooke

4

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15 May 2018

publication date

16 April 2007

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15 May 2018

published in

Immunology

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15 May 2018

volume

121

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15 May 2018

issue

4

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15 May 2018

page(s)

565-576

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15 May 2018

T-lymphocyte clone specific for pancreatic islet antigen

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The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

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X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

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Control of regulatory T cell development by the transcription factor Foxp3

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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

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Autoimmune diabetes onset results from qualitative rather than quantitative age-dependent changes in pathogenic T-cells.

21 January 2018

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TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes

21 January 2018

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Single cell analysis shows decreasing FoxP3 and TGFbeta1 coexpressing CD4+CD25+ regulatory T cells during autoimmune diabetes

21 January 2018

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Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

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Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation

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Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as CD25- regulatory T cells

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CD154 is a negative regulator of autoaggressive CD8+ T cells in type 1 diabetes

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21 January 2018

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B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

21 January 2018

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Pertussis toxin as an adjuvant suppresses the number and function of CD4+CD25+ T regulatory cells

21 January 2018

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Are regulatory T-cells linked with aging?

21 January 2018

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CD4+CD25+ T regulatory cells inhibit cytotoxic activity of CTL and NK cells in humans-impact of immunosenescence.

21 January 2018

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The number of human peripheral blood CD4+ CD25high regulatory T cells increases with age.

21 January 2018

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Decreased proliferative capability of CD4(+) cells of elderly people is associated with faster loss of activation-related antigens and accumulation of regulatory T cells

21 January 2018

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21 January 2018

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Where CD4+CD25+ T reg cells impinge on autoimmune diabetes

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CD4(+) CD25(+) regulatory T cell selection

21 January 2018

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21 January 2018

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21 January 2018

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Unique role of CD4+CD62L+ regulatory T cells in the control of autoimmune diabetes in T cell receptor transgenic mice

21 January 2018

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Diversity of regulatory CD4+T cells controlling distinct organ-specific autoimmune diseases

21 January 2018

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Suppression of disease in New Zealand Black/New Zealand White lupus-prone mice by adoptive transfer of ex vivo expanded regulatory T cells

21 January 2018

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CD4+CD25+Foxp3+ T cells and CD4+CD25-Foxp3+ T cells in aged mice

2 November 2018

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Cutting edge: activation of the aryl hydrocarbon receptor by 2,3,7,8-tetrachlorodibenzo-p-dioxin generates a population of CD4+ CD25+ cells with characteristics of regulatory T cells

2 November 2018

1 reference

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A peptide of glutamic acid decarboxylase 65 can recruit and expand a diabetogenic T cell clone, BDC2.5, in the pancreas.

2 November 2018

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Middle-age male mice have increased severity of experimental autoimmune encephalomyelitis and are unresponsive to testosterone therapy

2 November 2018

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CD4+CD25- T cells in aged mice are hyporesponsive and exhibit suppressive activity

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265971

Regulation of diabetes development by regulatory T cells in pancreatic islet antigen-specific TCR transgenic nonobese diabetic mice.

2 November 2018

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CD25+CD4+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses

2 November 2018

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Cutting edge: interactions through the IL-10 receptor regulate autoimmune diabetes

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265971

Following a diabetogenic T cell from genesis through pathogenesis

2 November 2018

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12 December 2020

Genetic control of diabetes progression

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12 December 2020

Only the CD62L+ subpopulation of CD4+CD25+ regulatory T cells protects from lethal acute GVHD

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12 December 2020

Characterization of peripheral regulatory CD4+ T cells that prevent diabetes onset in nonobese diabetic mice

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12 December 2020

Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide

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12 December 2020

T cell regulation: a special job or everyone's responsibility?

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12 December 2020

Damage control, rather than unresponsiveness, effected by protective DX5+ T cells in autoimmune diabetes

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12 December 2020

A unique subpopulation of CD4+ regulatory T cells controls wasting disease, IL-10 secretion and T cell homeostasis

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12 December 2020

Aging-dependent generation of suppressive CD4+CD25-R123loCD103+ T cells in mice

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12 December 2020

Dynamics of pathogenic and suppressor T cells in autoimmune diabetes development

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12 December 2020

Cutting edge: self-peptides drive the peripheral expansion of CD4+CD25+ regulatory T cells

1 reference

12 December 2020

Regulatory T cells mediate maternal tolerance to the fetus

1 reference

12 December 2020

10.1111/J.1365-2567.2007.02604.X

Identifiers

DOI

1 reference

15 May 2018

PMC publication ID

2265971

0 references

1 reference

15 May 2018