(Q53575717)

15 May 2018

title

Intrachromosomal amplification of chromosome 21 (iAMP21) may arise from a breakage-fusion-bridge cycle. (English)

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15 May 2018

author

Christine J Harrison

2

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15 May 2018

Anthony V. Moorman

3

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15 May 2018

author name string

Hazel M Robinson

1

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15 May 2018

Ilse Chudoba

4

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15 May 2018

Jonathan C Strefford

5

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15 May 2018

publication date

1 April 2007

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15 May 2018

Genes, Chromosomes and Cancer

published in

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15 May 2018

volume

46

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15 May 2018

issue

4

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15 May 2018

page(s)

318-326

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15 May 2018

Mitotic instability in cancer: is there method in the madness?

cites work

1 reference

Amplification or duplication of chromosome band 21q22 with multiple copies of the AML1 gene and mutation of the TP53 gene in therapy-related MDS and AML

21 January 2018

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7 January 2021

Chromosome 21 abnormalities with AML1 amplification in acute lymphoblastic leukemia

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7 January 2021

The Runx genes: lineage-specific oncogenes and tumor suppressors

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7 January 2021

mBAND: a high resolution multicolor banding technique for the detection of complex intrachromosomal aberrations

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7 January 2021

Initiation of the breakage-fusion-bridge mechanism through common fragile site activation in human breast cancer cells: the model of PIP gene duplication from a break at FRA7I

1 reference

7 January 2021

Amplification of AML1 in childhood acute lymphoblastic leukemias

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7 January 2021

Telomere dysfunction triggers extensive DNA fragmentation and evolution of complex chromosome abnormalities in human malignant tumors

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7 January 2021

Amplification of AML1 on a duplicated chromosome 21 in acute lymphoblastic leukemia: a study of 20 cases.

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7 January 2021

The Leukaemia Research Fund/United Kingdom Cancer Cytogenetics Group Karyotype Database in acute lymphoblastic leukaemia: a valuable resource for patient management. Annotation

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7 January 2021

Interphase molecular cytogenetic screening for chromosomal abnormalities of prognostic significance in childhood acute lymphoblastic leukaemia: a UK Cancer Cytogenetics Group Study.

1 reference

7 January 2021

The DNA sequence of human chromosome 21

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7 January 2021

Spectral karyotyping and fluorescence in situ hybridization detect novel chromosomal aberrations, a recurring involvement of chromosome 21 and amplification of the MYC oncogene in acute myeloid leukaemia M2

1 reference

7 January 2021

The role of Alu repeat clusters as mediators of recurrent chromosomal aberrations in tumors

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7 January 2021

Partial chromosome 21 amplification in a child with acute lymphoblastic leukemia.

1 reference

7 January 2021

Chromosome instability as a result of double-strand breaks near telomeres in mouse embryonic stem cells

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7 January 2021

AML1 gene over-expression in childhood acute lymphoblastic leukemia

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7 January 2021

Normal and transforming functions of RUNX1: a perspective

1 reference

7 January 2021

t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1

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7 January 2021

Outcome heterogeneity in childhood high-hyperdiploid acute lymphoblastic leukemia

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7 January 2021

AML1 amplification in a case of childhood acute lymphoblastic leukemia

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7 January 2021

Chromosome rearrangements resulting from telomere dysfunction and their role in cancer.

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7 January 2021

Amplification of AML1 gene is present in childhood acute lymphoblastic leukemia but not in adult, and is not associated with AML1 gene mutation

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7 January 2021

Amplification of AML1 in acute lymphoblastic leukemia is associated with a poor outcome

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7 January 2021

New mechanisms of AML1 gene alteration in hematological malignancies

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7 January 2021

The loss of a single telomere can result in instability of multiple chromosomes in a human tumor cell line

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7 January 2021

Amplification of band q22 of chromosome 21, including AML1, in older children with acute lymphoblastic leukemia: an emerging molecular cytogenetic subgroup

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7 January 2021

Complex genomic alterations and gene expression in acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21.

1 reference

7 January 2021

Primary, single, autosomal trisomies associated with haematological disorders. United Kingdom Cancer Cytogenetics Group (UKCCG)

1 reference

7 January 2021

Prospective gene expression analysis accurately subtypes acute leukaemia in children and establishes a commonality between hyperdiploidy and t(12;21) in acute lymphoblastic leukaemia

1 reference

7 January 2021

Identifiers

DOI

10.1002/GCC.20412

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15 May 2018

PubMed ID

17243167

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15 May 2018