(Q53579649)

English

Heat shock protein 27 functions in inflammatory gene expression and transforming growth factor-beta-activated kinase-1 (TAK1)-mediated signaling.

scientific article published on 3 January 2007

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17202147

Heat shock protein 27 functions in inflammatory gene expression and transforming growth factor-beta-activated kinase-1 (TAK1)-mediated signaling. (English)

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17202147

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author name string

Kate A Alford

1

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17202147

Sarah Glennie

2

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17202147

Bryony R Turrell

3

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17202147

Lesley Rawlinson

4

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17202147

Jeremy Saklatvala

5

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17202147

Jonathan L E Dean

6

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Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17202147

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publication date

3 January 2007

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Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17202147

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17202147

282

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Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17202147

9

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17202147

6232-6241

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17202147

The heat-shock response

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

The human genome encodes 10 alpha-crystallin-related small heat shock proteins: HspB1-10

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

Phosphorylation of the small heat-shock protein is regulated by interleukin 1, tumour necrosis factor, growth factors, bradykinin and ATP.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

Interleukin 1 and tumour necrosis factor increase phosphorylation of the small heat shock protein. Effects in fibroblasts, Hep G2 and U937 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

Identification of MAPKAP kinase 2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

Crystal structure of a small heat-shock protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

HSP27 multimerization mediated by phosphorylation-sensitive intermolecular interactions at the amino terminus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

Regulation of Hsp27 oligomerization, chaperone function, and protective activity against oxidative stress/tumor necrosis factor alpha by phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

Heat shock resistance conferred by expression of the human HSP27 gene in rodent cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

Tumor necrosis factor-alpha induces changes in the phosphorylation, cellular localization, and oligomerization of human hsp27, a stress protein that confers cellular resistance to this cytokine.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

Small stress proteins as novel regulators of apoptosis. Heat shock protein 27 blocks Fas/APO-1- and staurosporine-induced cell death.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

On the role of Hsp27 in regulating apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

The involvement of AU-rich element-binding proteins in p38 mitogen-activated protein kinase pathway-mediated mRNA stabilisation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase p38 signaling cascade

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

MK2 targets AU-rich elements and regulates biosynthesis of tumor necrosis factor and interleukin-6 independently at different post-transcriptional levels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

Analysis of gene function in somatic mammalian cells using small interfering RNAs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

Dexamethasone destabilizes cyclooxygenase 2 mRNA by inhibiting mitogen-activated protein kinase p38.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

Analysis of mitogen-activated protein kinase pathways used by interleukin 1 in tissues in vivo: activation of hepatic c-Jun N-terminal kinases 1 and 2, and mitogen-activated protein kinase kinases 4 and 7.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

Feedback control of the protein kinase TAK1 by SAPK2a/p38

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

Heat Shock Protein 27 Controls Apoptosis by Regulating Akt Activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

Regulation and function of IKK and IKK-related kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

Essential function for the kinase TAK1 in innate and adaptive immune responses.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

TAK1 is indispensable for development of T cells and prevention of colitis by the generation of regulatory T cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

Essential role of TAK1 in thymocyte development and activation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

Critical roles of threonine 187 phosphorylation in cellular stress-induced rapid and transient activation of transforming growth factor-beta-activated kinase 1 (TAK1) in a signaling complex containing TAK1-binding protein TAB1 and TAB2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

Ubiquitin, TAK1 and IKK: is there a connection?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

MAPKAPK-2-mediated LIM-kinase activation is critical for VEGF-induced actin remodeling and cell migration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610987200

21 January 2018

Identifiers

10.1074/JBC.M610987200

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17202147

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1 reference

https://api.fatcat.wiki/v0/release/mxwxbyx5qzbfzc7c4sc7qsppjq

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17202147

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