(Q53602581)

English

JSI-124 (cucurbitacin I) inhibits Janus kinase-3/signal transducer and activator of transcription-3 signalling, downregulates nucleophosmin-anaplastic lymphoma kinase (ALK), and induces apoptosis in ALK-positive anaplastic large cell lymphoma cells.

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scholarly article

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16939498

JSI-124 (cucurbitacin I) inhibits Janus kinase-3/signal transducer and activator of transcription-3 signalling, downregulates nucleophosmin-anaplastic lymphoma kinase (ALK), and induces apoptosis in ALK-positive anaplastic large cell lymphoma cells. (English)

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16939498

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ALK-positive anaplastic large cell lymphoma

1 reference

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author name string

Xinzhe Shi

1

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16939498

Bevin Franko

2

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16939498

Christine Frantz

3

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16939498

Hesham M Amin

4

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16939498

Raymond Lai

5

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16939498

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publication date

25 August 2006

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16939498

British Journal of Haematology

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Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16939498

135

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Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16939498

1

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16939498

26-32

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16939498

Inhibition of JAK3 induces apoptosis and decreases anaplastic lymphoma kinase activity in anaplastic large cell lymphoma

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2006.06259.X

21 January 2018

Selective inhibition of STAT3 induces apoptosis and G(1) cell cycle arrest in ALK-positive anaplastic large cell lymphoma

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2006.06259.X

21 January 2018

Nucleophosmin-anaplastic lymphoma kinase of large-cell anaplastic lymphoma is a constitutively active tyrosine kinase that utilizes phospholipase C-gamma to mediate its mitogenicity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2006.06259.X

21 January 2018

STATs in oncogenesis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2006.06259.X

21 January 2018

Stat3 as an oncogene

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2006.06259.X

21 January 2018

NPM-ALK transgenic mice spontaneously develop T-cell lymphomas and plasma cell tumors.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2006.06259.X

21 January 2018

Stat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2006.06259.X

21 January 2018

Nucleophosmin-anaplastic lymphoma kinase of anaplastic large-cell lymphoma recruits, activates, and uses pp60c-src to mediate its mitogenicity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2006.06259.X

21 January 2018

Translocations involving anaplastic lymphoma kinase (ALK).

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2006.06259.X

21 January 2018

STAT proteins: novel molecular targets for cancer drug discovery

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2006.06259.X

21 January 2018

What have we learnt from mouse models of NPM-ALK-induced lymphomagenesis?

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2006.06259.X

21 January 2018

Involvement of proteasomes in regulating Jak-STAT pathways upon interleukin-2 stimulation.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2006.06259.X

21 January 2018

Anaplastic lymphoma kinase (ALK) activates Stat3 and protects hematopoietic cells from cell death

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2006.06259.X

21 January 2018

Multilevel dysregulation of STAT3 activation in anaplastic lymphoma kinase-positive T/null-cell lymphoma

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2006.06259.X

21 January 2018

Identifiers

10.1111/J.1365-2141.2006.06259.X

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16939498

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16939498

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