(Q53603656)

16 May 2018

editorial

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title

Perspectives on lantibiotic discovery - where have we failed and what improvements are required? (English)

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16 May 2018

author name string

Stephanie Kate Sandiford

series ordinal

1

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16 May 2018

language of work or name

English

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publication date

19 February 2015

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16 May 2018

Expert Opinion on Drug Discovery

published in

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16 May 2018

volume

10

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16 May 2018

issue

4

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16 May 2018

page(s)

315-320

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16 May 2018

Follow the leader: the use of leader peptides to guide natural product biosynthesis.

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https://api.crossref.org/works/10.1517%2F17460441.2015.1016496

Prepeptide sequence of epidermin, a ribosomally synthesized antibiotic with four sulphide-rings.

21 January 2018

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Epidermin and gallidermin: Staphylococcal lantibiotics

21 January 2018

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Drugs for bad bugs: confronting the challenges of antibacterial discovery

21 January 2018

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Lantibiotics: promising candidates for future applications in health care

21 January 2018

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Multiple activities in lantibiotics--models for the design of novel antibiotics?

21 January 2018

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Role of lipid-bound peptidoglycan precursors in the formation of pores by nisin, epidermin and other lantibiotics

21 January 2018

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An alternative bactericidal mechanism of action for lantibiotic peptides that target lipid II.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17460441.2015.1016496

Bacteriocins as alternative agents for control of multiresistant staphylococcal strains

21 January 2018

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Bacteriocins Pep5 and epidermin inhibit Staphylococcus epidermidis adhesion to catheters.

21 January 2018

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Mersacidin eradicates methicillin-resistant Staphylococcus aureus (MRSA) in a mouse rhinitis model.

21 January 2018

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Biosynthesis, immunity, regulation, mode of action and engineering of the model lantibiotic nisin

21 January 2018

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Pharmacokinetic and pharmacodynamic evaluation of the lantibiotic MU1140.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17460441.2015.1016496

Pharmacodynamic activity of the lantibiotic MU1140.

21 January 2018

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Efficacy of the new lantibiotic NAI-107 in experimental infections induced by multidrug-resistant Gram-positive pathogens

21 January 2018

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Evaluation of NVB302 versus vancomycin activity in an in vitro human gut model of Clostridium difficile infection

21 January 2018

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Emerging treatments in cystic fibrosis

21 January 2018

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"Fingerprinting" -haemolytic streptococci by their production of and sensitivity to bacteriocine-like inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2015.1016496

Triggers and cues that activate antibiotic production by actinomycetes

21 January 2018

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Autoregulation of Nisin Biosynthesis in Lactococcus lactis by Signal Transduction

21 January 2018

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The lantibiotic mersacidin is an autoinducing peptide

21 January 2018

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Novel bacteriocins from lactic acid bacteria (LAB): various structures and applications.

21 January 2018

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Identification of a novel two-peptide lantibiotic, lichenicidin, following rational genome mining for LanM proteins.

21 January 2018

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BAGEL3: Automated identification of genes encoding bacteriocins and (non-)bactericidal posttranslationally modified peptides.

21 January 2018

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antiSMASH 2.0--a versatile platform for genome mining of secondary metabolite producers

21 January 2018

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BACTIBASE second release: a database and tool platform for bacteriocin characterization

21 January 2018

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Small molecules with antimicrobial activity against E. coli and P. aeruginosa identified by high-throughput screening

21 January 2018

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https://api.crossref.org/works/10.1517%2F17460441.2015.1016496

A high-throughput screen identifies a new natural product with broad-spectrum antibacterial activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2015.1016496

Determining the structure and mode of action of microbisporicin, a potent lantibiotic active against multiresistant pathogens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2015.1016496

A novel lantibiotic acting on bacterial cell wall synthesis produced by the uncommon actinomycete Planomonospora sp.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2015.1016496

Bioengineered nisin A derivatives with enhanced activity against both Gram positive and Gram negative pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2015.1016496

Site-directed mutagenesis of the hinge region of nisinZ and properties of nisinZ mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2015.1016496

Dissecting structural and functional diversity of the lantibiotic mersacidin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2015.1016496

Insights into in vivo activities of lantibiotics from gallidermin and epidermin mode-of-action studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2015.1016496

Designing and producing modified, new-to-nature peptides with antimicrobial activity by use of a combination of various lantibiotic modification enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2015.1016496

The vancomycin-nisin(1-12) hybrid restores activity against vancomycin resistant Enterococci

21 January 2018

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https://api.crossref.org/works/10.1517%2F17460441.2015.1016496

A substance inhibiting bacterial growth, produced by certain strains of lactic streptococci

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2015.1016496

Entianin, a novel subtilin-like lantibiotic from Bacillus subtilis subsp. spizizenii DSM 15029T with high antimicrobial activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2015.1016496

Macedocin, a food-grade lantibiotic produced by Streptococcus macedonicus ACA-DC 198

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2015.1016496

10.1517/17460441.2015.1016496

21 January 2018

Identifiers

DOI

1 reference

16 May 2018

PubMed ID

25697059

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16 May 2018