(Q53662131)

17 May 2018

title

Enantioselective Oxidative Aerobic Dealkylation of N-Ethyl Benzylisoquinolines by Employing the Berberine Bridge Enzyme. (English)

1 reference

17 May 2018

1 reference

Joerg H. Schrittwieser

3

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17 May 2018

Peter Macheroux

6

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17 May 2018

Wolfgang Kroutil

7

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17 May 2018

author name string

Somayyeh Gandomkar

1

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17 May 2018

Eva-Maria Fischereder

2

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17 May 2018

Silvia Wallner

4

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17 May 2018

Zohreh Habibi

5

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17 May 2018

language of work or name

English

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publication date

21 October 2015

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17 May 2018

Angewandte Chemie International Edition

published in

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volume

54

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17 May 2018

issue

50

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17 May 2018

page(s)

15051-15054

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17 May 2018

Oxidative N-dealkylation of a carboxylate-bridged diiron(II) precursor complex by reaction with O2 affords the elusive [Fe2(mu-OH)2(mu-O2CR)](3+) core of soluble methane monooxygenase hydroxylase

cites work

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201507970

Probing the Compound I-like reactivity of a bare high-valent oxo iron porphyrin complex: the oxidation of tertiary amines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201507970

Kinetic isotope effects implicate the iron-oxene as the sole oxidant in P450-catalyzed N-dealkylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201507970

Amine oxidative N-dealkylation via cupric hydroperoxide Cu-OOH homolytic cleavage followed by site-specific fenton chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201507970

Iron-catalyzed oxidative amidation of tertiary amines with aldehydes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201507970

Aerobic oxidative N-dealkylation of tertiary amines in aqueous solution catalyzed by rhodium porphyrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201507970

Cytochrome P450-catalyzed dealkylation of atrazine by Rhodococcus sp. strain NI86/21 involves hydrogen atom transfer rather than single electron transfer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201507970

Structure and chemistry of cytochrome P450.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201507970

Metabolism of halazepam by rat liver microsomes: stereoselective formation and N-dealkylation of 3-hydroxyhalazepam

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201507970

Enzymatic N-dealkylation of an N-cyclopropylamine: an unusual fate for the cyclopropyl group

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201507970

Monomeric sarcosine oxidase: structure of a covalently flavinylated amine oxidizing enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201507970

Fenproporex N-dealkylation to amphetamine--enantioselective in vitro studies in human liver microsomes as well as enantioselective in vivo studies in Wistar and Dark Agouti rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201507970

Conversion of reticuline into scoulerine by a cell free preparation from Macleaya microcarpa cell suspension cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201507970

A concerted mechanism for berberine bridge enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201507970

Isotope effects suggest a stepwise mechanism for berberine bridge enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201507970

Biochemical evidence that berberine bridge enzyme belongs to a novel family of flavoproteins containing a bi-covalently attached FAD cofactor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201507970

Structural and mechanistic studies reveal the functional role of bicovalent flavinylation in berberine bridge enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201507970

Biocatalytic organic synthesis of optically pure (S)-scoulerine and berbine and benzylisoquinoline alkaloids

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201507970

Deracemization by simultaneous bio-oxidative kinetic resolution and stereoinversion

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201507970

Characterization and Mechanism of the Berberine Bridge Enzyme, a Covalently Flavinylated Oxidase of Benzophenanthridine Alkaloid Biosynthesis in Plants

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201507970

21 January 2018

Cyclization in concert

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201507970

21 January 2018

From yeast to alkaloids

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201507970

Simple isoquinoline and benzylisoquinoline alkaloids as potential antimicrobial, antimalarial, cytotoxic, and anti-HIV agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201507970

Mechanism of the cardiovascular activity of laudanosine: comparison with papaverine and other benzylisoquinolines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201507970

Asymmetric synthesis of isoquinoline alkaloids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201507970

A Promiscuous De Novo Retro-Aldolase Catalyzes Asymmetric Michael Additions via Schiff Base Intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201507970

Enzyme promiscuity: mechanism and applications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201507970

Catalytic promiscuity in biocatalysis: using old enzymes to form new bonds and follow new pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201507970

Berberine bridge enzyme catalyzes the six electron oxidation of (S)-reticuline to dehydroscoulerine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201507970

Monoamine Oxidase-ω-Transaminase Cascade for the Deracemisation and Dealkylation of Amines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201507970

Biocatalytic Enantioselective Oxidative CC Coupling by Aerobic CH Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201507970

Biocatalytic Oxidative CC Bond Formation Catalysed by the Berberine Bridge Enzyme: Optimal Reaction Conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201507970

21 January 2018

Identifiers

DOI

10.1002/ANIE.201507970

1 reference

17 May 2018

PubMed ID

26487450

1 reference

17 May 2018