(Q53664593)

17 May 2018

title

HIV Nef inhibits T cell migration. (English)

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17 May 2018

author name string

Evangeline Y Choe

1

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17 May 2018

Elena S Schoenberger

2

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17 May 2018

Jerome E Groopman

3

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17 May 2018

In-Woo Park

4

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17 May 2018

language of work or name

English

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publication date

26 September 2002

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17 May 2018

Journal of Biological Chemistry

published in

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17 May 2018

volume

277

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17 May 2018

issue

48

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17 May 2018

page(s)

46079-46084

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17 May 2018

Importance of the nef gene for maintenance of high virus loads and for development of AIDS

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes.

21 January 2018

1 reference

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Identification of a nef allele that causes lymphocyte activation and acute disease in macaque monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

HIV-1 Nef mediates lymphocyte chemotaxis and activation by infected macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

Simian and human immunodeficiency virus Nef proteins use different surfaces to downregulate class I major histocompatibility complex antigen expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

Expression of the type 1 human immunodeficiency virus Nef protein in T cells prevents antigen receptor-mediated induction of interleukin 2 mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

HIV-1 Nef increases T cell activation in a stimulus-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

The solution structure of HIV-1 Nef reveals an unexpected fold and permits delineation of the binding surface for the SH3 domain of Hck tyrosine protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

Nef proteins of distinct HIV-1 or -2 isolates differ in their binding properties for HCK: isolation of a novel Nef binding factor with characteristics of an adaptor protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

Differential T-cell antigen receptor signaling mediated by the Src family kinases Lck and Fyn.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

Human immunodeficiency virus type 1 Nef selectively associates with a catalytically active subpopulation of p21-activated kinase 2 (PAK2) independently of PAK2 binding to Nck or beta-PIX

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

HIV-1 Nef associated PAK and PI3-kinases stimulate Akt-independent Bad-phosphorylation to induce anti-apoptotic signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

Interactions of HIV-1 NEF with cellular signal transducing proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

Live and let die: Nef functions beyond HIV replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

HIV Nef increases T cell ERK MAP kinase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

Leukotriene B(4) stimulates Rac-ERK cascade to generate reactive oxygen species that mediates chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

Dual role of H-Ras in regulation of lymphocyte function antigen-1 activity by stromal cell-derived factor-1alpha: implications for leukocyte transmigration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

Molecular cloning and structure of a pre-B-cell growth-stimulating factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

The alpha-chemokine, stromal cell-derived factor-1alpha, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

Stromal cell-derived factor 1 alpha-induced chemotaxis in T cells is mediated by nitric oxide signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

Chemokines and cell migration in secondary lymphoid organs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

Roles of PI3Ks in leukocyte chemotaxis and phagocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

Neutrophils lacking phosphoinositide 3-kinase gamma show loss of directionality during N-formyl-Met-Leu-Phe-induced chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

A role for p21-activated kinase in endothelial cell migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

Lymphocyte traffic control by chemokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

Cutting edge: T cell migration regulated by CXCR4 chemokine receptor signaling to ZAP-70 tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

Nef triggers a transcriptional program in T cells imitating single-signal T cell activation and inducing HIV virulence mediators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

The Nef protein of HIV-1 associates with rafts and primes T cells for activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

Coupling of PAK-interacting exchange factor PIX to GIT1 promotes focal complex disassembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

The HIV-1 nef protein interferes with phosphatidylinositol 3-kinase activation 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

HIV-Nef enhances interleukin-2 production and phosphatidylinositol 3-kinase activity in a human T cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

RAFTK/Pyk2-mediated cellular signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

Role of the PI3K regulatory subunit in the control of actin organization and cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

The N-Terminus of Nef from HIV-1/SIV Associates with a Protein Complex Containing Lck and a Serine Kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

HIV-1 Nef protein: An invitation to a kill

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

HIV-1 Nef leads to inhibition or activation of T cells depending on its intracellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

PC12 cell neuronal differentiation is associated with prolonged p21ras activity and consequent prolonged ERK activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

Stromal cell-derived factor 1/CXCR4 signaling is critical for early human T-cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204698200

21 January 2018

Identifiers

DOI

10.1074/JBC.M204698200

1 reference

17 May 2018

1 reference

17 May 2018