(Q53685193)

English

Multiple sclerosis is associated with an imbalance between tumour necrosis factor-alpha (TNF-alpha)- and IL-10-secreting blood cells that is corrected by interferon-beta (IFN-beta) treatment.

scientific article published in April 2000

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10759776%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Multiple sclerosis is associated with an imbalance between tumour necrosis factor-alpha (TNF-alpha)- and IL-10-secreting blood cells that is corrected by interferon-beta (IFN-beta) treatment (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10759776%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

multiple sclerosis

0 references

0 references

Mathilde Kouwenhoven

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10759776%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10759776%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

author name string

Y M Huang

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10759776%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

P Kivisäkk

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10759776%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

H Link

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10759776%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

publication date

1 April 2000

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10759776%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Clinical and Experimental Immunology

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10759776%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

120

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10759776%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10759776%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

147-153

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10759776%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Multiple sclerosis: a coordinated immunological attack against myelin in the central nervous system

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2000.01175.X

21 January 2018

Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS)

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2000.01175.X

21 January 2018

Multiple sclerosis: levels of interleukin-10-secreting blood mononuclear cells are low in untreated patients but augmented during interferon-beta-1b treatment

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2000.01175.X

21 January 2018

Cellular responses to moderate and heavy exercise

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2000.01175.X

21 January 2018

Effect of food restriction on life span and immune functions in long-lived Fischer-344 x Brown Norway F1 rats.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2000.01175.X

21 January 2018

Stressor-induced alteration of cytokine production in multiple sclerosis patients and controls

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2000.01175.X

21 January 2018

Interleukin-6 (IL-6)--a molecule with both beneficial and destructive potentials

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2000.01175.X

21 January 2018

IL-6 detection in multiple sclerosis brain.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2000.01175.X

21 January 2018

IL-6-deficient mice are resistant to the induction of experimental autoimmune encephalomyelitis provoked by myelin oligodendrocyte glycoprotein

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2000.01175.X

21 January 2018

IL-6 and APPs: anti-inflammatory and immunosuppressive mediators

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2000.01175.X

21 January 2018

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2000.01175.X

21 January 2018

Suppression of acute and protracted-relapsing experimental allergic encephalomyelitis by nasal administration of low-dose IL-10 in rats

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2000.01175.X

21 January 2018

Cerebrospinal fluid interleukin 6 in amyotrophic lateral sclerosis: immunological parameter and comparison with inflammatory and non-inflammatory central nervous system diseases

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2000.01175.X

21 January 2018

Inhibition of Th1 polarization by soluble TNF receptor is dependent on antigen-presenting cell-derived IL-12.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1905623

7 September 2018

Measurement of serum cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1905623

7 September 2018

High IL-6 and low IL-10 in the central nervous system are associated with protracted relapsing EAE in DA rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1905623

7 September 2018

Review: cytokines and the pathogenesis of multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1905623

7 September 2018

Augmented expression of tumour necrosis factor-alpha and lymphotoxin in mononuclear cells in multiple sclerosis and optic neuritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1905623

7 September 2018

New diagnostic criteria for multiple sclerosis: guidelines for research protocols

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1905623

7 September 2018

Studies in myasthenia gravis: review of a twenty-year experience in over 1200 patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1905623

7 September 2018

Acetylcholine receptor-reactive T and B cells in myasthenia gravis and controls

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1905623

7 September 2018

Reverse ELISPOT assay for clonal analysis of cytokine production I. Enumeration of gamma-interferon-secreting cells

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2000.01175.X

21 January 2018

A comparison between ELISPOT methods for the detection of cytokine producing cells: greater sensitivity and specificity using ELISA plates as compared to nitrocellulose membranes

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2000.01175.X

21 January 2018

Cytokine levels in the cerebrospinal fluid and serum of patients with multiple sclerosis

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2000.01175.X

21 January 2018

Increased interleukin-6 mRNA expression in blood and cerebrospinal fluid mononuclear cells in multiple sclerosis

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2000.01175.X

21 January 2018

Quantitative intracellular cytokine measurement: age-related changes in proinflammatory cytokine production

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2000.01175.X

21 January 2018

Interleukin-2 secreting cells in multiple sclerosis and controls

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2000.01175.X

21 January 2018

Interferon effects on interleukin-10 secretion. Mononuclear cell response to interleukin-10 is normal in multiple sclerosis patients

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2000.01175.X

21 January 2018

Interferon beta in the treatment of multiple sclerosis: mechanisms of action

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2000.01175.X

21 January 2018

In vivo effects of interferon beta-1a on immunosuppressive cytokines in multiple sclerosis

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2000.01175.X

21 January 2018

Tumor necrosis factor in serum and cerebrospinal fluid of patients with multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10759776

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoreactive T and B cells responding to myelin proteolipid protein in multiple sclerosis and controls

1 reference

https://pubmed.ncbi.nlm.nih.gov/10759776

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection and quantitation of cells secreting IL-6 under physiologic conditions in BALB/c mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10759776

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased transforming growth factor-beta, interleukin-4, and interferon-gamma in multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10759776

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct comparison of ELISPOT and ELISA-based assays for detection of individual cytokine-secreting cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10759776

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased mRNA expression of IL-10 in mononuclear cells in multiple sclerosis and optic neuritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10759776

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon beta-1b in the treatment of multiple sclerosis: final outcome of the randomized controlled trial. The IFNB Multiple Sclerosis Study Group and The University of British Columbia MS/MRI Analysis Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/10759776

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant Interferon-β blocks proliferation but enhances interleukin-10 secretion by activated human T-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10759776

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low serum interleukin-10 levels in multiple sclerosis: further evidence for decreased systemic immunosuppression?

1 reference

https://pubmed.ncbi.nlm.nih.gov/10759776

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Placebo-controlled multicentre randomised trial of interferon beta-1b in treatment of secondary progressive multiple sclerosis. European Study Group on interferon beta-1b in secondary progressive MS

1 reference

https://pubmed.ncbi.nlm.nih.gov/10759776

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1046/J.1365-2249.2000.01175.X

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10759776%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

PMC publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10759776%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

ResearchGate publication ID

0 references

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