(Q53933574)

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EGF activates an inducible survival response via the RAS-> Erk-1/2 pathway to counteract interferon-alpha-mediated apoptosis in epidermoid cancer cells.

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scholarly article

1 reference

Europe PubMed Central

22 May 2018

http://europepmc.org/abstract/MED/12700650

EGF activates an inducible survival response via the RAS-> Erk-1/2 pathway to counteract interferon-alpha-mediated apoptosis in epidermoid cancer cells. (English)

1 reference

Europe PubMed Central

22 May 2018

http://europepmc.org/abstract/MED/12700650

Michele Caraglia

1

1 reference

Europe PubMed Central

22 May 2018

http://europepmc.org/abstract/MED/12700650

Alfredo Budillon

5

1 reference

Europe PubMed Central

22 May 2018

http://europepmc.org/abstract/MED/12700650

author name string

P Tagliaferri

2

1 reference

Europe PubMed Central

22 May 2018

http://europepmc.org/abstract/MED/12700650

M Marra

3

1 reference

Europe PubMed Central

22 May 2018

http://europepmc.org/abstract/MED/12700650

G Giuberti

4

1 reference

Europe PubMed Central

22 May 2018

http://europepmc.org/abstract/MED/12700650

E Di Gennaro

6

1 reference

Europe PubMed Central

22 May 2018

http://europepmc.org/abstract/MED/12700650

S Pepe

7

1 reference

Europe PubMed Central

22 May 2018

http://europepmc.org/abstract/MED/12700650

G Vitale

8

1 reference

Europe PubMed Central

22 May 2018

http://europepmc.org/abstract/MED/12700650

S Improta

9

1 reference

Europe PubMed Central

22 May 2018

http://europepmc.org/abstract/MED/12700650

P Tassone

10

1 reference

Europe PubMed Central

22 May 2018

http://europepmc.org/abstract/MED/12700650

S Venuta

11

1 reference

Europe PubMed Central

22 May 2018

http://europepmc.org/abstract/MED/12700650

A R Bianco

12

1 reference

Europe PubMed Central

22 May 2018

http://europepmc.org/abstract/MED/12700650

A Abbruzzese

13

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22 May 2018

http://europepmc.org/abstract/MED/12700650

publication date

1 February 2003

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Europe PubMed Central

22 May 2018

http://europepmc.org/abstract/MED/12700650

Cell Death & Differentiation

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22 May 2018

http://europepmc.org/abstract/MED/12700650

10

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Europe PubMed Central

22 May 2018

http://europepmc.org/abstract/MED/12700650

2

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22 May 2018

http://europepmc.org/abstract/MED/12700650

218-229

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Europe PubMed Central

22 May 2018

http://europepmc.org/abstract/MED/12700650

https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401131

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The EGF receptor provides an essential survival signal for SOS-dependent skin tumor development

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Bad overexpression sensitizes NIH/3T3 cells to undergo apoptosis which involves caspase activation and ERK inactivation

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8-Cl-cAMP antagonizes mitogen-activated protein kinase activation and cell growth stimulation induced by epidermal growth factor.

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Phosphorylation and regulation of Raf by Akt (protein kinase B)

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Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

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Prevention of v-Ha-Ras-dependent apoptosis by PDGF coordinates in phosphorylation of ERK and Akt.

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Apoptosis suppression by Raf-1 and MEK1 requires MEK- and phosphatidylinositol 3-kinase-dependent signals

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Akt regulates cell survival and apoptosis at a postmitochondrial level

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The involvement of PI 3-K/Akt-dependent up-regulation of Mcl-1 in the prevention of apoptosis of Hep3B cells by interleukin-6.

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Fibroblast growth factor and insulin-like growth factor differentially modulate the apoptosis and G1 arrest induced by anti-epidermal growth factor receptor monoclonal antibody.

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Ras/MEK signaling suppresses Myc-dependent apoptosis in cells transformed by c-myc and activated ras.

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Interferon-alpha induces apoptosis in human KB cells through a stress-dependent mitogen activated protein kinase pathway that is antagonized by epidermal growth factor

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alpha-Interferon potentiates epidermal growth factor receptor-mediated effects on human epidermoid carcinoma KB cells

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Identifiers

10.1038/SJ.CDD.4401131

1 reference

Europe PubMed Central

22 May 2018

http://europepmc.org/abstract/MED/12700650

1 reference

Europe PubMed Central

22 May 2018

http://europepmc.org/abstract/MED/12700650

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