(Q53937609)

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Pharmacokinetics of the nitric oxide synthase inhibitor L-NG-methylarginine hydrochloride in patients with septic shock. Glaxo Wellcome International Septic Shock Study Group.

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10 December 2019

Pharmacokinetics of the nitric oxide synthase inhibitor L-NG-methylarginine hydrochloride in patients with septic shock. Glaxo Wellcome International Septic Shock Study Group (English)

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Europe PubMed Central

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10 December 2019

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based on heuristic

inferred from title

pharmacokinetics

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based on heuristic

inferred from title

Jean-Louis Vincent

11

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10 December 2019

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Hussein Z

1

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10 December 2019

Beerahee M

2

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10 December 2019

Grover R

3

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10 December 2019

Jordan B

4

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10 December 2019

Jeffs R

5

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10 December 2019

Donaldson J

6

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10 December 2019

Zaccardelli D

7

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10 December 2019

Colice G

8

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10 December 2019

Guntupalli K

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10 December 2019

Watson D

10

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10 December 2019

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1 January 1999

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10 December 2019

Clinical Pharmacology & Therapeutics

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10 December 2019

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10 December 2019

1

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10 December 2019

1-9

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10 December 2019

Septic shock: pathogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2899%2970116-5

7 January 2021

Pathogenetic mechanisms of septic shock

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2899%2970116-5

7 January 2021

Septic shock in humans. Advances in the understanding of pathogenesis, cardiovascular dysfunction, and therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2899%2970116-5

7 January 2021

The sepsis syndrome in a Dutch university hospital. Clinical observations

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2899%2970116-5

7 January 2021

Temporal hemodynamic and oxygen transport patterns in medical patients. Septic shock

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2899%2970116-5

7 January 2021

The L-arginine-nitric oxide pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2899%2970116-5

7 January 2021

Role of endothelium-derived nitric oxide in the regulation of blood pressure

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2899%2970116-5

7 January 2021

Dexamethasone prevents the induction by endotoxin of a nitric oxide synthase and the associated effects on vascular tone: an insight into endotoxin shock

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2899%2970116-5

7 January 2021

Reversal of endotoxin-mediated shock by NG-methyl-L-arginine, an inhibitor of nitric oxide synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2899%2970116-5

7 January 2021

NG-methyl-L-arginine inhibits tumor necrosis factor-induced hypotension: implications for the involvement of nitric oxide

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2899%2970116-5

7 January 2021

Overproduction of nitric oxide in cytokine-mediated and septic shock

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2899%2970116-5

7 January 2021

Nitrogen oxide levels in patients after trauma and during sepsis

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2899%2970116-5

7 January 2021

Plasma nitric oxide levels in newborn infants with sepsis.

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2899%2970116-5

7 January 2021

Cytokines, nitrite/nitrate, soluble tumor necrosis factor receptors, and procalcitonin concentrations: comparisons in patients with septic shock, cardiogenic shock, and bacterial pneumonia

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2899%2970116-5

7 January 2021

Differential expression of iNOS and cNOS mRNA in human vascular smooth muscle cells and endothelial cells under normal and inflammatory conditions

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2899%2970116-5

7 January 2021

The discovery of nitric oxide in the vessel wall. A unifying concept in the pathogenesis of sepsis

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2899%2970116-5

7 January 2021

The metabolism of L-arginine and its significance for the biosynthesis of endothelium-derived relaxing factor: cultured endothelial cells recycle L-citrulline to L-arginine

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2899%2970116-5

7 January 2021

NG-Methyl-L-arginine functions as an alternate substrate and mechanism-based inhibitor of nitric oxide synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2899%2970116-5

7 January 2021

Determination of methylated amino acids in human serum by high-performance liquid chromatography

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2899%2970116-5

7 January 2021

Urinary excretion of methylarginine in human disease

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2899%2970116-5

7 January 2021

Nitric oxide regulates basal systemic and pulmonary vascular resistance in healthy humans

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2899%2970116-5

7 January 2021

Effects of a nitric oxide synthase inhibitor in humans with septic shock

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2899%2970116-5

7 January 2021

Metabolism of NG-monomethyl-L-arginine

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2899%2970116-5

7 January 2021

Studies on the catabolism of NG-methylarginine, NG, NG-dimethylarginine and NG, NG-dimethylarginine in the rabbit

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2899%2970116-5

7 January 2021

Metabolism of methylarginines by human vasculature; implications for the regulation of nitric oxide synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2899%2970116-5

7 January 2021

Use of the ASTED system to determine L-NG-monomethylarginine (546C88) in human plasma by pre-column o-phthalaldehyde derivatisation and high-performance liquid chromatography.

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2899%2970116-5

7 January 2021

Pharmacokinetics, disposition and metabolism of 546C88 (L-NG-methylarginine hydrochloride) in rat and dog

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9236%2899%2970116-5

7 January 2021

Identifiers

10.1016/S0009-9236(99)70116-5

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9951425%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9951425%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

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