(Q53956545)

22 May 2018

title

Kinetics of lactone hydrolysis in antitumor drugs of camptothecin series as studied by fluorescence spectroscopy. (English)

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22 May 2018

fluorescence spectroscopy

main subject

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author

Igor Chourpa

1

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22 May 2018

Jean-François Riou

4

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22 May 2018

author name string

J M Millot

2

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22 May 2018

G D Sockalingum

3

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22 May 2018

M Manfait

5

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22 May 2018

publication date

1 March 1998

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22 May 2018

Biochimica et Biophysica Acta

published in

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22 May 2018

volume

1379

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22 May 2018

page(s)

353-366

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22 May 2018

issue

3

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22 May 2018

Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata1,2

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Plant antitumor agents. 25. Total synthesis and antileukemic activity of ring A substituted camptothecin analogues. Structure-activity correlations

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Plant antitumor agents. 28. Resolution of a key tricyclic synthon, 5'(RS)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3' ,4'- f]delta 6,8-tetrahydro-indolizine: total synthesis and antitumor activity of 20(S)- and 20(R)-camptothecin

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DNA topoisomerase-targeting antitumor drugs can be studied in yeast

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Modification of the hydroxy lactone ring of camptothecin: inhibition of mammalian topoisomerase I and biological activity

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Plant antitumor agents. 18. Synthesis and biological activity of camptothecin analogues

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Interaction of an alkylating camptothecin derivative with a DNA base at topoisomerase I-DNA cleavage sites

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A kinetic and mechanistic study of the hydrolysis of camptothecin and some analogues

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The current status of camptothecin analogues as antitumor agents

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Plant antitumor agents. 29. Synthesis and biological activity of ring D and ring E modified analogues of camptothecin

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Lipid bilayer partitioning and stability of camptothecin drugs

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The structural basis of camptothecin interactions with human serum albumin: impact on drug stability

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Differential interactions of camptothecin lactone and carboxylate forms with human blood components.

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Structure-activity relation in camptothecin antitumor drugs: why a detailed molecular characterisation of their lactone and carboxylate forms by Raman and SERS spectroscopies?

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Scanning microspectrofluorometry of rhodamine 123 in multidrug-resistant cells.

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Confocal spectral imaging analysis in studies of the spatial distribution of antitumour drugs within living cancer cells

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Comparative studies of antitumor DNA intercalating agents, aclacinomycin and saintopin, by means of surface-enhanced Raman scattering spectroscopy

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Molecular Interactions of DNA-Topoisomerase I and II Inhibitor with DNA and Topoisomerases and in Ternary Complexes: Binding Modes and Biological Effects for Intoplicine Derivatives

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Intracellular molecular interactions of antitumor drug amsacrine (m-AMSA) as revealed by surface-enhanced Raman spectroscopy

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7 January 2021

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Identifiers

DOI

1 reference

22 May 2018

PubMed ID

9545598

1 reference

22 May 2018