(Q53970526)

English

Inhibition of glucose-induced insulin secretion by the diacylglycerol lipase inhibitor RHC 80267 and the phospholipase A2 inhibitor ACA through stimulation of K+ permeability without diminution by exogenous arachidonic acid.

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Europe PubMed Central

PubMed publication ID

23 May 2018

http://europepmc.org/abstract/MED/9175712

Inhibition of glucose-induced insulin secretion by the diacylglycerol lipase inhibitor RHC 80267 and the phospholipase A2 inhibitor ACA through stimulation of K+ permeability without diminution by exogenous arachidonic acid. (English)

1 reference

Europe PubMed Central

PubMed publication ID

23 May 2018

http://europepmc.org/abstract/MED/9175712

triacylglycerol lipase inhibitor

1 reference

based on heuristic

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author name string

P Thams

1

1 reference

Europe PubMed Central

PubMed publication ID

23 May 2018

http://europepmc.org/abstract/MED/9175712

K Capito

2

1 reference

Europe PubMed Central

PubMed publication ID

23 May 2018

http://europepmc.org/abstract/MED/9175712

language of work or name

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publication date

1 April 1997

1 reference

Europe PubMed Central

PubMed publication ID

23 May 2018

http://europepmc.org/abstract/MED/9175712

Biochemical Pharmacology

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Europe PubMed Central

PubMed publication ID

23 May 2018

http://europepmc.org/abstract/MED/9175712

53

1 reference

Europe PubMed Central

PubMed publication ID

23 May 2018

http://europepmc.org/abstract/MED/9175712

8

1 reference

Europe PubMed Central

PubMed publication ID

23 May 2018

http://europepmc.org/abstract/MED/9175712

1077-1086

1 reference

Europe PubMed Central

PubMed publication ID

23 May 2018

http://europepmc.org/abstract/MED/9175712

Ca2+, cAMP, and phospholipid-derived messengers in coupling mechanisms of insulin secretion

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Unmasking of arachidonate-induced insulin release by removal of extracellular calcium. Arachidonic acid mobilizes cellular calcium in rat islets of Langerhans

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Exogenous arachidonic acid promotes insulin release from intact or permeabilized rat islets by dual mechanisms. Putative activation of Ca2+ mobilization and protein kinase C.

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Free fatty acid accumulation in secretagogue-stimulated pancreatic islets and effects of arachidonate on depolarization-induced insulin secretion

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Inhibition of arachidonate release by secretagogue-stimulated pancreatic islets suppresses both insulin secretion and the rise in beta-cell cytosolic calcium ion concentration

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Phospholipase A2 activity in pancreatic islets is calcium-dependent and stimulated by glucose

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Diacylglycerol hydrolysis to arachidonic acid is necessary for insulin secretion from isolated pancreatic islets: sequential actions of diacylglycerol and monoacylglycerol lipases

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Stimulation of insulin release by the phorbol ester 12-O-tetradecanoylphorbol 13-acetate in the clonal cell line RINm5F despite a lowering of the free cytoplasmic Ca2+ concentration

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Opposite effects of tolbutamide and diazoxide on the ATP-dependent K+ channel in mouse pancreatic beta-cells

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7 January 2021

Potentiators of insulin secretion modulate Ca2+ sensitivity in rat pancreatic islets

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7 January 2021

Effect of diacylglycerol lipase inhibitor RHC 80267 on pancreatic mouse islet metabolism and insulin secretion

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7 January 2021

Ionization and phase behavior of fatty acids in water: application of the Gibbs phase rule

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Stimulation of protein kinase C and insulin release by 1-oleoyl-2-acetyl-glycerol

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ATP-sensitive K+ channels in insulinoma cells are activated by nonesterified fatty acids

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Exogenous arachidonic acid inactivates protein kinase C in mouse pancreatic islets

1 reference

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Arachidonic acid induces an increase in the cytosolic calcium concentration in single pancreatic islet beta cells

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Identifiers

10.1016/S0006-2952(96)00813-1

1 reference

Europe PubMed Central

PubMed publication ID

23 May 2018

http://europepmc.org/abstract/MED/9175712

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

23 May 2018

http://europepmc.org/abstract/MED/9175712

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