(Q53970744)

23 May 2018

title

Mechanism of quinolone action. A drug-induced structural perturbation of the DNA precedes strand cleavage by topoisomerase IV. (English)

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23 May 2018

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K J Marians

1

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23 May 2018

H Hiasa

series ordinal

2

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23 May 2018

language of work or name

English

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publication date

1 April 1997

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23 May 2018

Journal of Biological Chemistry

published in

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23 May 2018

volume

272

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issue

14

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23 May 2018

page(s)

9401-9409

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23 May 2018

The molecular basis of quinolone action

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.14.9401

DNA topoisomerases: essential enzymes and lethal targets

21 January 2018

1 reference

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Topoisomerase poisons: harnessing the dark side of enzyme mechanism.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.14.9401

Nalidixic acid resistance: A second genetic character involved in DNA gyrase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.14.9401

Mechanism of action of nalidixic acid: Purification of Escherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.14.9401

DNA gyrase: structure and function.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.14.9401

Cloning and primary structure of Staphylococcus aureus DNA topoisomerase IV: a primary target of fluoroquinolones

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.14.9401

Neisseria gonorrhoeae acquires mutations in analogous regions of gyrA and parC in fluoroquinolone-resistant isolates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.14.9401

Topoisomerase IV is a target of quinolones in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.14.9401

Mechanism of inhibition of DNA gyrase by analogues of nalidixic acid: the target of the drugs is DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.14.9401

DNA cleavage is not required for the binding of quinolone drugs to the DNA gyrase-DNA complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.14.9401

DNA strand cleavage is required for replication fork arrest by a frozen topoisomerase-quinolone-DNA ternary complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.14.9401

Identification of the DNA sequence from the E. coli terminus region that halts replication forks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.14.9401

57 Sequencing end-labeled DNA with base-specific chemical cleavages

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.14.9401

Cloning and sequencing of the Escherichia coli gyrA gene coding for the A subunit of DNA gyrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.14.9401

The interaction of Escherichia coli topoisomerase IV with DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.14.9401

Structure and mechanism of DNA topoisomerase II

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.14.9401

DNA supercoiling promotes formation of a bent repression loop in lac DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.14.9401

Lac repressor-operator interaction. I. Equilibrium studies

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.272.14.9401

1 reference

23 May 2018

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23 May 2018