(Q53991706)

English

Lactosylceramide is essential for the osteoclastogenesis mediated by macrophage-colony-stimulating factor and receptor activator of nuclear factor-kappa B ligand.

scientific article published in 2001

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

23 May 2018

http://europepmc.org/abstract/MED/11592959

Lactosylceramide is essential for the osteoclastogenesis mediated by macrophage-colony-stimulating factor and receptor activator of nuclear factor-kappa B ligand. (English)

1 reference

Europe PubMed Central

PubMed publication ID

23 May 2018

http://europepmc.org/abstract/MED/11592959

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8

1 reference

Europe PubMed Central

PubMed publication ID

23 May 2018

http://europepmc.org/abstract/MED/11592959

author name string

Iwamoto T

1

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Europe PubMed Central

PubMed publication ID

23 May 2018

http://europepmc.org/abstract/MED/11592959

Fukumoto S

2

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Europe PubMed Central

PubMed publication ID

23 May 2018

http://europepmc.org/abstract/MED/11592959

Kanaoka K

3

1 reference

Europe PubMed Central

PubMed publication ID

23 May 2018

http://europepmc.org/abstract/MED/11592959

Sakai E

4

1 reference

Europe PubMed Central

PubMed publication ID

23 May 2018

http://europepmc.org/abstract/MED/11592959

Shibata M

5

1 reference

Europe PubMed Central

PubMed publication ID

23 May 2018

http://europepmc.org/abstract/MED/11592959

Fukumoto E

6

1 reference

Europe PubMed Central

PubMed publication ID

23 May 2018

http://europepmc.org/abstract/MED/11592959

Inokuchi Ji J

7

1 reference

Europe PubMed Central

PubMed publication ID

23 May 2018

http://europepmc.org/abstract/MED/11592959

Furukawa K

9

1 reference

Europe PubMed Central

PubMed publication ID

23 May 2018

http://europepmc.org/abstract/MED/11592959

Furukawa K

10

1 reference

Europe PubMed Central

PubMed publication ID

23 May 2018

http://europepmc.org/abstract/MED/11592959

Kato Y

11

1 reference

Europe PubMed Central

PubMed publication ID

23 May 2018

http://europepmc.org/abstract/MED/11592959

Mizuno A

12

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Europe PubMed Central

PubMed publication ID

23 May 2018

http://europepmc.org/abstract/MED/11592959

language of work or name

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publication date

9 October 2001

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Europe PubMed Central

PubMed publication ID

23 May 2018

http://europepmc.org/abstract/MED/11592959

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

23 May 2018

http://europepmc.org/abstract/MED/11592959

276

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Europe PubMed Central

PubMed publication ID

23 May 2018

http://europepmc.org/abstract/MED/11592959

49

1 reference

Europe PubMed Central

PubMed publication ID

23 May 2018

http://europepmc.org/abstract/MED/11592959

46031-46038

1 reference

Europe PubMed Central

PubMed publication ID

23 May 2018

http://europepmc.org/abstract/MED/11592959

Modulation of osteoclast differentiation

1 reference

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Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

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Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation

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Macrophage colony stimulating factor restores in vivo bone resorption in the op/op osteopetrotic mouse

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Effect of surgical menopause and estrogen replacement on cytokine release from human blood mononuclear cells

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Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific

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Two TNF receptors

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Gangliosides protect from TNF alpha-induced apoptosis

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Functional rafts in cell membranes

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Insulin and insulin-like growth factor-I receptors similarly stimulate deoxyribonucleic acid synthesis despite differences in cellular protein tyrosine phosphorylation

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A regulatory role for sphingolipids in neuronal growth. Inhibition of sphingolipid synthesis and degradation have opposite effects on axonal branching.

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Glucosylceramide synthase inhibitor inhibits the action of nerve growth factor in PC12 cells.

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Isolation and characterization of osteoclast precursors that differentiate into osteoclasts on calvarial cells within a short period of time.

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21 January 2018

Vascular endothelial growth factor can substitute for macrophage colony-stimulating factor in the support of osteoclastic bone resorption

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21 January 2018

Expression cloning of mouse cDNA of CMP-NeuAc:Lactosylceramide alpha2,3-sialyltransferase, an enzyme that initiates the synthesis of gangliosides

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21 January 2018

Mice with disrupted GM2/GD2 synthase gene lack complex gangliosides but exhibit only subtle defects in their nervous system

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21 January 2018

Complex gangliosides are essential in spermatogenesis of mice: possible roles in the transport of testosterone

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21 January 2018

Characterization of the intracellular domain of receptor activator of NF-kappaB (RANK). Interaction with tumor necrosis factor receptor-associated factors and activation of NF-kappab and c-Jun N-terminal kinase

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21 January 2018

Ganglioside GM1 binds to the Trk protein and regulates receptor function

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21 January 2018

A peptidomimetic antagonist of the alpha(v)beta3 integrin inhibits bone resorption in vitro and prevents osteoporosis in vivo

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21 January 2018

ArgGlyAsp (RGD) peptides and the anti-vitronectin receptor antibody 23C6 inhibit dentine resorption and cell spreading by osteoclasts*1

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21 January 2018

Localization of the gangliosides GD2 and GD3 in adhesion plaques and on the surface of human melanoma cells

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21 January 2018

Disialogangliosides GD2 and GD3 are involved in the attachment of human melanoma and neuroblastoma cells to extracellular matrix proteins

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Synergism between membrane gangliosides and Arg-Gly-Asp-directed glycoprotein receptors in attachment to matrix proteins by melanoma cells

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Tenascin-C inhibits beta1 integrin-dependent cell adhesion and neurite outgrowth on fibronectin by a disialoganglioside-mediated signaling mechanism

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Tenascin-R interferes with integrin-dependent oligodendrocyte precursor cell adhesion by a ganglioside-mediated signalling mechanism

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21 January 2018

Cell cycle arrest induced by an inhibitor of glucosylceramide synthase. Correlation with cyclin-dependent kinases

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Osteopetrosis in mice lacking NF-kappaB1 and NF-kappaB2.

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GD3 synthase gene expression in PC12 cells results in the continuous activation of TrkA and ERK1/2 and enhanced proliferation.

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GM3-enriched Microdomain Involved in Cell Adhesion and Signal Transduction through Carbohydrate-Carbohydrate Interaction in Mouse Melanoma B16 Cells

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Attenuation of Interleukin 2 Signal in the Spleen Cells of Complex Ganglioside-lacking Mice

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The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene

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Interleukin-1 and tumor necrosis factor stimulate the formation of human osteoclastlike cells in vitro

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Tumor necrosis factor enhances GD3 ganglioside expression in cultured human melanocytes

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Glycosphingolipid-enriched signaling domain in mouse neuroblastoma Neuro2a cells. Mechanism of ganglioside-dependent neuritogenesis

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Effects of an Inhibitor of Glucosylceramide Synthase on Glycosphingolipid Synthesis and Neurite Outgrowth in Murine Neuroblastoma Cell Lines1

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Cell adhesion is a prerequisite for osteoclast survival

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Protein expression and functional difference of membrane-bound and soluble receptor activator of NF-kappaB ligand: modulation of the expression by osteotropic factors and cytokines

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Induction of ganglioside biosynthesis and neurite outgrowth of primary cultured neurons by L-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol

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Gangliosides inhibit growth factor-stimulated neurite outgrowth in SH-SY5Y human neuroblastoma cells

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A ceramide analogue inhibits T cell proliferative response through inhibition of glycosphingolipid synthesis and enhancement of N,N-dimethylsphingosine synthesis

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Sphingomyelinase and ceramide inhibit formation of F-actin ring in and bone resorption by rabbit mature osteoclasts

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Lactosylceramide stimulates Ras-GTP loading, kinases (MEK, Raf), p44 mitogen-activated protein kinase, and c-fos expression in human aortic smooth muscle cells

1 reference

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Lactosylceramide mediates tumor necrosis factor-alpha-induced intercellular adhesion molecule-1 (ICAM-1) expression and the adhesion of neutrophil in human umbilical vein endothelial cells

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Identifiers

10.1074/JBC.M104464200

1 reference

Europe PubMed Central

PubMed publication ID

23 May 2018

http://europepmc.org/abstract/MED/11592959

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

23 May 2018

http://europepmc.org/abstract/MED/11592959

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