(Q53994465)

23 May 2018

title

Deformylase as a novel antibacterial target. (English)

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23 May 2018

author name string

Z Yuan

series ordinal

1

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23 May 2018

J Trias

series ordinal

2

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23 May 2018

R J. White

series ordinal

3

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23 May 2018

publication date

1 September 2001

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23 May 2018

published in

Drug Discovery Today

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23 May 2018

volume

6

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23 May 2018

issue

18

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23 May 2018

page(s)

954-961

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23 May 2018

Global transposon mutagenesis and a minimal Mycoplasma genome

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Peptide deformylase as a target for new generation, broad spectrum antimicrobial agents

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Characterization of the Thermus thermophilus locus encoding peptide deformylase and methionyl-tRNA(fMet) formyltransferase

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Peptide deformylase in Staphylococcus aureus: resistance to inhibition is mediated by mutations in the formyltransferase gene

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Resistance of Streptococcus pneumoniae to deformylase inhibitors is due to mutations in defB.

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Formylation is not essential for initiation of protein synthesis in all eubacteria.

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Structure-function relationships within the peptide deformylase family. Evidence for a conserved architecture of the active site involving three conserved motifs and a metal ion.

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Peptide deformylase of eukaryotic protists: a target for new antiparasitic agents?

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Enzymes degrading bacterial chemotactic F-met peptides in human ileal and colonic mucosa

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Identification of eukaryotic peptide deformylases reveals universality of N-terminal protein processing mechanisms

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7 January 2021

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7 January 2021

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7 January 2021

Actinonin, a naturally occurring antibacterial agent, is a potent deformylase inhibitor

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7 January 2021

Design and Synthesis of Substrate Analogue Inhibitors of Peptide Deformylase†

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7 January 2021

Synthesis and antibacterial activity of peptide deformylase inhibitors

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7 January 2021

Hydroxamic acid derivatives as potent peptide deformylase inhibitors and antibacterial agents

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7 January 2021

Antibiotic Activity and Characterization of BB-3497, a Novel Peptide Deformylase Inhibitor

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7 January 2021

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7 January 2021

A new subclass of the zinc metalloproteases superfamily revealed by the solution structure of peptide deformylase

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7 January 2021

Crystal structure of the Escherichia coli peptide deformylase

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7 January 2021

Structural basis for the design of antibiotics targeting peptide deformylase

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7 January 2021

Solution structure of nickel-peptide deformylase

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7 January 2021

Actinonin: an Antibiotic Substance produced by an Actinomycete

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7 January 2021

Peptide deformylase as an antibacterial drug target: target validation and resistance development

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7 January 2021

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7 January 2021

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7 January 2021

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Identifiers

DOI

1 reference

23 May 2018

1 reference

23 May 2018