(Q54036451)

24 May 2018

title

Clinical, pharmacokinetic and biological studies of topotecan. (English)

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24 May 2018

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P J O'Dwyer

1

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24 May 2018

F P LaCreta

2

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24 May 2018

N B Haas

3

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24 May 2018

T Halbherr

4

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24 May 2018

H Frucht

5

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24 May 2018

E Goosenberg

6

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24 May 2018

K S Yao

7

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24 May 2018

publication date

1 January 1994

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24 May 2018

Cancer Chemotherapy and Pharmacology

published in

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24 May 2018

volume

34 Suppl

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24 May 2018

page(s)

S46-52

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24 May 2018

https://scigraph.springernature.com/pub.10.1007/bf00684863

exact match

0 references

cites work

Topoisomerase-targeting antitumor drugs

1 reference

12 December 2020

Phase I and pharmacologic study of topotecan: a novel topoisomerase I inhibitor

1 reference

12 December 2020

Phase I Study of Weekly Intravenous Infusions of CPT-11, a New Derivative of Camptothecin, in the Treatment of Advanced Non-Small-Cell Lung Cancer

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12 December 2020

cDNA cloning of human DNA topoisomerase I: catalytic activity of a 67.7-kDa carboxyl-terminal fragment

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12 December 2020

Evolution of the functional human beta-actin gene and its multi-pseudogene family: conservation of noncoding regions and chromosomal dispersion of pseudogenes

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12 December 2020

Quantitation of thymidylate synthase, dihydrofolate reductase, and DT-diaphorase gene expression in human tumors using the polymerase chain reaction

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12 December 2020

High-performance liquid chromatographic analysis of the new antitumour drug SK&F 104864-A (NSC 609699) in plasma

1 reference

12 December 2020

Establishment of a camptothecin analogue (CPT-11)-resistant cell line of human non-small cell lung cancer: characterization and mechanism of resistance

1 reference

12 December 2020

Decreased expression of DNA topoisomerase I in camptothecin-resistant tumor cell lines as determined by a monoclonal antibody

1 reference

12 December 2020

Activity of topotecan, a new topoisomerase I inhibitor, against human tumor colony-forming units in vitro

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12 December 2020

Characterization of camptothecin-resistant chinese hamster lung cells

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12 December 2020

Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11

1 reference

12 December 2020

Elevation of topoisomerase I messenger RNA, protein, and catalytic activity in human tumors: demonstration of tumor-type specificity and implications for cancer chemotherapy

1 reference

12 December 2020

A phase II study of CPT-11, a new derivative of camptothecin, for previously untreated non-small-cell lung cancer

1 reference

12 December 2020

Phase I trial of low-dose continuous topotecan infusion in patients with cancer: an active and well-tolerated regimen

1 reference

12 December 2020

Variable baseline gamma-glutamylcysteine synthetase messenger RNA expression in peripheral mononuclear cells of cancer patients, and its induction by buthionine sulfoximine treatment.

1 reference

12 December 2020

Phase I/pharmacokinetic study of topotecan by 24-hour continuous infusion weekly

1 reference

12 December 2020

Quantitative and qualitative aspects of topoisomerase I and II alpha and beta in untreated and platinum/cyclophosphamide treated malignant ovarian tumors

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF00684863

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24 May 2018

PubMed ID

8070027

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24 May 2018