(Q54049618)

24 May 2018

title

Pathogenesis of non-insulin-dependent (type II) diabetes mellitus (NIDDM) - genetic predisposition and metabolic abnormalities. (English)

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24 May 2018

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1

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24 May 2018

author name string

Bae HY

2

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24 May 2018

Lee BR

3

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24 May 2018

Koh KS

4

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24 May 2018

Kim YS

5

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24 May 2018

Lee KW

6

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24 May 2018

Kim H

7

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24 May 2018

Yoon J

8

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24 May 2018

language of work or name

English

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publication date

1 February 1999

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24 May 2018

Advanced Drug Delivery Reviews

published in

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24 May 2018

volume

35

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24 May 2018

issue

2-3

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24 May 2018

page(s)

157-177

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24 May 2018

Insulin-dependent diabetes mellitus as a beta-cell targeted disease of immunoregulation

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7 January 2021

Facilitative glucose transporters

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7 January 2021

Sequence, tissue distribution, and chromosomal localization of mRNA encoding a human glucose transporter-like protein

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7 January 2021

Polymorphisms at the GLUT2 (beta-cell/liver) glucose transporter gene and non-insulin-dependent diabetes mellitus (NIDDM): analysis in affected pedigree members

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7 January 2021

Glucokinase as pancreatic beta cell glucose sensor and diabetes gene

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7 January 2021

Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitus

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7 January 2021

Linkage of type 2 diabetes to the glucokinase gene

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7 January 2021

Familial hyperglycemia due to mutations in glucokinase. Definition of a subtype of diabetes mellitus

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7 January 2021

Linkage analysis of the glucokinase locus in familial type 2 (non-insulin-dependent) diabetic pedigrees

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7 January 2021

Gene for non-insulin-dependent diabetes mellitus (maturity-onset diabetes of the young subtype) is linked to DNA polymorphism on human chromosome 20q

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7 January 2021

A gene for maturity onset diabetes of the young (MODY) maps to chromosome 12q

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7 January 2021

Does the mitochondrial DNA play a role in the pathogenesis of diabetes?

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https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Characterization of the adenine nucleotide translocase of pancreatic islet mitochondria

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7 January 2021

Mitochondrial gene mutations and diabetes mellitus

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https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Diabetes mellitus associated with a pathogenic point mutation in mitochondrial DNA

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https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Mitochondrial gene defects in patients with NIDDM

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7 January 2021

Pancreatic beta-cell secretory defect associated with mitochondrial point mutation of the tRNA(LEU(UUR)) gene: a study in seven families with mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS)

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7 January 2021

Prevalence of mitochondrial gene mutations in families with diabetes mellitus

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7 January 2021

Mitochondrial diabetes mellitus: prevalence and clinical characterization of diabetes due to mitochondrial tRNA(Leu(UUR)) gene mutation in Japanese patients.

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7 January 2021

Maternally transmitted diabetes and deafness associated with a 10.4 kb mitochondrial DNA deletion

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7 January 2021

Maternally transmitted partial direct tandem duplication of mitochondrial DNA associated with diabetes mellitus

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7 January 2021

Deletion of mitochondrial DNA in a case of early-onset diabetes mellitus, optic atrophy, and deafness (Wolfram syndrome, MIM 222300).

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7 January 2021

The human glucagon receptor encoding gene: structure, cDNA sequence and chromosomal localization

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7 January 2021

A missense mutation in the glucagon receptor gene is associated with non-insulin-dependent diabetes mellitus

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7 January 2021

Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus

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7 January 2021

Glucagon-like peptide I stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line

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7 January 2021

Proglucagon products in plasma of noninsulin-dependent diabetics and nondiabetic controls in the fasting state and after oral glucose and intravenous arginine

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7 January 2021

Two mutant alleles of the insulin receptor gene in a family with a genetic form of insulin resistance: a 10 base pair deletion in exon 1 and a mutation substituting serine for asparagine-462.

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7 January 2021

The amino acid sequence of the insulin receptor is normal in an insulin-resistant Pima Indian

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Analysis of the gene sequences of the insulin receptor and the insulin-sensitive glucose transporter (GLUT-4) in patients with common-type non-insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Islet amyloid formed from diabetes-associated peptide may be pathogenic in type-2 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Islet amyloid, islet-amyloid polypeptide, and diabetes mellitus

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https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Islet amyloid polypeptide: identification and chromosomal localization of the human gene

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7 January 2021

Non-linkage of the islet amyloid polypeptide gene with Type 2 (non-insulin-dependent) diabetes mellitus

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7 January 2021

Islet amyloid polypeptide (amylin): no evidence of an abnormal precursor sequence in 25 type 2 (non-insulin-dependent) diabetic patients

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7 January 2021

Human insulin receptor substrate-1 gene (IRS1): chromosomal localization to 2q35-q36.1 and identification of a simple tandem repeat DNA polymorphism

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7 January 2021

Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus.

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https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Insulin receptor substrate (IRS-1) gene polymorphisms in French NIDDM families

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7 January 2021

Analysis of three glucose transporter genes in a Caucasian population: no associations with non-insulin-dependent diabetes and obesity

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7 January 2021

Polymorphisms of GLUT2 and GLUT4 genes. Use in evaluation of genetic susceptibility to NIDDM in blacks

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7 January 2021

Polymorphisms at the GLUT1 (HepG2) and GLUT4 (muscle/adipocyte) glucose transporter genes and non-insulin-dependent diabetes mellitus (NIDDM)

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7 January 2021

Glucose transporter gene and non-insulin-dependent diabetes

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7 January 2021

Glucose and free fatty acid metabolism in non-insulin-dependent diabetes mellitus. Evidence for multiple sites of insulin resistance

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7 January 2021

Multiple defects in muscle glycogen synthase activity contribute to reduced glycogen synthesis in non-insulin dependent diabetes mellitus

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7 January 2021

Decreased insulin activation of glycogen synthase in skeletal muscles in young nonobese Caucasian first-degree relatives of patients with non-insulin-dependent diabetes mellitus

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7 January 2021

Assignment of the gene encoding glycogen synthase (GYS) to human chromosome 19, band q13.3.

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7 January 2021

Association between polymorphism of the glycogen synthase gene and non-insulin-dependent diabetes mellitus.

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7 January 2021

Polymorphism of the glycogen synthase gene and non-insulin-dependent diabetes mellitus

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7 January 2021

Simple tandem repeat DNA polymorphism in the human glycogen synthase gene is associated with NIDDM in Japanese subjects

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7 January 2021

Association of a polymorphism in the beta 3-adrenergic-receptor gene with features of the insulin resistance syndrome in Finns.

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7 January 2021

Time of Onset of Non-Insulin-Dependent Diabetes Mellitus and Genetic Variation in the β3-Adrenergic–Receptor Gene

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7 January 2021

A mutation in the beta 3-adrenergic receptor gene is associated with obesity and hyperinsulinemia in Japanese subjects.

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7 January 2021

Genetic variation in the beta 3-adrenergic receptor and an increased capacity to gain weight in patients with morbid obesity

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7 January 2021

Linkage analysis and molecular scanning of glucokinase gene in NIDDM families

1 reference

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7 January 2021

Linkage of chromosomal markers on 4q with a putative gene determining maximal insulin action in Pima Indians

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7 January 2021

Positional cloning of the mouse obese gene and its human homologue

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7 January 2021

Evidence against either a premature stop codon or the absence of obese gene mRNA in human obesity

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7 January 2021

Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects

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7 January 2021

Overexpression of the obese (ob) gene in adipose tissue of human obese subjects

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7 January 2021

Post-translational proteolysis in polypeptide hormone biosynthesis

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7 January 2021

Serum proinsulin levels at fasting and after oral glucose load in patients with type 2 (non-insulin-dependent) diabetes mellitus

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7 January 2021

Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity

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7 January 2021

Identification and analysis of the gene encoding human PC2, a prohormone convertase expressed in neuroendocrine tissues

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7 January 2021

Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

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7 January 2021

Linkage between obesity and a marker near the tumor necrosis factor-alpha locus in Pima Indians

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7 January 2021

Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1

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7 January 2021

Regulation of hepatic glucose metabolism in humans

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7 January 2021

Insulin, glucagon, and glucose as regulators of hepatic glucose uptake and production in vivo

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7 January 2021

Determination of Krebs cycle metabolic carbon exchange in vivo and its use to estimate the individual contributions of gluconeogenesis and glycogenolysis to overall glucose output in man

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7 January 2021

Influence of hyperglycemia on insulin's in vivo effects in type II diabetes

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https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Receptor and postreceptor defects contribute to the insulin resistance in noninsulin-dependent diabetes mellitus

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7 January 2021

Early metabolic defects in persons at increased risk for non-insulin-dependent diabetes mellitus.

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7 January 2021

Postprandial hyperglycemia in patients with noninsulin-dependent diabetes mellitus. Role of hepatic and extrahepatic tissues

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7 January 2021

The disposal of an oral glucose load in patients with non-insulin-dependent diabetes

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7 January 2021

Molecular biology of mammalian glucose transporters

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7 January 2021

Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus

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7 January 2021

Correlation between muscle glycogen synthase activity and in vivo insulin action in man.

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https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Modulation of hepatic glucose production by non-esterified fatty acids in type 2 (non-insulin-dependent) diabetes mellitus

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7 January 2021

Banting lecture 1988. Role of insulin resistance in human disease

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7 January 2021

Plasma insulin concentrations in nondiabetic and early diabetic subjects. Determinations by a new sensitive immuno-assay technic

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Study of the Relationship Between Glucose and Insulin Responses to an Oral Glucose Load in Man

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Fasting hyperglycemia in non-insulin-dependent diabetes mellitus: contributions of excessive hepatic glucose production and impaired tissue glucose uptake.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Insulin responses in equivocal and definite diabetes, with special reference to subjects who had mild glucose intolerance but later developed definite diabetes

1 reference

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7 January 2021

Seminars in Medicine of the Beth Israel Hospital, Boston. Non-insulin-dependent diabetes mellitus - a genetically programmed failure of the beta cell to compensate for insulin resistance

1 reference

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7 January 2021

Preferential release of proinsulin relative to insulin in non-insulin-dependent diabetes mellitus.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Twenty-four-hour profiles and pulsatile patterns of insulin secretion in normal and obese subjects

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Impaired pulsatile secretion of insulin in relatives of patients with non-insulin-dependent diabetes.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Dynamics of Insulin Secretion by the Perfused Rat Pancreas

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Early Phase of Insulin Release

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https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Insulin deficiency and insulin resistance in the pathogenesis of NIDDM: is a divorce possible?

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Low insulin response: a marker of prediabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Measurement of insulin secretion in type 2 diabetes: problems and pitfalls

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Relationships Between Fasting Plasma Glucose Levels and Insulin Secretion During Intravenous Glucose Tolerance Tests

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https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Glucagon physiology and pathophysiology in the light of new advances

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https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Diminished B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus

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https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Insulin, Glucagon, and Glucose Exhibit Synchronous, Sustained Oscillations in Fasting Monkeys

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https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Cyclic Oscillations of Basal Plasma Glucose and Insulin Concentrations in Human Beings

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7 January 2021

Abnormalities of insulin pulsatility and glucose oscillations during meals in obese noninsulin-dependent diabetic patients: effects of weight reduction

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7 January 2021

Regulation of pancreatic insulin and glucagon secretion

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7 January 2021

Defective glucose counterregulation after subcutaneous insulin in noninsulin-dependent diabetes mellitus. Paradoxical suppression of glucose utilization and lack of compensatory increase in glucose production, roles of insulin resistance, abnormal n

1 reference

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7 January 2021

Differential volumetry of A,B and D cells in the pancreatic islets of diabetic and nondiabetic subjects

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7 January 2021

The influence of amyloid deposits on the islet volume in maturity onset diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Islet amyloid and type 2 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Diet-Induced Improvement of Abnormalities in Insulin and Glucagon Secretion and in Insulin Receptor Binding in Diabetes Mellitus*

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Insulin secretion improves following dietary control of plasma glucose in severely hyperglycemic obese patients.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

1 reference

7 January 2021

Natural history of beta-cell dysfunction in NIDDM.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

The loss of GLUT2 expression by glucose-unresponsive beta cells of db/db mice is reversible and is induced by the diabetic environment

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Insulin deficiency and insulin resistance interaction in diabetes: estimation of their relative contribution by feedback analysis from basal plasma insulin and glucose concentrations

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Assessment of insulin sensitivity in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Role of glucose and insulin resistance in development of type 2 diabetes mellitus: results of a 25-year follow-up study

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Sequential changes in serum insulin concentration during development of non-insulin-dependent diabetes.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Slow glucose removal rate and hyperinsulinemia precede the development of type II diabetes in the offspring of diabetic parents.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Impaired glucose tolerance as a disorder of insulin action. Longitudinal and cross-sectional studies in Pima Indians.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Role of glucose transporters in the cellular insulin resistance of type II non-insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Role of insulin resistance in the pathogenesis of NIDDM.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Relationships between insulin secretion, insulin action, and fasting plasma glucose concentration in nondiabetic and noninsulin-dependent diabetic subjects

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Insulin action in non-insulin-dependent diabetes mellitus: the relationship between hepatic and extrahepatic insulin resistance and obesity

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Increased lipolysis and its consequences on gluconeogenesis in non-insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Insulin binding in diabetes. Relationships with plasma insulin levels and insulin sensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Impaired activation of glycogen synthase in people at increased risk for developing NIDDM

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

In vitro insulin resistance of human adipocytes isolated from subjects with noninsulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Facilitative glucose transporters: regulatory mechanisms and dysregulation in diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Glucose transport in cultured human skeletal muscle cells. Regulation by insulin and glucose in nondiabetic and non-insulin-dependent diabetes mellitus subjects

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Effect of fatty acids on glucose production and utilization in man

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Beta-cell dysfunction induced by chronic hyperglycemia. Current ideas on mechanism of impaired glucose-induced insulin secretion

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic rats

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Relation of body fat distribution to metabolic complications of obesity.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Impact of obesity on metabolism in men and women. Importance of regional adipose tissue distribution

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Mechanisms of insulin resistance in human obesity: evidence for receptor and postreceptor defects

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

The association of physical activity with obesity, fat distribution and glucose intolerance in Pima Indians.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Diminished insulin response in highly trained athletes

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Effect of muscle glycogen depletion on in vivo insulin action in man.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Variations in insulin-stimulated glucose uptake in healthy individuals with normal glucose tolerance.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2898%2900071-4

7 January 2021

10.1016/S0169-409X(98)00071-4

Identifiers

DOI

1 reference

24 May 2018

1 reference

24 May 2018