(Q54061261)

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Triapine (3-aminopyridine-2-carboxaldehyde- thiosemicarbazone): A potent inhibitor of ribonucleotide reductase activity with broad spectrum antitumor activity.

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Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10692563

Triapine (3-aminopyridine-2-carboxaldehyde- thiosemicarbazone): A potent inhibitor of ribonucleotide reductase activity with broad spectrum antitumor activity. (English)

1 reference

Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10692563

author name string

Finch RA

1

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Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10692563

Liu M

2

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Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10692563

Grill SP

3

1 reference

Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10692563

Rose WC

4

1 reference

Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10692563

Loomis R

5

1 reference

Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10692563

Vasquez KM

6

1 reference

Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10692563

Cheng Y

7

1 reference

Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10692563

Sartorelli AC

8

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Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10692563

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publication date

1 April 2000

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Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10692563

Biochemical Pharmacology

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PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10692563

59

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Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10692563

8

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Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10692563

983-991

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Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10692563

Reduction of Ribonucleotides

1 reference

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Drug action on ribonucleotide reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900419-0

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Inhibition of tumor cell ribonucleotide reductase by macrophage-derived nitric oxide

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Pharmacokinetics and pharmacodynamics of hydroxyurea

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Characterization of the biochemical mechanism of action of alpha-(N)-heterocyclic carboxaldehyde thiosemicarbazones

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Comparative cytotoxic and biochemical effects of ligands and metal complexes of .alpha.-N-heterocyclic carboxaldehyde thiosemicarbazones

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Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone; 3-AP): an inhibitor of ribonucleotide reductase with antineoplastic activity

1 reference

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7 January 2021

Synthesis and antitumor activity of amino derivatives of pyridine-2-carboxaldehyde thiosemicarbazone

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Synthesis and evaluation of 1-acyl-1,2-bis(methylsulfonyl)-2-(2- chloroethyl)hydrazines as antineoplastic agents.

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A generalized Wilcoxon test for comparing arbitrarily singly-censored samples

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A semiautomated microculture method for investigating growth inhibitory effects of cytotoxic compounds on exponentially growing carcinoma cells

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A rapid assay for CDP reductase activity in mammalian cell extracts

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Inhibitors of ribonucleotide reductase. Comparative effects of amino- and hydroxy-substituted pyridine-2-carboxaldehyde thiosemicarbazones

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7 January 2021

Overexpression of the multidrug resistance genes mdr1, mdr3, and mrp in L1210 leukemia cells resistant to inhibitors of ribonucleotide reductase

1 reference

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7 January 2021

Structure-function relationships for a new series of pyridine-2-carboxaldehyde thiosemicarbazones on ribonucleotide reductase activity and tumor cell growth in culture and in vivo

1 reference

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Effect of iron-chelating agents on inhibitors of ribonucleotide reductase

1 reference

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7 January 2021

Identifiers

10.1016/S0006-2952(99)00419-0

1 reference

Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10692563

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10692563

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