(Q54069069)

24 May 2018

title

In vivo anti-tumor activity of a novel indolocarbazole compound, J-107088, on murine and human tumors transplanted into mice. (English)

1 reference

24 May 2018

author name string

H Arakawa

1

1 reference

24 May 2018

M Morita

2

1 reference

24 May 2018

T Kodera

3

1 reference

24 May 2018

A Okura

4

1 reference

24 May 2018

M Ohkubo

5

1 reference

24 May 2018

H Morishima

6

1 reference

24 May 2018

S Nishimura

7

1 reference

24 May 2018

publication date

1 October 1999

1 reference

24 May 2018

number of pages

8

1 reference

Japanese Journal of Cancer Research

inferred from page(s)

published in

1 reference

24 May 2018

volume

90

1 reference

24 May 2018

issue

10

1 reference

24 May 2018

page(s)

1163-1170

1 reference

24 May 2018

Mode of action of a new indolocarbazole anticancer agent, J-107088, targeting topoisomerase I.

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5925996

Novel antitumor indolocarbazole compound 6-N-formylamino-12,13-dihydro-1,11- dihydroxy-13-(beta-D-glucopyranosyl)-5H-indolo[2,3-a]pyrrolo[3,4- c]carbazole-5,7(6H)-dione (NB-506): induction of topoisomerase I-mediated DNA cleavage and mechanisms of c

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5925996

Quantitative comparison of toxicity of anticancer agents in mouse, rat, hamster, dog, monkey, and man.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5925996

Activity of a novel 4-quinolinecarboxylic acid, NSC 368390 [6-fluoro-2-(2'-fluoro-1,1'-biphenyl-4-yl)-3-methyl-4-quinolinecarb oxylic acid sodium salt], against experimental tumors.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5925996

A new antitumor substance, BE-13793C, produced by a streptomycete. Taxonomy, fermentation, isolation, structure determination and biological activity

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5925996

Antimetastatic effect of a novel indolocarbazole (NB-506) on IMC-HM murine tumor cells metastasized to the liver.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5925996

ED-110, a novel indolocarbazole, prevents the growth of experimental tumors in mice.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5925996

Synthesis and biological activities of topoisomerase I inhibitors, 6-N-amino analogues of NB-506

13 August 2018

1 reference

12 December 2020

Novel indolocarbazole compound 6-N-formylamino-12,13-dihydro-1,11-dihydroxy- 13-(beta-D-glucopyranosyl)-5H-indolo[2,3-a]pyrrolo-[3,4-c]carbazole- 5,7(6H)-dione (NB-506): its potent antitumor activities in mice

1 reference

12 December 2020

Induction of topoisomerase I-mediated DNA cleavage by a new indolocarbazole, ED-110

1 reference

12 December 2020

Substitution at the F-ring N-imide of the indolocarbazole antitumor drug NB-506 increases the cytotoxicity, DNA binding, and topoisomerase I inhibition activities

1 reference

12 December 2020

10.1111/J.1349-7006.1999.TB00691.X

Identifiers

DOI

1 reference

24 May 2018

PMCID

5925996

1 reference

24 May 2018

PubMed ID

10595746

1 reference

24 May 2018