(Q54117223)

25 May 2018

title

Enhancement of human protein C function by site-directed mutagenesis of the gamma-carboxyglutamic acid domain. (English)

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25 May 2018

author name string

Shen L

1

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25 May 2018

Shah AM

2

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25 May 2018

Dahlbäck B

3

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25 May 2018

Nelsestuen GL

4

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25 May 2018

language of work or name

English

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publication date

1 November 1998

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25 May 2018

Journal of Biological Chemistry

published in

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25 May 2018

volume

273

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issue

47

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25 May 2018

page(s)

31086-31091

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25 May 2018

describes a project that uses

site-directed mutagenesis

1 reference

based on heuristic

inferred from title

cites work

Comparison of naturally occurring vitamin K-dependent proteins: correlation of amino acid sequences and membrane binding properties suggests a membrane contact site

1 reference

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Enhancing the activity of protein C by mutagenesis to improve the membrane-binding site: studies related to proline-10.

21 January 2018

1 reference

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Manipulation of the membrane binding site of vitamin K-dependent proteins: enhanced biological function of human factor VII.

21 January 2018

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A chimeric protein C containing the prothrombin Gla domain exhibits increased anticoagulant activity and altered phospholipid specificity.

21 January 2018

1 reference

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Structure-function assessment of the role of the helical stack domain in the properties of human recombinant protein C and activated protein C.

21 January 2018

1 reference

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Functions of individual gamma-carboxyglutamic acid (Gla) residues of human protein c. Determination of functionally nonessential Gla residues and correlations with their mode of binding to calcium

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31086

Highly conserved residue arginine-15 is required for the Ca2+-dependent properties of the gamma-carboxyglutamic acid domain of human anticoagulation protein C and activated protein C.

21 January 2018

1 reference

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Production of large unilamellar vesicles by a rapid extrusion procedure: characterization of size distribution, trapped volume and ability to maintain a membrane potential

21 January 2018

1 reference

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Equilibria involved in prothrombin- and blood-clotting factor X-membrane binding

21 January 2018

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Bovine factors X1and X 2 (Stuart factor). Isolation and characterization

21 January 2018

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The Mode of Action of Vitamin K. Isolation of a Peptide Containing the Vitamin K-Dependent Portion of Prothrombin

21 January 2018

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The protein C anticoagulant system: inherited defects as basis for venous thrombosis

21 January 2018

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Structure/function analyses of recombinant variants of human factor Xa: factor Xa incorporation into prothrombinase on the thrombin-activated platelet surface is not mimicked by synthetic phospholipid vesicles.

21 January 2018

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The Ca2+ ion and membrane binding structure of the Gla domain of Ca-prothrombin fragment 1

21 January 2018

1 reference

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Structural integrity of the gamma-carboxyglutamic acid domain of human blood coagulation factor IXa Is required for its binding to cofactor VIIIa

21 January 2018

1 reference

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Use of protein-C concentrate, heparin, and haemodiafiltration in meningococcus-induced purpura fulminans

21 January 2018

1 reference

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Nonenzymatic anticoagulant activity of the mutant serine protease Ser360Ala-activated protein C mediated by factor Va

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.273.47.31086

1 reference

25 May 2018

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25 May 2018