(Q54196963)

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Blockade of interleukin 6 signalling ameliorates systemic insulin resistance through upregulation of glucose uptake in skeletal muscle and improves hepatic steatosis in high-fat diet fed mice.

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scholarly article

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/25066281

Blockade of interleukin 6 signalling ameliorates systemic insulin resistance through upregulation of glucose uptake in skeletal muscle and improves hepatic steatosis in high-fat diet fed mice. (English)

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/25066281

insulin resistance

1 reference

based on heuristic

inferred from title

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based on heuristic

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author name string

Kanji Yamaguchi

1

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/25066281

Takeshi Nishimura

2

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/25066281

Hiroshi Ishiba

3

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/25066281

Yuya Seko

4

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/25066281

Akira Okajima

5

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/25066281

Hideki Fujii

6

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/25066281

Nozomi Tochiki

7

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/25066281

Atsushi Umemura

8

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/25066281

Michihisa Moriguchi

9

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/25066281

Yoshio Sumida

10

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/25066281

Hironori Mitsuyoshi

11

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/25066281

Kohichiroh Yasui

12

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/25066281

Masahito Minami

13

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/25066281

Takeshi Okanoue

14

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/25066281

Yoshito Itoh

15

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/25066281

publication date

12 August 2014

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Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/25066281

Liver International

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Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/25066281

35

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Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/25066281

2

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Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/25066281

550-561

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Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/25066281

The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

Mechanisms linking obesity to insulin resistance and type 2 diabetes

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

Inflammatory mechanisms in the regulation of insulin resistance

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

Review: The role of insulin resistance in nonalcoholic fatty liver disease

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

Increased hepatic and circulating interleukin-6 levels in human nonalcoholic steatohepatitis

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

Differential effects of interleukin-6 and -10 on skeletal muscle and liver insulin action in vivo

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

Interleukin-6 induces cellular insulin resistance in hepatocytes

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

Interleukin-6 depletion selectively improves hepatic insulin action in obesity

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

Muscle as an endocrine organ: focus on muscle-derived interleukin-6.

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

Beneficial health effects of exercise--the role of IL-6 as a myokine

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

Paradoxical effects of short- and long-term interleukin-6 exposure on liver injury and repair.

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

Short-term infusion of interleukin-6 does not induce insulin resistance in vivo or impair insulin signalling in rats

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

Sites and mechanisms of insulin resistance in nonobese, nondiabetic patients with chronic hepatitis C.

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice.

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

The IL-6-gp130-STAT3 pathway in hepatocytes triggers liver protection in T cell-mediated liver injury

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

Interleukin-6 protects against Fas-mediated death by establishing a critical level of anti-apoptotic hepatic proteins FLIP, Bcl-2, and Bcl-xL.

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

In vitro interleukin-6 treatment prevents mortality associated with fatty liver transplants in rats

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

Interleukin-6-deficient mice develop mature-onset obesity

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

Blockade of interleukin-6 signaling enhances hepatic steatosis but improves liver injury in methionine choline-deficient diet-fed mice

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis.

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes.

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

Adiponectin gene expression and secretion is inhibited by interleukin-6 in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

Integration of hormonal and nutrient signals that regulate leptin synthesis and secretion

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

Leptin activates AMP-activated protein kinase in hepatic cells via a JAK2-dependent pathway

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

The role of muscle insulin resistance in the pathogenesis of atherogenic dyslipidemia and nonalcoholic fatty liver disease associated with the metabolic syndrome.

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

Skeletal muscle insulin resistance promotes increased hepatic de novo lipogenesis, hyperlipidemia, and hepatic steatosis in the elderly

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

Synergistic interaction of dietary cholesterol and dietary fat in inducing experimental steatohepatitis

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

Interleukin-6 Directly Increases Glucose Metabolism in Resting Human Skeletal Muscle

1 reference

https://api.crossref.org/works/10.1111%2FLIV.12645

21 January 2018

Identifiers

10.1111/LIV.12645

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/25066281

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/25066281

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