(Q54197626)

26 May 2018

title

Innate IFN-γ promotes development of experimental autoimmune encephalomyelitis: a role for NK cells and M1 macrophages. (English)

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26 May 2018

experimental autoimmune encephalomyelitis

main subject

macrophage

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0 references

author

Marina A Lynch

4

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26 May 2018

Kingston H Mills

5

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26 May 2018

author name string

Lara S Dungan

1

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26 May 2018

Niamh C McGuinness

2

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26 May 2018

Louis Boon

3

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26 May 2018

language of work or name

English

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publication date

19 August 2014

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26 May 2018

European Journal of Immunology

published in

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26 May 2018

volume

44

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26 May 2018

issue

10

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26 May 2018

page(s)

2903-2917

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26 May 2018

Exacerbations of multiple sclerosis in patients treated with gamma interferon

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1 reference

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IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition.

21 January 2018

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Experimental autoimmune encephalitis and inflammation in the absence of interleukin-12

21 January 2018

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IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

21 January 2018

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Effect of anti-interferon-gamma and anti-interleukin-2 monoclonal antibody treatment on the development of actively and passively induced experimental allergic encephalomyelitis in the SJL/J mouse.

21 January 2018

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Highly polarized Th17 cells induce EAE via a T-bet independent mechanism

21 January 2018

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Cutting edge: Th1 cells facilitate the entry of Th17 cells to the central nervous system during experimental autoimmune encephalomyelitis

21 January 2018

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Integrins and T cell-mediated immunity

21 January 2018

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How do immune cells overcome the blood-brain barrier in multiple sclerosis?

21 January 2018

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Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin.

21 January 2018

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A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis

21 January 2018

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Th17 lymphocytes traffic to the central nervous system independently of α4 integrin expression during EAE

21 January 2018

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Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity.

21 January 2018

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21 January 2018

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Regulation of experimental autoimmune encephalomyelitis by natural killer (NK) cells

21 January 2018

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Regulation of activated CD4+ T cells by NK cells via the Qa-1-NKG2A inhibitory pathway.

21 January 2018

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Altered M1/M2 activation patterns of monocytes in severe relapsing experimental rat model of multiple sclerosis. Amelioration of clinical status by M2 activated monocyte administration.

21 January 2018

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The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF.

21 January 2018

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RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation.

21 January 2018

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Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

21 January 2018

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Interferon-gamma in progression to chronic demyelination and neurological deficit following acute EAE

21 January 2018

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7 January 2021

IL-12p35-deficient mice are susceptible to experimental autoimmune encephalomyelitis: evidence for redundancy in the IL-12 system in the induction of central nervous system autoimmune demyelination

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7 January 2021

Induction of experimental autoimmune encephalomyelitis in IL-12 receptor-beta 2-deficient mice: IL-12 responsiveness is not required in the pathogenesis of inflammatory demyelination in the central nervous system

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https://api.crossref.org/works/10.1002%2FEJI.201444612

7 January 2021

IL-18 directs autoreactive T cells and promotes autodestruction in the central nervous system via induction of IFN-gamma by NK cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444612

7 January 2021

Therapeutic potential of targeting IL-17

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201444612

7 January 2021

Identifiers

DOI

10.1002/EJI.201444612

1 reference

26 May 2018

PubMed ID

25056715

1 reference

26 May 2018