(Q54236068)

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Decreased tyrosine kinase activity in partially purified insulin receptors from muscle of young, non-obese first degree relatives of patients with type 2 (non-insulin-dependent) diabetes mellitus.

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scholarly article

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/8395436

Decreased tyrosine kinase activity in partially purified insulin receptors from muscle of young, non-obese first degree relatives of patients with type 2 (non-insulin-dependent) diabetes mellitus. (English)

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/8395436

type 2 diabetes

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author name string

A Handberg

1

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/8395436

A Vaag

2

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/8395436

J Vinten

3

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/8395436

H Beck-Nielsen

4

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/8395436

publication date

1 July 1993

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Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/8395436

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/8395436

36

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Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/8395436

7

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Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/8395436

668-674

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/8395436

https://scigraph.springernature.com/pub.10.1007/bf00404079

0 references

A defective intramolecular autoactivation cascade may cause the reduced kinase activity of the skeletal muscle insulin receptor from patients with non-insulin-dependent diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo stimulation of the insulin receptor kinase in human skeletal muscle. Correlation with insulin-stimulated glucose disposal during euglycemic clamp studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased expression of glucose transporter in muscle from insulin-resistant patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversibility of defective adipocyte insulin receptor kinase activity in non-insulin-dependent diabetes mellitus. Effect of weight loss

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective insulin receptor tyrosine kinase in human skeletal muscle in obesity and type 2 (non-insulin-dependent) diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-sensitive tyrosine kinase: relationship with in vivo insulin action in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced glycogen synthase activity in skeletal muscle from obese patients with and without type 2 (non-insulin-dependent) diabetes mellitus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Concordance for type 2 (non-insulin-dependent) diabetes mellitus in male twins

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased insulin concentrations in nondiabetic offspring of diabetic parents

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the gene sequences of the insulin receptor and the insulin-sensitive glucose transporter (GLUT-4) in patients with common-type non-insulin-dependent diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Receptor and postreceptor defects contribute to the insulin resistance in noninsulin-dependent diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-receptor autophosphorylation and endogenous substrate phosphorylation in human adipocytes from control, obese, and NIDDM subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Normal insulin-receptor cDNA sequence in Pima Indians with NIDDM

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired glucose tolerance as a disorder of insulin action. Longitudinal and cross-sectional studies in Pima Indians.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin receptor kinase in human skeletal muscle from obese subjects with and without noninsulin dependent diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of free fatty acid metabolism in the pathogenesis of insulin resistance in obesity and noninsulin-dependent diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diabetes mellitus in the Pima Indians: incidence, risk factors and pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence against altered expression of GLUT1 or GLUT4 in skeletal muscle of patients with obesity or NIDDM.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased insulin activation of glycogen synthase in skeletal muscles in young nonobese Caucasian first-degree relatives of patients with non-insulin-dependent diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of insulin resistance in non-insulin-dependent (type II) diabetes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early metabolic defects in persons at increased risk for non-insulin-dependent diabetes mellitus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lilly lecture 1987. The triumvirate: beta-cell, muscle, liver. A collusion responsible for NIDDM.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A model for the quaternary structure of human placental insulin receptor deduced from electron microscopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Banting lecture 1990. Beta-cells in type II diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin resistance in type 2 (non-insulin-dependent) diabetic patients and their relatives is not associated with a defect in the expression of the insulin-responsive glucose transporter (GLUT-4) gene in human skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The molecular mechanism by which insulin stimulates glycogen synthesis in mammalian skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influences of glucose loading and of injected insulin on hepatic glucose output

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin secretion and action in noninsulin-dependent diabetes mellitus. Is insulin resistance secondary to hypoinsulinemia?

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Postreceptor effects of sulfonylurea on skeletal muscle glycogen synthase activity in type II diabetic patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The natural history of impaired glucose tolerance in the Pima Indians.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal Regulation of Protein Tyrosine Phosphatase Activities in Skeletal Muscle of Insulin-Resistant Humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rat insulin-receptor kinase activity correlates with in vivo insulin action

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic studies in unaffected co-twins of non-insulin-dependent diabetics.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of insulin regulatable glucose transporters in skeletal muscle from type 2 (non-insulin-dependent) diabetic patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitation of muscle glycogen synthesis in normal subjects and subjects with non-insulin-dependent diabetes by 13C nuclear magnetic resonance spectroscopy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of defective insulin-receptor kinase activity in NIDDM. Evidence for two receptor populations

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like and insulin-inhibitory effects of monoclonal antibodies for different epitopes on the human insulin receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The amino acid sequence of the insulin receptor is normal in an insulin-resistant Pima Indian

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired autophosphorylation of insulin receptors from abdominal skeletal muscles in nonobese subjects with NIDDM.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Slow glucose removal rate and hyperinsulinemia precede the development of type II diabetes in the offspring of diabetic parents.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The insulin receptor: signalling mechanism and contribution to the pathogenesis of insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A monoclonal anti-peptide antibody reacting with the insulin receptor β-subunit. Characterization of the antibody and its epitope and use in immunoaffinity purification of intact receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/8395436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF00404079

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/8395436

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/8395436

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