(Q54307659)

27 May 2018

title

Mechanisms and fitness costs of tigecycline resistance in Escherichia coli. (English)

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27 May 2018

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Marius Linkevicius

1

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27 May 2018

Linus Sandegren

series ordinal

2

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27 May 2018

Dan I Andersson

series ordinal

3

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27 May 2018

language of work or name

English

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publication date

9 July 2013

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27 May 2018

Journal of Antimicrobial Chemotherapy

published in

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27 May 2018

volume

68

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27 May 2018

issue

12

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27 May 2018

page(s)

2809-2819

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27 May 2018

Synthesis and structure-activity relationship of novel glycylcycline derivatives leading to the discovery of GAR-936.

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Functional, biophysical, and structural bases for antibacterial activity of tigecycline

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Structural basis for potent inhibitory activity of the antibiotic tigecycline during protein synthesis

21 January 2018

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Tigecycline: a new glycylcycline for treatment of serious infections

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Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study

21 January 2018

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The efficacy and safety of tigecycline for the treatment of complicated intra-abdominal infections: analysis of pooled clinical trial data

21 January 2018

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The efficacy and safety of tigecycline in the treatment of skin and skin-structure infections: results of 2 double-blind phase 3 comparison studies with vancomycin-aztreonam

21 January 2018

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Integrated results of 2 phase 3 studies comparing tigecycline and levofloxacin in community-acquired pneumonia

21 January 2018

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Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance

21 January 2018

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Effects of efflux transporter genes on susceptibility of Escherichia coli to tigecycline (GAR-936).

21 January 2018

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A novel glycylcycline, 9-(N,N-dimethylglycylamido)-6-demethyl-6-deoxytetracycline, is neither transported nor recognized by the transposon Tn10-encoded metal-tetracycline/H+ antiporter

21 January 2018

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Structural basis for TetM-mediated tetracycline resistance

21 January 2018

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The emergence of clinical resistance to tigecycline

21 January 2018

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Efflux-mediated resistance to tigecycline (GAR-936) in Pseudomonas aeruginosa PAO1.

21 January 2018

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AcrAB multidrug efflux pump is associated with reduced levels of susceptibility to tigecycline (GAR-936) in Proteus mirabilis

21 January 2018

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AcrAB efflux pump plays a role in decreased susceptibility to tigecycline in Morganella morganii

21 January 2018

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Influence of transcriptional activator RamA on expression of multidrug efflux pump AcrAB and tigecycline susceptibility in Klebsiella pneumoniae

21 January 2018

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RamA, a transcriptional regulator, and AcrAB, an RND-type efflux pump, are associated with decreased susceptibility to tigecycline in Enterobacter cloacae.

21 January 2018

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MarA-mediated overexpression of the AcrAB efflux pump results in decreased susceptibility to tigecycline in Escherichia coli

21 January 2018

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Combined ramR mutation and presence of a Tn1721-associated tet(A) variant in a clinical isolate of Salmonella enterica serovar Hadar resistant to tigecycline

21 January 2018

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AdeIJK, a resistance-nodulation-cell division pump effluxing multiple antibiotics in Acinetobacter baumannii

21 January 2018

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A novel MATE family efflux pump contributes to the reduced susceptibility of laboratory-derived Staphylococcus aureus mutants to tigecycline

21 January 2018

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Efflux pumps may play a role in tigecycline resistance in Burkholderia species.

21 January 2018

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Tigecycline is modified by the flavin-dependent monooxygenase TetX.

21 January 2018

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Investigation of the prevalence of tetQ, tetX and tetX1 genes in Bacteroides strains with elevated tigecycline minimum inhibitory concentrations

21 January 2018

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Contemporary causes of skin and soft tissue infections in North America, Latin America, and Europe: report from the SENTRY Antimicrobial Surveillance Program (1998-2004).

21 January 2018

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Incidence and antimicrobial susceptibility of Escherichia coli and Klebsiella pneumoniae with extended-spectrum beta-lactamases in community- and hospital-associated intra-abdominal infections in Europe: results of the 2008 Study for Monitoring Anti

21 January 2018

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The CTX-M beta-lactamase pandemic.

21 January 2018

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Global spread of Carbapenemase-producing Enterobacteriaceae

21 January 2018

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The biological cost of antibiotic resistance

21 January 2018

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The biological cost of mutational antibiotic resistance: any practical conclusions?

21 January 2018

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The distribution of the numbers of mutants in bacterial populations

21 January 2018

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One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products

21 January 2018

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An efficient recombination system for chromosome engineering in Escherichia coli

21 January 2018

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https://api.crossref.org/works/10.1093%2FJAC%2FDKT263

IS186 insertion at a hot spot in the lon promoter as a basis for lon protease deficiency of Escherichia coli B: identification of a consensus target sequence for IS186 transposition

21 January 2018

1 reference

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Role for tandem duplication and lon protease in AcrAB-TolC- dependent multiple antibiotic resistance (Mar) in an Escherichia coli mutant without mutations in marRAB or acrRAB.

21 January 2018

1 reference

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Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications

21 January 2018

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Nitrofurantoin resistance mechanism and fitness cost in Escherichia coli

21 January 2018

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Proteolytic degradation of Escherichia coli transcription activators SoxS and MarA as the mechanism for reversing the induction of the superoxide (SoxRS) and multiple antibiotic resistance (Mar) regulons

21 January 2018

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Binding of purified multiple antibiotic-resistance repressor protein (MarR) to mar operator sequences

21 January 2018

1 reference

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Insertion of inverted Ter sites into the terminus region of the Escherichia coli chromosome delays completion of DNA replication and disrupts the cell cycle.

21 January 2018

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https://api.crossref.org/works/10.1093%2FJAC%2FDKT263

The local repressor AcrR plays a modulating role in the regulation of acrAB genes of Escherichia coli by global stress signals

21 January 2018

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https://api.crossref.org/works/10.1093%2FJAC%2FDKT263

Emergence of AcrAB-mediated tigecycline resistance in a clinical isolate of Enterobacter cloacae during ciprofloxacin treatment

21 January 2018

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https://api.crossref.org/works/10.1093%2FJAC%2FDKT263

Biosynthesis pathway of ADP-L-glycero-beta-D-manno-heptose in Escherichia coli

21 January 2018

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https://api.crossref.org/works/10.1093%2FJAC%2FDKT263

Penetration of lipophilic agents with multiple protonation sites into bacterial cells: tetracyclines and fluoroquinolones as examples

21 January 2018

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https://api.crossref.org/works/10.1093%2FJAC%2FDKT263

Biological costs and mechanisms of fosfomycin resistance in Escherichia coli

21 January 2018

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https://api.crossref.org/works/10.1093%2FJAC%2FDKT263

Effect of activated nitrofurans on DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT263

Model for regulation of Escherichia coli DNA repair functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT263

AdeABC multidrug efflux pump is associated with decreased susceptibility to tigecycline in Acinetobacter calcoaceticus–Acinetobacter baumannii complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT263

21 January 2018

Identifiers

DOI

10.1093/JAC/DKT263

1 reference

27 May 2018

1 reference

27 May 2018