(Q54333338)

27 May 2018

title

FIP200 inhibits β-catenin-mediated transcription by promoting APC-independent β-catenin ubiquitination. (English)

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27 May 2018

main subject

protein ubiquitination

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J D Choi

1

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27 May 2018

M Ryu

2

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27 May 2018

M Ae Park

3

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27 May 2018

G Jeong

4

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27 May 2018

J-S Lee

5

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27 May 2018

language of work or name

English

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publication date

2 July 2012

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27 May 2018

published in

Oncogene

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27 May 2018

volume

32

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27 May 2018

issue

19

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27 May 2018

page(s)

2421-2432

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27 May 2018

https://scigraph.springernature.com/pub.10.1038/onc.2012.262

exact match

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cites work

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Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice

21 January 2018

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Linking colorectal cancer to Wnt signaling

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The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell.

21 January 2018

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The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin.

21 January 2018

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Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation

21 January 2018

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Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

21 January 2018

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FIP200, a key signaling node to coordinately regulate various cellular processes

21 January 2018

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Suppression of Pyk2 kinase and cellular activities by FIP200

21 January 2018

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Regulation of focal adhesion kinase by a novel protein inhibitor FIP200

21 January 2018

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Identification of FIP200 interaction with the TSC1-TSC2 complex and its role in regulation of cell size control

21 January 2018

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Role of FIP200 in cardiac and liver development and its regulation of TNFalpha and TSC-mTOR signaling pathways

21 January 2018

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Identification of RB1CC1, a novel human gene that can induce RB1 in various human cells

21 January 2018

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Spatial interplay between PIASy and FIP200 in the regulation of signal transduction and transcriptional activity

21 January 2018

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Isolation, characterization and mapping of the mouse and human RB1CC1 genes

21 January 2018

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Truncating mutations of RB1CC1 in human breast cancer

21 January 2018

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Mechanism of cell cycle regulation by FIP200 in human breast cancer cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.262

Suppression of autophagy by FIP200 deletion inhibits mammary tumorigenesis

21 January 2018

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Suppression of autophagy by FIP200 deletion impairs DNA damage repair and increases cell death upon treatments with anticancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.262

FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells

21 January 2018

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RB1CC1 protein positively regulates transforming growth factor-beta signaling through the modulation of Arkadia E3 ubiquitin ligase activity

21 January 2018

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A ubiquitin-binding motif in the translesion DNA polymerase Rev1 mediates its essential functional interaction with ubiquitinated proliferating cell nuclear antigen in response to DNA damage

21 January 2018

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Ubiquitin-binding motif of human DNA polymerase eta is required for correct localization

21 January 2018

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Ubiquitin-binding domains and their role in the DNA damage response

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Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation

21 January 2018

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β-catenin is dynamically stored and cleared in multiple myeloma by the proteasome-aggresome-autophagosome-lysosome pathway.

21 January 2018

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ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy

21 January 2018

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Neural-specific deletion of FIP200 leads to cerebellar degeneration caused by increased neuronal death and axon degeneration

21 January 2018

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FIP200 is required for the cell-autonomous maintenance of fetal hematopoietic stem cells

21 January 2018

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RB1CC1 activates RB1 pathway and inhibits proliferation and cologenic survival in human cancer

21 January 2018

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beta-catenin signaling and cancer

21 January 2018

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Siah-1 mediates a novel beta-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein

21 January 2018

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Tumor suppressor PTEN inhibits nuclear accumulation of beta-catenin and T cell/lymphoid enhancer factor 1-mediated transcriptional activation

21 January 2018

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Adenomatous polyposis coli (APC)-independent regulation of beta-catenin degradation via a retinoid X receptor-mediated pathway

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.262

Inactivation of FIP200 leads to inflammatory skin disorder, but not tumorigenesis, in conditional knock-out mouse models

21 January 2018

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Jade-1 inhibits Wnt signalling by ubiquitylating beta-catenin and mediates Wnt pathway inhibition by pVHL

21 January 2018

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A system for stable expression of short interfering RNAs in mammalian cells

21 January 2018

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Acetyltransferase p300 regulates NBS1-mediated DNA damage response

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.262

SUMO1 negatively regulates BRCA1-mediated transcription, via modulation of promoter occupancy

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.262

hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.262

Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.262

Nuclear beta-catenin displays GSK-3beta- and APC-independent proteasome sensitivity in melanoma cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.262

31 March 2020

Identifiers

DOI

10.1038/ONC.2012.262

1 reference

27 May 2018

PubMed ID

22751121

1 reference

27 May 2018