(Q54345641)

English

A multicenter phase 1 study of PX-866 and cetuximab in patients with metastatic colorectal carcinoma or recurrent/metastatic squamous cell carcinoma of the head and neck.

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scholarly article

1 reference

Europe PubMed Central

28 May 2018

http://europepmc.org/abstract/MED/24916771

A multicenter phase 1 study of PX-866 and cetuximab in patients with metastatic colorectal carcinoma or recurrent/metastatic squamous cell carcinoma of the head and neck. (English)

1 reference

Europe PubMed Central

28 May 2018

http://europepmc.org/abstract/MED/24916771

1 reference

based on heuristic

inferred from title

metastatic colorectal carcinoma

1 reference

based on heuristic

inferred from title

author name string

Daniel W Bowles

1

1 reference

Europe PubMed Central

28 May 2018

http://europepmc.org/abstract/MED/24916771

Neil Senzer

2

1 reference

Europe PubMed Central

28 May 2018

http://europepmc.org/abstract/MED/24916771

Diana Hausman

3

1 reference

Europe PubMed Central

28 May 2018

http://europepmc.org/abstract/MED/24916771

Scott Peterson

4

1 reference

Europe PubMed Central

28 May 2018

http://europepmc.org/abstract/MED/24916771

Alex Vo

5

1 reference

Europe PubMed Central

28 May 2018

http://europepmc.org/abstract/MED/24916771

Luke Walker

6

1 reference

Europe PubMed Central

28 May 2018

http://europepmc.org/abstract/MED/24916771

Roger B Cohen

7

1 reference

Europe PubMed Central

28 May 2018

http://europepmc.org/abstract/MED/24916771

Antonio Jimeno

8

1 reference

Europe PubMed Central

28 May 2018

http://europepmc.org/abstract/MED/24916771

publication date

12 June 2014

1 reference

Europe PubMed Central

28 May 2018

http://europepmc.org/abstract/MED/24916771

Investigational New Drugs

1 reference

Europe PubMed Central

28 May 2018

http://europepmc.org/abstract/MED/24916771

32

1 reference

Europe PubMed Central

28 May 2018

http://europepmc.org/abstract/MED/24916771

6

1 reference

Europe PubMed Central

28 May 2018

http://europepmc.org/abstract/MED/24916771

1197-1203

1 reference

Europe PubMed Central

28 May 2018

http://europepmc.org/abstract/MED/24916771

https://scigraph.springernature.com/pub.10.1007/s10637-014-0124-3

0 references

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1 reference

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The PI3K pathway as drug target in human cancer

1 reference

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Somatic mutations in p85alpha promote tumorigenesis through class IA PI3K activation

1 reference

https://api.crossref.org/works/10.1007%2FS10637-014-0124-3

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Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1

1 reference

https://api.crossref.org/works/10.1007%2FS10637-014-0124-3

21 January 2018

Frequent mutation of the PI3K pathway in head and neck cancer defines predictive biomarkers

1 reference

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The PTEN-PI3K pathway: of feedbacks and cross-talks

1 reference

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1 reference

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New phosphatidylinositol 3-kinase inhibitors for cancer

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21 January 2018

Synthesis and biological evaluation of synthetic viridins derived from C(20)-heteroalkylation of the steroidal PI-3-kinase inhibitor wortmannin

1 reference

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21 January 2018

The phosphatidylinositol-3-kinase inhibitor PX-866 overcomes resistance to the epidermal growth factor receptor inhibitor gefitinib in A-549 human non-small cell lung cancer xenografts

1 reference

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21 January 2018

Cellular and in vivo activity of a novel PI3K inhibitor, PX-866, against human glioblastoma

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Targeting the HER-kinase axis in cancer

1 reference

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Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma

1 reference

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K-ras mutations and benefit from cetuximab in advanced colorectal cancer.

1 reference

https://api.crossref.org/works/10.1007%2FS10637-014-0124-3

21 January 2018

Platinum-based chemotherapy plus cetuximab in head and neck cancer

1 reference

https://api.crossref.org/works/10.1007%2FS10637-014-0124-3

21 January 2018

Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis

1 reference

https://api.crossref.org/works/10.1007%2FS10637-014-0124-3

21 January 2018

Can we accurately report PTEN status in advanced colorectal cancer?

1 reference

https://api.crossref.org/works/10.1007%2FS10637-014-0124-3

21 January 2018

The quest to overcome resistance to EGFR-targeted therapies in cancer

1 reference

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21 January 2018

Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors

1 reference

https://api.crossref.org/works/10.1007%2FS10637-014-0124-3

21 January 2018

A multicenter phase 1 study of PX-866 in combination with docetaxel in patients with advanced solid tumours.

1 reference

https://api.crossref.org/works/10.1007%2FS10637-014-0124-3

21 January 2018

Skin toxicity evaluation protocol with panitumumab (STEPP), a phase II, open-label, randomized trial evaluating the impact of a pre-Emptive Skin treatment regimen on skin toxicities and quality of life in patients with metastatic colorectal cancer

1 reference

https://api.crossref.org/works/10.1007%2FS10637-014-0124-3

21 January 2018

Phase I, dose-escalation study of BKM120, an oral pan-Class I PI3K inhibitor, in patients with advanced solid tumors

1 reference

https://api.crossref.org/works/10.1007%2FS10637-014-0124-3

21 January 2018

PIK3CA mutations in patients with advanced cancers treated with PI3K/AKT/mTOR axis inhibitors

1 reference

https://api.crossref.org/works/10.1007%2FS10637-014-0124-3

21 January 2018

PI3K/AKT/mTOR inhibitors in patients with breast and gynecologic malignancies harboring PIK3CA mutations

1 reference

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21 January 2018

Open-Label, Uncontrolled, Multicenter Phase II Study to Evaluate the Efficacy and Toxicity of Cetuximab As a Single Agent in Patients With Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck Who Failed to Respond to Platinum-Base

1 reference

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21 January 2018

Comprehensive molecular characterization of human colon and rectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24916771

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A multicenter phase I trial of PX-866, an oral irreversible phosphatidylinositol 3-kinase inhibitor, in patients with advanced solid tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/24916771

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acquired resistance to EGFR tyrosine kinase inhibitors in cancer cells is mediated by loss of IGF-binding proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/24916771

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S10637-014-0124-3

1 reference

Europe PubMed Central

28 May 2018

http://europepmc.org/abstract/MED/24916771

release_wnxn77c3lbek7ngrao45jsbjta

1 reference

https://api.fatcat.wiki/v0/release/wnxn77c3lbek7ngrao45jsbjta

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

28 May 2018

http://europepmc.org/abstract/MED/24916771

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