(Q54352868)

28 May 2018

title

mTORC1 is involved in hypoxia-induced pulmonary hypertension through the activation of Notch3. (English)

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28 May 2018

main subject

hypoxia

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pulmonary hypertension

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Wang Wang

1

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28 May 2018

Jie Liu

2

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28 May 2018

Aiping Ma

3

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28 May 2018

Ran Miao

4

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28 May 2018

Yuling Jin

5

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28 May 2018

Hongbing Zhang

6

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28 May 2018

Kaifeng Xu

7

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28 May 2018

Chen Wang

8

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28 May 2018

Jun Wang

9

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28 May 2018

publication date

1 December 2014

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28 May 2018

Journal of Cellular Physiology

published in

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28 May 2018

volume

229

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28 May 2018

issue

12

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28 May 2018

page(s)

2117-2125

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28 May 2018

Ribosomal S6 kinase signaling and the control of translation

cites work

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Notch signalling in smooth muscle cells during development and disease

21 January 2018

1 reference

Activation of phosphatidylinositol 3-kinase, Akt, and mammalian target of rapamycin is necessary for hypoxia-induced pulmonary artery adventitial fibroblast proliferation

21 January 2018

1 reference

Hypoxia- and non-hypoxia-related pulmonary hypertension - established and new therapies.

21 January 2018

1 reference

Mammalian target of rapamycin complex 2 (mTORC2) coordinates pulmonary artery smooth muscle cell metabolism, proliferation, and survival in pulmonary arterial hypertension

21 January 2018

1 reference

Rapamycin reverses pulmonary artery smooth muscle cell proliferation in pulmonary hypertension

21 January 2018

1 reference

Activation of endothelin-1 receptor signaling pathways is associated with neointima formation, neoangiogenesis and irreversible pulmonary artery hypertension in patients with congenital heart disease

21 January 2018

1 reference

Pivotal role for endothelial tetrahydrobiopterin in pulmonary hypertension

21 January 2018

1 reference

The canonical Notch signaling pathway: unfolding the activation mechanism

21 January 2018

1 reference

mTOR is required for pulmonary arterial vascular smooth muscle cell proliferation under chronic hypoxia

21 January 2018

1 reference

mTOR signaling in growth control and disease

21 January 2018

1 reference

Hypoxia-induced endothelial proliferation requires both mTORC1 and mTORC2

21 January 2018

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Notch3 signaling promotes the development of pulmonary arterial hypertension

21 January 2018

1 reference

Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade

21 January 2018

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40-O-(2-hydroxyethyl)-rapamycin attenuates pulmonary arterial hypertension and neointimal formation in rats

21 January 2018

1 reference

Inhibition of mTOR attenuates store-operated Ca2+ entry in cells from endarterectomized tissues of patients with chronic thromboembolic pulmonary hypertension

21 January 2018

1 reference

Rapamycin attenuates hypoxia-induced pulmonary vascular remodeling and right ventricular hypertrophy in mice

21 January 2018

1 reference

Clinical perspective of hypoxia-mediated pulmonary hypertension

21 January 2018

1 reference

Notch signaling change in pulmonary vascular remodeling in rats with pulmonary hypertension and its implication for therapeutic intervention

21 January 2018

1 reference

Regulation of vascular morphogenesis by Notch signaling

21 January 2018

1 reference

Involvement of hypoxia-inducible factor 1 in pulmonary pathophysiology

21 January 2018

1 reference

Hypoxia-induced pulmonary vascular remodeling: cellular and molecular mechanisms

21 January 2018

1 reference

Notch signaling in pulmonary hypertension

21 January 2018

1 reference

Inhibition of SOC/Ca2+/NFAT pathway is involved in the anti-proliferative effect of sildenafil on pulmonary artery smooth muscle cells

21 January 2018

1 reference

Dramatic improvement in pulmonary hypertension with rapamycin

21 January 2018

1 reference

Prevention of pulmonary hypertension by Angiotensin-converting enzyme 2 gene transfer.

21 January 2018

1 reference

Activation of mTORC2 by association with the ribosome

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/JCP.24670

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28 May 2018

PubMed ID

24825564

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28 May 2018