(Q54369374)

English

Phosphorylation of Ser45 and Ser59 of αB-crystallin and p38/extracellular regulated kinase activity determine αB-crystallin-mediated protection of rat brain astrocytes from C2-ceramide- and staurosporine-induced cell death.

scientific article published on 17 June 2011

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

28 May 2018

http://europepmc.org/abstract/MED/21615407

Phosphorylation of Ser45 and Ser59 of αB-crystallin and p38/extracellular regulated kinase activity determine αB-crystallin-mediated protection of rat brain astrocytes from C2-ceramide- and staurosporine-induced cell death. (English)

1 reference

Europe PubMed Central

PubMed publication ID

28 May 2018

http://europepmc.org/abstract/MED/21615407

0 references

phosphorylation

1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

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based on heuristic

inferred from title

author name string

Rongyu Li

1

1 reference

Europe PubMed Central

PubMed publication ID

28 May 2018

http://europepmc.org/abstract/MED/21615407

Georg Reiser

2

1 reference

Europe PubMed Central

PubMed publication ID

28 May 2018

http://europepmc.org/abstract/MED/21615407

language of work or name

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publication date

17 June 2011

1 reference

Europe PubMed Central

PubMed publication ID

28 May 2018

http://europepmc.org/abstract/MED/21615407

number of pages

11

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based on heuristic

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Journal of Neurochemistry

1 reference

Europe PubMed Central

PubMed publication ID

28 May 2018

http://europepmc.org/abstract/MED/21615407

118

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Europe PubMed Central

PubMed publication ID

28 May 2018

http://europepmc.org/abstract/MED/21615407

3

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Europe PubMed Central

PubMed publication ID

28 May 2018

http://europepmc.org/abstract/MED/21615407

354-364

1 reference

Europe PubMed Central

PubMed publication ID

28 May 2018

http://europepmc.org/abstract/MED/21615407

The molecular chaperone alphaA-crystallin enhances lens epithelial cell growth and resistance to UVA stress

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Differential protective activity of alpha A- and alphaB-crystallin in lens epithelial cells.

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Phosphorylation of alphaB-crystallin alters chaperone function through loss of dimeric substructure

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Activation of protease-activated receptor (PAR)-1, PAR-2, and PAR-4 stimulates IL-6, IL-8, and prostaglandin E2 release from human respiratory epithelial cells

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alpha-crystallin: a review of its structure and function

1 reference

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Agonists of proteinase-activated receptor-2 stimulate upregulation of intercellular cell adhesion molecule-1 in primary human keratinocytes via activation of NF-kappa B.

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Characterization of proteinase-activated receptor 2 signalling and expression in rat hippocampal neurons and astrocytes

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Characterization of alpha-crystallin-plasma membrane binding

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Proteinase-activated receptor-2: physiological and pathophysiological roles

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Characterization of protease-activated receptor-2 immunoreactivity in normal human tissues

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Protease-activated receptor 2 in colon cancer: trypsin-induced MAPK phosphorylation and cell proliferation are mediated by epidermal growth factor receptor transactivation

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AlphaB crystallin translocation and phosphorylation: signal transduction pathways and preconditioning in the isolated rat heart

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Proteinase-activated receptor 2 is an anti-inflammatory signal for colonic lamina propria lymphocytes in a mouse model of colitis

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Suppression of GFAP toxicity by alphaB-crystallin in mouse models of Alexander disease

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Activation of protease-activated receptor 2 stimulates proliferation and interleukin (IL)-6 and IL-8 secretion of endometriotic stromal cells

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alpha B-crystallin gene induction and phosphorylation by MKK6-activated p38. A potential role for alpha B-crystallin as a target of the p38 branch of the cardiac stress response

1 reference

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21 January 2018

Alpha-crystallin can function as a molecular chaperone

1 reference

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Phosphorylation of alphaB-crystallin in response to various types of stress.

1 reference

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Alpha B-crystallin is expressed in non-lenticular tissues and accumulates in Alexander's disease brain

1 reference

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Cellular distribution of alpha B-crystallin in non-lenticular tissues.

1 reference

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The small heat shock protein alpha B-crystallin negatively regulates cytochrome c- and caspase-8-dependent activation of caspase-3 by inhibiting its autoproteolytic maturation

1 reference

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21 January 2018

Ser-59 is the major phosphorylation site in alphaB-crystallin accumulated in the brains of patients with Alexander's disease

1 reference

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21 January 2018

Calcium-activated RAF/MEK/ERK signaling pathway mediates p53-dependent apoptosis and is abrogated by alpha B-crystallin through inhibition of RAS activation

1 reference

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21 January 2018

Alpha A-crystallin and alpha B-crystallin, newly identified interaction proteins of protease-activated receptor-2, rescue astrocytes from C2-ceramide- and staurosporine-induced cell death

1 reference

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21 January 2018

Human alphaA- and alphaB-crystallins prevent UVA-induced apoptosis through regulation of PKCalpha, RAF/MEK/ERK and AKT signaling pathways

1 reference

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21 January 2018

The role of intracellular Ca2+ in the regulation of proteinase-activated receptor-2 mediated nuclear factor kappa B signalling in keratinocytes

1 reference

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21 January 2018

alpha-Crystallin localizes to the leading edges of migrating lens epithelial cells

1 reference

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21 January 2018

Human alphaA- and alphaB-crystallins bind to Bax and Bcl-X(S) to sequester their translocation during staurosporine-induced apoptosis

1 reference

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21 January 2018

Molecular chaperone alpha-crystallin prevents detrimental effects of neuroinflammation

1 reference

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21 January 2018

Mimicking phosphorylation of alphaB-crystallin on serine-59 is necessary and sufficient to provide maximal protection of cardiac myocytes from apoptosis

1 reference

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Protective and therapeutic role for alphaB-crystallin in autoimmune demyelination

1 reference

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Evidence that protease-activated receptor-2 mediates trypsin-induced reversal of stellation in cultured rat astrocytes

1 reference

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Co-induction of alphaB-crystallin and MAPKAPK-2 in astrocytes in the penumbra after transient focal cerebral ischemia

1 reference

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Alpha-B-crystallin in neuropathology

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Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras.

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Protection against acute pancreatitis by activation of protease-activated receptor-2.

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A novel therapeutic target in various lung diseases: airway proteases and protease-activated receptors

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Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism

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Proteinase-activated receptors: transducers of proteinase-mediated signaling in inflammation and immune response.

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The small heat shock proteins and their role in human disease.

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Redistribution of GFAP and alphaB-crystallin after thermal stress in C6 glioma cell line.

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Thrombin signaling in the brain: the role of protease-activated receptors

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Four subtypes of protease-activated receptors, co-expressed in rat astrocytes, evoke different physiological signaling

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Proteinase-activated receptor-1 and -2 induce the release of chemokine GRO/CINC-1 from rat astrocytes via differential activation of JNK isoforms, evoking multiple protective pathways in brain

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Trypsin and trypsin-like proteases in the brain: proteolysis and cellular functions

1 reference

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Serine phosphorylation and suppression of apoptosis by the small heat shock protein alphaB-crystallin

1 reference

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21 January 2018

Alpha-crystallin expression affects microtubule assembly and prevents their aggregation

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A protective role for protease-activated receptors in the airways

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Identifiers

10.1111/J.1471-4159.2011.07317.X

1 reference

Europe PubMed Central

PubMed publication ID

28 May 2018

http://europepmc.org/abstract/MED/21615407

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 May 2018

http://europepmc.org/abstract/MED/21615407

ResearchGate publication ID

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