(Q54369988)

28 May 2018

title

Tgfβ/Alk5 signaling is required for shear stress induced klf2 expression in embryonic endothelial cells. (English)

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28 May 2018

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11

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28 May 2018

author name string

Anastasia D Egorova

1

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28 May 2018

Kim Van der Heiden

2

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28 May 2018

Simone Van de Pas

3

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28 May 2018

Peter Vennemann

4

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28 May 2018

Christian Poelma

5

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28 May 2018

Marco C DeRuiter

6

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28 May 2018

Marie-José T H Goumans

7

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28 May 2018

Adriana C Gittenberger-de Groot

8

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28 May 2018

Peter ten Dijke

9

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28 May 2018

Robert E Poelmann

10

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28 May 2018

publication date

20 May 2011

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28 May 2018

published in

Developmental Dynamics

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28 May 2018

volume

240

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28 May 2018

issue

7

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28 May 2018

page(s)

1670-1680

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28 May 2018

TGF-beta activates ERK5 in human renal epithelial cells

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1 reference

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Transitions in early embryonic atrioventricular valvular function correspond with changes in cushion biomechanics that are predictable by tissue composition.

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Heart valve development: regulatory networks in development and disease

21 January 2018

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Prolonged fluid shear stress induces a distinct set of endothelial cell genes, most specifically lung Krüppel-like factor (KLF2)

21 January 2018

1 reference

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Endothelial KLF2 links local arterial shear stress levels to the expression of vascular tone-regulating genes

21 January 2018

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Smad-dependent and Smad-independent pathways in TGF-beta family signalling

21 January 2018

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Lack of primary cilia primes shear-induced endothelial-to-mesenchymal transition.

21 January 2018

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KLF2 primes the antioxidant transcription factor Nrf2 for activation in endothelial cells

21 January 2018

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Biomechanical activation of vascular endothelium as a determinant of its functional phenotype.

21 January 2018

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Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors

21 January 2018

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Controlling the angiogenic switch: a balance between two distinct TGF-b receptor signaling pathways

21 January 2018

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Transforming growth factor beta-induced endothelial-to-mesenchymal transition: a switch to cardiac fibrosis?

21 January 2018

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21 January 2018

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The role of shear stress on ET-1, KLF2, and NOS-3 expression in the developing cardiovascular system of chicken embryos in a venous ligation model

21 January 2018

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A series of normal stages in the development of the chick embryo

21 January 2018

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A chicken model for DGCR6 as a modifier gene in the DiGeorge critical region.

21 January 2018

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Intracardiac fluid forces are an essential epigenetic factor for embryonic cardiogenesis

21 January 2018

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SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7

21 January 2018

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Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria

21 January 2018

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Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation

21 January 2018

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Abnormal angiogenesis but intact hematopoietic potential in TGF-beta type I receptor-deficient mice

21 January 2018

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TGF-beta receptor function in the endothelium.

21 January 2018

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Cellular mechanics and gene expression in blood vessels

21 January 2018

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ERK5/MAPK is activated by TGFbeta in hepatocytes and required for the GSK-3beta-mediated Snail protein stabilization.

21 January 2018

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Structural development of endocardial cushions

21 January 2018

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Multiple transforming growth factor-beta isoforms and receptors function during epithelial-mesenchymal cell transformation in the embryonic heart

21 January 2018

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TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4

21 January 2018

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Endothelial cilia are fluid shear sensors that regulate calcium signaling and nitric oxide production through polycystin-1

21 January 2018

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Integration of flow-dependent endothelial phenotypes by Kruppel-like factor 2

21 January 2018

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Measurements of the wall shear stress distribution in the outflow tract of an embryonic chicken heart.

21 January 2018

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Induction of endocardial cushion tissue in the avian heart is regulated, in part, by TGFbeta-3-mediated autocrine signaling.

21 January 2018

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Fluid shear stress and the vascular endothelium: for better and for worse

21 January 2018

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ERK5 and the regulation of endothelial cell function.

21 January 2018

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KLF2 Is a novel transcriptional regulator of endothelial proinflammatory activation

21 January 2018

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Transcriptional regulation of tissue-specific genes by the ERK5 mitogen-activated protein kinase

21 January 2018

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Vascular MADs: two novel MAD-related genes selectively inducible by flow in human vascular endothelium

21 January 2018

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Shear stress sustains atheroprotective endothelial KLF2 expression more potently than statins through mRNA stabilization.

21 January 2018

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In vivo micro particle image velocimetry measurements of blood-plasma in the embryonic avian heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.22660

Shear stress regulation of Krüppel-like factor 2 expression is flow pattern-specific

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.22660

Adaptation of the endothelium to fluid flow: in vitro analyses of gene expression and in vivo implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.22660

KLF2 transcription factor modulates blood vessel maturation through smooth muscle cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.22660

Endothelial-to-mesenchymal transition contributes to cardiac fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.22660

Changes in Shear Stress–Related Gene Expression After Experimentally Altered Venous Return in the Chicken Embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.22660

Primary cilia sensitize endothelial cells for fluid shear stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.22660

Deciphering the Endothelial Shear Stress Sensor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.22660

KLF2 suppresses TGF-beta signaling in endothelium through induction of Smad7 and inhibition of AP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.22660

7 January 2021

Increased ventricular preload is compensated by myocyte proliferation in normal and hypoplastic fetal chick left ventricle

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.22660

7 January 2021

KLF2 provokes a gene expression pattern that establishes functional quiescent differentiation of the endothelium

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.22660

7 January 2021

Unilateral vitelline vein ligation alters intracardiac blood flow patterns and morphogenesis in the chick embryo

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.22660

7 January 2021

Extraembryonic venous obstructions lead to cardiovascular malformations and can be embryolethal

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.22660

7 January 2021

Remodeling of chick embryonic ventricular myoarchitecture under experimentally changed loading conditions

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.22660

7 January 2021

Regional passive ventricular stress-strain relations during development of altered loads in chick embryo

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.22660

7 January 2021

Fluid shear stress stimulates big mitogen-activated protein kinase 1 (BMK1) activity in endothelial cells. Dependence on tyrosine kinases and intracellular calcium

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.22660

7 January 2021

Identifiers

DOI

10.1002/DVDY.22660

1 reference

28 May 2018

PubMed ID

21604321

1 reference

28 May 2018