(Q54400668)

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Production of novel lipopeptide antibiotics related to A54145 by Streptomyces fradiae mutants blocked in biosynthesis of modified amino acids and assignment of lptJ, lptK and lptL gene functions.

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Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/21102596

Production of novel lipopeptide antibiotics related to A54145 by Streptomyces fradiae mutants blocked in biosynthesis of modified amino acids and assignment of lptJ, lptK and lptL gene functions. (English)

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Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/21102596

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Streptomyces fradiae

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HQVCYQAKCXHTHC-BJXXYUDUSA-N

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Unk-Trp-D-Glu-Asn(3-OH)-Thr(1)-Sar-Ala-Asp-D-Lys-Asp-Gly-D-Asn-DL-Glu-xiIle-(1)

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Unk-Trp-D-Glu-Asp-Thr(1)-Sar-Ala-Asp-D-Lys-Asp-Gly-D-Asn-DL-Glu(3-Me)-xiIle-(1)

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Unk-Trp-D-Glu-Asn-Thr(1)-Sar-Ala-Asp-D-Lys-Asp(3-OH)-Gly-D-Asn-DL-Glu-xiIle-(1)

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author name string

Dylan C Alexander

1

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Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/21102596

Jessica Rock

2

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Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/21102596

Jian-Qiao Gu

3

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Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/21102596

Carmela Mascio

4

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/21102596

Min Chu

5

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/21102596

Paul Brian

6

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/21102596

Richard H Baltz

7

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/21102596

publication date

24 November 2010

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Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/21102596

full work available at URL

https://www.nature.com/articles/ja2010138.pdf

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19 March 2024

https://api.unpaywall.org/v2/10.1038/ja.2010.138?email=unpaywall_01@example.com

The Journal of Antibiotics

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Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/21102596

64

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Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/21102596

1

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/21102596

79-87

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Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/21102596

online access status

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19 March 2024

https://api.unpaywall.org/v2/10.1038/ja.2010.138?email=unpaywall_01@example.com

access restriction status

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https://scigraph.springernature.com/pub.10.1038/ja.2010.138

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The safety and efficacy of daptomycin for the treatment of complicated skin and skin-structure infections

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Daptomycin versus standard therapy for bacteremia and endocarditis caused by Staphylococcus aureus

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Effects of prior effective therapy on the efficacy of daptomycin and ceftriaxone for the treatment of community-acquired pneumonia

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Inhibition of daptomycin by pulmonary surfactant: in vitro modeling and clinical impact

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Synthesis and biological activity of N-Acylated ornithine analogues of daptomycin

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Array synthesis of novel lipodepsipeptide

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Genetic engineering in Streptomyces roseosporus to produce hybrid lipopeptide antibiotics

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21 January 2018

Combinatorial biosynthesis of novel antibiotics related to daptomycin

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https://api.crossref.org/works/10.1038%2FJA.2010.138

21 January 2018

The lipopeptide antibiotic A54145 biosynthetic gene cluster from Streptomyces fradiae

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.138

21 January 2018

Development of a genetic system for combinatorial biosynthesis of lipopeptides in Streptomyces fradiae and heterologous expression of the A54145 biosynthesis gene cluster

1 reference

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21 January 2018

Genetically engineered lipopeptide antibiotics related to A54145 and daptomycin with improved properties

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21 January 2018

Stereospecific enzymatic transformation of alpha-ketoglutarate to (2S,3R)-3-methyl glutamate during acidic lipopeptide biosynthesis.

1 reference

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21 January 2018

One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products

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21 January 2018

Integration site for Streptomyces phage phiBT1 and development of site-specific integrating vectors

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.138

21 January 2018

Basic local alignment search tool

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.138

21 January 2018

Structure, biosynthetic origin, and engineered biosynthesis of calcium-dependent antibiotics from Streptomyces coelicolor.

1 reference

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21 January 2018

Mechanistic and structural basis of stereospecific Cbeta-hydroxylation in calcium-dependent antibiotic, a daptomycin-type lipopeptide

1 reference

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21 January 2018

Non-heme hydroxylase engineering for simple enzymatic synthesis of L-threo-hydroxyaspartic acid

1 reference

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21 January 2018

Chemoenzymatic design of acidic lipopeptide hybrids: new insights into the structure-activity relationship of daptomycin and A54145.

1 reference

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21 January 2018

Biosynthesis and genetic engineering of lipopeptide antibiotics related to daptomycin

1 reference

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21 January 2018

A54145, a new lipopeptide antibiotic complex: discovery, taxonomy, fermentation and HPLC.

1 reference

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7 January 2021

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inferred from DOI database lookup

A54145, a new lipopeptide antibiotic complex: isolation and characterization

1 reference

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7 January 2021

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A21978C, a complex of new acidic peptide antibiotics: isolation, chemistry, and mass spectral structure elucidation

1 reference

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7 January 2021

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Enzymatic and chemical modifications of lipopeptide antibiotic A21978C: the synthesis and evaluation of daptomycin (LY146032)

1 reference

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7 January 2021

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A54145, a new lipopeptide antibiotic complex: factor control through precursor directed biosynthesis

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.138

7 January 2021

based on heuristic

inferred from DOI database lookup

Deacylation of A21978C, an acidic lipopeptide antibiotic complex, by Actinoplanes utahensis

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.138

7 January 2021

based on heuristic

inferred from DOI database lookup

A54145, a new lipopeptide antibiotic complex: microbial and chemical modification

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.138

7 January 2021

based on heuristic

inferred from DOI database lookup

A54145 a new lipopeptide antibiotic complex: microbiological evaluation

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.138

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/JA.2010.138

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/21102596

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/21102596

ResearchGate publication ID

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