(Q54401460)

29 May 2018

title

Proteasome inhibition improves the muscle of laminin α2 chain-deficient mice. (English)

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29 May 2018

author name string

Virginie Carmignac

series ordinal

1

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29 May 2018

Ronan Quéré

series ordinal

2

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29 May 2018

Madeleine Durbeej

series ordinal

3

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29 May 2018

publication date

17 November 2010

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29 May 2018

published in

Human Molecular Genetics

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29 May 2018

volume

20

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29 May 2018

issue

3

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29 May 2018

page(s)

541-552

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29 May 2018

Identification of ubiquitin ligases required for skeletal muscle atrophy

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1 reference

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Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

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A protein kinase B-dependent and rapamycin-sensitive pathway controls skeletal muscle growth but not fiber type specification

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Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy

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IKKbeta/NF-kappaB activation causes severe muscle wasting in mice

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Laminin alpha2 chain-null mutant mice by targeted disruption of the Lama2 gene: a new model of merosin (laminin 2)-deficient congenital muscular dystrophy.

21 January 2018

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Schwann cell myelination occurred without basal lamina formation in laminin alpha2 chain-null mutant (dy3K/dy3K) mice

21 January 2018

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21 January 2018

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H36-alpha 7 is a novel integrin alpha chain that is developmentally regulated during skeletal myogenesis

21 January 2018

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Dystrophin glycoprotein complex-associated Gbetagamma subunits activate phosphatidylinositol-3-kinase/Akt signaling in skeletal muscle in a laminin-dependent manner

21 January 2018

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Alpha7beta1-integrin regulates mechanotransduction and prevents skeletal muscle injury

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Inhibition of apoptosis improves outcome in a model of congenital muscular dystrophy

21 January 2018

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Omigapil ameliorates the pathology of muscle dystrophy caused by laminin-alpha2 deficiency

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Proteasome inhibitor (MG-132) treatment of mdx mice rescues the expression and membrane localization of dystrophin and dystrophin-associated proteins

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Pharmacological rescue of the dystrophin-glycoprotein complex in Duchenne and Becker skeletal muscle explants by proteasome inhibitor treatment

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Effect of calpain and proteasome inhibition on Ca2+-dependent proteolysis and muscle histopathology in the mdx mouse

21 January 2018

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Laminin alpha1 chain improves laminin alpha2 chain deficient peripheral neuropathy

21 January 2018

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Laminin alpha1 chain reduces muscular dystrophy in laminin alpha2 chain deficient mice

21 January 2018

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Transgenic overexpression of laminin alpha1 chain in laminin alpha2 chain-deficient mice rescues the disease throughout the lifespan

21 January 2018

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FoxO3 controls autophagy in skeletal muscle in vivo

21 January 2018

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Downstream of Akt: FoxO3 and mTOR in the regulation of autophagy in skeletal muscle

21 January 2018

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PGC-1alpha protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription

21 January 2018

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The activation of Akt/PKB signaling pathway and cell survival.

21 January 2018

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Involvement of Hsp90 in signaling and stability of 3-phosphoinositide-dependent kinase-1.

21 January 2018

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Modulation of Akt kinase activity by binding to Hsp90

21 January 2018

1 reference

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Hsp90 functions to balance the phosphorylation state of Akt during C2C12 myoblast differentiation

21 January 2018

1 reference

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Expression of laminin alpha1, alpha2, alpha4, and alpha5 chains, fibronectin, and tenascin-C in skeletal muscle of dystrophic 129ReJ dy/dy mice.

21 January 2018

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Amelioration of laminin-alpha2-deficient congenital muscular dystrophy by somatic gene transfer of miniagrin

21 January 2018

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Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice

21 January 2018

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An agrin minigene rescues dystrophic symptoms in a mouse model for congenital muscular dystrophy.

21 January 2018

1 reference

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Linker molecules between laminins and dystroglycan ameliorate laminin-alpha2-deficient muscular dystrophy at all disease stages

21 January 2018

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Merosin-deficient congenital muscular dystrophy. Partial genetic correction in two mouse models

21 January 2018

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Pathology is alleviated by doxycycline in a laminin-alpha2-null model of congenital muscular dystrophy

21 January 2018

1 reference

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Inhibition of dystroglycan binding to laminin disrupts the PI3K/AKT pathway and survival signaling in muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ499

Merosin-integrin promotion of skeletal myofiber cell survival: Differentiation state-distinct involvement of p60Fyn tyrosine kinase and p38alpha stress-activated MAP kinase

21 January 2018

1 reference

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Muscle-specific RING finger 1 is a bona fide ubiquitin ligase that degrades cardiac troponin I

21 January 2018

1 reference

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The E3 Ligase MuRF1 degrades myosin heavy chain protein in dexamethasone-treated skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ499

Mechanisms of skeletal muscle atrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ499

Distinct roles for laminin globular domains in laminin alpha1 chain mediated rescue of murine laminin alpha2 chain deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ499

Cardiac ankyrin repeat protein is a marker of skeletal muscle pathological remodelling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ499

21 January 2018

Identifiers

DOI

10.1093/HMG/DDQ499

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29 May 2018

PubMed ID

21084425

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29 May 2018