(Q54465950)

30 May 2018

title

Identification of tyrosine residues critical for the function of an ion-coupled multidrug transporter. (English)

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30 May 2018

author

Shimon Schuldiner

series ordinal

3

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30 May 2018

author name string

Dvir Rotem

series ordinal

1

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30 May 2018

Sonia Steiner-Mordoch

series ordinal

2

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30 May 2018

language of work or name

English

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publication date

3 May 2006

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30 May 2018

Journal of Biological Chemistry

published in

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30 May 2018

volume

281

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30 May 2018

issue

27

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30 May 2018

page(s)

18715-18722

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30 May 2018

A membrane-embedded glutamate is required for ligand binding to the multidrug transporter EmrE

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Bacteriorhodopsin can function without a covalent linkage between retinal and protein.

21 January 2018

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In vitro synthesis of fully functional EmrE, a multidrug transporter, and study of its oligomeric state

21 January 2018

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The Escherichia coli multidrug transporter EmrE is a dimer in the detergent-solubilised state

21 January 2018

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Three-dimensional structure of the bacterial multidrug transporter EmrE shows it is an asymmetric homodimer

21 January 2018

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Exploring the binding domain of EmrE, the smallest multidrug transporter

21 January 2018

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A single carboxyl mutant of the multidrug transporter EmrE is fully functional

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M602088200

An essential glutamyl residue in EmrE, a multidrug antiporter from Escherichia coli

21 January 2018

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A common binding site for substrates and protons in EmrE, an ion-coupled multidrug transporter.

21 January 2018

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A model for coupling of H(+) and substrate fluxes based on "time-sharing" of a common binding site

21 January 2018

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Direct evidence for substrate-induced proton release in detergent-solubilized EmrE, a multidrug transporter.

21 January 2018

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Mystery of multidrug transporters: the answer can be simple

21 January 2018

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Structural biology of bacterial multidrug resistance gene regulators

21 January 2018

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A structure-based mechanism for drug binding by multidrug transporters

21 January 2018

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Crystal structure of bacterial multidrug efflux transporter AcrB

21 January 2018

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Structural Basis of Multiple Drug-Binding Capacity of the AcrB Multidrug Efflux Pump

21 January 2018

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Structural basis of multidrug recognition by BmrR, a transcription activator of a multidrug transporter

21 January 2018

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Cation-pi interactions in chemistry and biology: a new view of benzene, Phe, Tyr, and Trp

21 January 2018

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Substrate-induced tryptophan fluorescence changes in EmrE, the smallest ion-coupled multidrug transporter

21 January 2018

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Mutagenesis of SugE, a small multidrug resistance protein.

21 January 2018

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Characterization of a Na+/H+ antiporter gene of Escherichia coli

21 January 2018

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A bacteriophage T7 RNA polymerase/promoter system for controlled exclusive expression of specific genes

21 January 2018

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Site-directed mutagenesis by overlap extension using the polymerase chain reaction

21 January 2018

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An amino acid cluster around the essential Glu-14 is part of the substrate- and proton-binding domain of EmrE, a multidrug transporter from Escherichia coli.

21 January 2018

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Determining the secondary structure and orientation of EmrE, a multi-drug transporter, indicates a transmembrane four-helix bundle.

21 January 2018

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NMR investigation of the multidrug transporter EmrE, an integral membrane protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602088200

The membrane topology of EmrE - a small multidrug transporter from Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602088200

Functional analysis of novel multidrug transporters from human pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602088200

Negative dominance studies demonstrate the oligomeric structure of EmrE, a multidrug antiporter from Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602088200

Crystal structure of the transcription activator BmrR bound to DNA and a drug

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602088200

Tyrosine residues that control binding and gating in the 5-hydroxytryptamine3 receptor revealed by unnatural amino acid mutagenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602088200

Structure of the substrate binding pocket of the multidrug transporter EmrE: site-directed spin labeling of transmembrane segment 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602088200

Mutations affecting substrate specificity of the Bacillus subtilis multidrug transporter Bmr.

21 January 2018

1 reference

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Crystal structures of QacR-diamidine complexes reveal additional multidrug-binding modes and a novel mechanism of drug charge neutralization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602088200

Structural mechanisms of QacR induction and multidrug recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602088200

Conformational changes in the multidrug transporter EmrE associated with substrate binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602088200

Structure of the multidrug resistance efflux transporter EmrE from Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602088200

RETRACTED: X-ray structure of the EmrE multidrug transporter in complex with a substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602088200

Structural determinants of water permeation through aquaporin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602088200

X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of anion selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602088200

Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602088200

Crosslinking of membrane-embedded cysteines reveals contact points in the EmrE oligomer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602088200

In VitroMonomer Swapping in EmrE, a Multidrug Transporter fromEscherichia coli,Reveals That the Oligomer Is the Functional Unit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602088200

Scanning Cysteine Accessibility of EmrE, an H+-coupled Multidrug Transporter fromEscherichia coli, Reveals a Hydrophobic Pathway for Solutes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602088200

21 January 2018

Identifiers

DOI

10.1074/JBC.M602088200

1 reference

30 May 2018

1 reference

30 May 2018