(Q54472460)

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Enhanced recovery from ischemia-reperfusion injury in PI3Kα dominant negative hearts: investigating the role of alternate PI3K isoforms, increased glucose oxidation and MAPK signaling.

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17 February 2020

Enhanced recovery from ischemia-reperfusion injury in PI3Kα dominant negative hearts: investigating the role of alternate PI3K isoforms, increased glucose oxidation and MAPK signaling (English)

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17 February 2020

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reperfusion injury

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based on heuristic

inferred from title

Petra C Kienesberger

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23142539%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Pavel Zhabyeyev

5

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17 February 2020

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Brent A McLean

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17 February 2020

Wang Wang

3

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17 February 2020

Grant Masson

4

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17 February 2020

Jason R B Dyck

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17 February 2020

Gavin Y Oudit

7

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17 February 2020

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8 November 2012

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17 February 2020

Journal of Molecular and Cellular Cardiology

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17 February 2020

54

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17 February 2020

9-18

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17 February 2020

Myocardial reperfusion injury.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

Left ventricular remodeling after myocardial infarction: pathophysiology and therapy

1 reference

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7 January 2021

The reperfusion injury salvage kinase pathway: a common target for both ischemic preconditioning and postconditioning.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

Phosphorylation of glycogen synthase kinase-3beta during preconditioning through a phosphatidylinositol-3-kinase--dependent pathway is cardioprotective

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

Phosphatidylinositol 3-kinase gamma is a critical mediator of myocardial ischemic and adenosine-mediated preconditioning

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

PI3Kgamma protects from myocardial ischemia and reperfusion injury through a kinase-independent pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

Reperfusion-activated Akt kinase prevents apoptosis in transgenic mouse hearts overexpressing insulin-like growth factor-1

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

New directions for protecting the heart against ischaemia-reperfusion injury: targeting the Reperfusion Injury Salvage Kinase (RISK)-pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

Phosphoinositide 3-kinase(p110α) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

PI3K(p110 alpha) protects against myocardial infarction-induced heart failure: identification of PI3K-regulated miRNA and mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

Cardiac regulation by phosphoinositide 3-kinases and PTEN

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

Protective effects of exercise and phosphoinositide 3-kinase(p110alpha) signaling in dilated and hypertrophic cardiomyopathy

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

Wortmannin and its structural analogue demethoxyviridin inhibit stimulated phospholipase A2 activity in Swiss 3T3 cells. Wortmannin is not a specific inhibitor of phosphatidylinositol 3-kinase.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

Wortmannin, a widely used phosphoinositide 3-kinase inhibitor, also potently inhibits mammalian polo-like kinase.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

Loss of PI3Kγ enhances cAMP-dependent MMP remodeling of the myocardial N-cadherin adhesion complexes and extracellular matrix in response to early biomechanical stress

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

Loss of PTEN attenuates the development of pathological hypertrophy and heart failure in response to biomechanical stress

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

Angiotensin-converting enzyme 2 suppresses pathological hypertrophy, myocardial fibrosis, and cardiac dysfunction.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

Fatty acid translocase/CD36 deficiency does not energetically or functionally compromise hearts before or after ischemia

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

Absence of malonyl coenzyme A decarboxylase in mice increases cardiac glucose oxidation and protects the heart from ischemic injury

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

The role of phosphoinositide-3 kinase and PTEN in cardiovascular physiology and disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

Role of glycogen synthase kinase-3beta in cardioprotection

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

The conserved phosphoinositide 3-kinase pathway determines heart size in mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

PI3Ks maintain the structural integrity of T-tubules in cardiac myocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

The Akt1 isoform is an essential mediator of ischaemic preconditioning

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

The p110beta isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110gamma.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

Synergistic activation of a family of phosphoinositide 3-kinase via G-protein coupled and tyrosine kinase-related receptors

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

Hypoglycaemia, liver necrosis and perinatal death in mice lacking all isoforms of phosphoinositide 3-kinase p85 alpha

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

High levels of fatty acids delay the recovery of intracellular pH and cardiac efficiency in post-ischemic hearts by inhibiting glucose oxidation

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

Myocardial fatty acid metabolism in health and disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

Stimulation of glucose oxidation protects against acute myocardial infarction and reperfusion injury

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

Effects of chronic Akt activation on glucose uptake in the heart

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

A conserved role for phosphatidylinositol 3-kinase but not Akt signaling in mitochondrial adaptations that accompany physiological cardiac hypertrophy.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

AMPK alterations in cardiac physiology and pathology: enemy or ally?

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

AMPK activation, a preventive therapeutic target in the transition from cardiac injury to heart failure

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

High rates of fatty acid oxidation during reperfusion of ischemic hearts are associated with a decrease in malonyl-CoA levels due to an increase in 5'-AMP-activated protein kinase inhibition of acetyl-CoA carboxylase

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

Phosphorylation control of cardiac acetyl-CoA carboxylase by cAMP-dependent protein kinase and 5'-AMP activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.10.015

7 January 2021

AMPK-Mediated AS160 Phosphorylation in Skeletal Muscle Is Dependent on AMPK Catalytic and Regulatory Subunits

1 reference

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7 January 2021

The failing heart--an engine out of fuel

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7 January 2021

Resiliency and vulnerability in the HER2-HER3 tumorigenic driver

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7 January 2021

MEK1-ERK2 signaling pathway protects myocardium from ischemic injury in vivo

1 reference

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7 January 2021

Involvement of extracellular signal-regulated kinases 1/2 in cardiac hypertrophy and cell death

1 reference

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7 January 2021

Role of Mitogen-Activated Protein Kinases in Myocardial Ischemia-Reperfusion Injury during Heart Transplantation

1 reference

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7 January 2021

Activation of p38 mitogen-activated protein kinase abolishes insulin-mediated myocardial protection against ischemia-reperfusion injury

1 reference

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7 January 2021

Targeting the phosphoinositide 3-kinase pathway in cancer

1 reference

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7 January 2021

AKT inhibition relieves feedback suppression of receptor tyrosine kinase expression and activity

1 reference

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7 January 2021

Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer

1 reference

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7 January 2021

Will PI3K pathway inhibitors be effective as single agents in patients with cancer?

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The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins

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7 January 2021

Identifiers

10.1016/J.YJMCC.2012.10.015

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23142539%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23142539%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

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