(Q54481127)

30 May 2018

title

Srs2 helicase of Saccharomyces cerevisiae selectively unwinds triplet repeat DNA. (English)

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30 May 2018

main subject

Saccharomyces cerevisiae

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based on heuristic

inferred from title

author name string

Saumitri Bhattacharyya

series ordinal

1

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30 May 2018

Robert S Lahue

series ordinal

2

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30 May 2018

language of work or name

English

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publication date

4 August 2005

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30 May 2018

Journal of Biological Chemistry

published in

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30 May 2018

volume

280

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30 May 2018

page(s)

33311-33317

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30 May 2018

issue

39

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30 May 2018

Trinucleotide repeats in neurogenetic disorders

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1 reference

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Structural features of trinucleotide repeats associated with DNA expansion

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Trinucleotide repeats that expand in human disease form hairpin structures in vitro

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Inhibition of FEN-1 processing by DNA secondary structure at trinucleotide repeats

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Nuclease-deficient FEN-1 blocks Rad51/BRCA1-mediated repair and causes trinucleotide repeat instability

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Saccharomyces cerevisiae flap endonuclease 1 uses flap equilibration to maintain triplet repeat stability

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Mutations in RAD27 define a potential link between G1 cyclins and DNA replication

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Homologous recombination is required for the viability of rad27 mutants

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Accumulation of single-stranded DNA and destabilization of telomeric repeats in yeast mutant strains carrying a deletion of RAD27.

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Msh2 deficiency prevents in vivo somatic instability of the CAG repeat in Huntington disease transgenic mice

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Trinucleotide expansion in haploid germ cells by gap repair

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Mismatch repair gene Msh2 modifies the timing of early disease in Hdh(Q111) striatum

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CTG repeat instability and size variation timing in DNA repair-deficient mice

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Stability of the human fragile X (CGG)(n) triplet repeat array in Saccharomyces cerevisiae deficient in aspects of DNA metabolism

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Mismatch repair in Escherichia coli enhances instability of (CTG)n triplet repeats from human hereditary diseases

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(CAG)(n)-hairpin DNA binds to Msh2-Msh3 and changes properties of mismatch recognition

21 January 2018

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Saccharomyces cerevisiae Srs2 DNA helicase selectively blocks expansions of trinucleotide repeats.

21 January 2018

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DNA helicase Srs2 disrupts the Rad51 presynaptic filament

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The Srs2 helicase prevents recombination by disrupting Rad51 nucleoprotein filaments.

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21 January 2018

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UvrD helicase, unlike Rep helicase, dismantles RecA nucleoprotein filaments in Escherichia coli.

21 January 2018

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Trinucleotide repeats associated with human disease

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RecQ family helicases: roles in cancer and aging

21 January 2018

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WRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication fork

21 January 2018

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Human Bloom protein stimulates flap endonuclease 1 activity by resolving DNA secondary structure

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21 January 2018

Identifiers

DOI

10.1074/JBC.M503325200

1 reference

30 May 2018

PubMed ID

16085654

1 reference

30 May 2018