(Q54536801)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22238372%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

title

Oxysterols exert proinflammatory effects in placental trophoblasts via TLR4-dependent, cholesterol-sensitive activation of NF-κB (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22238372%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

0 references

0 references

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22238372%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Irving Aye

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22238372%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

author name string

Brendan J Waddell

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22238372%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Peter J Mark

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22238372%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

publication date

10 January 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22238372%20AND%20SRC:MED&resulttype=core&format=json

Molecular Human Reproduction

20 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22238372%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

volume

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22238372%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22238372%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

page(s)

341-353

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22238372%20AND%20SRC:MED&resulttype=core&format=json

Host response to malaria during pregnancy: placental monocyte recruitment is associated with elevated beta chemokine expression

20 January 2020

cites work

1 reference

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Role of adapters in Toll-like receptor signalling

21 January 2018

1 reference

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Placental ABCA1 and ABCG1 transporters efflux cholesterol and protect trophoblasts from oxysterol induced toxicity

21 January 2018

1 reference

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Endogenous ligands of Toll-like receptors: implications for regulating inflammatory and immune responses

21 January 2018

1 reference

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Oxysterols: friends, foes, or just fellow passengers?

21 January 2018

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Protective role of phospholipid oxidation products in endotoxin-induced tissue damage

21 January 2018

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Inhibition of choriodecidual cytokine production and inflammatory gene expression by selective I-kappaB kinase (IKK) inhibitors.

21 January 2018

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Obesity, pregnancy, inflammation, and vascular function.

21 January 2018

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The human placenta in gestational diabetes mellitus. The insulin and cytokine network

21 January 2018

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Endotoxin detection--from limulus amebocyte lysate to recombinant factor C.

21 January 2018

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Effects of oxysterols on cell viability, inflammatory cytokines, VEGF, and reactive oxygen species production on human retinal cells: cytoprotective effects and prevention of VEGF secretion by resveratrol

21 January 2018

1 reference

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Determination of serum 7-ketocholesterol concentrations and their relationships with coronary multiple risks in diabetes mellitus

21 January 2018

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Endogenous ligands of TLR2 and TLR4: agonists or assistants?

21 January 2018

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Oxidized phospholipid inhibition of toll-like receptor (TLR) signaling is restricted to TLR2 and TLR4: roles for CD14, LPS-binding protein, and MD2 as targets for specificity of inhibition

21 January 2018

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Role of nuclear receptors and their ligands in human trophoblast invasion

21 January 2018

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Oxysterol profiles of normal human arteries, fatty streaks and advanced lesions

21 January 2018

1 reference

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Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma

21 January 2018

1 reference

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NF-kappaB and the immune response

21 January 2018

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A novel cyclohexene derivative, ethyl (6R)-6-[N-(2-Chloro-4-fluorophenyl)sulfamoyl]cyclohex-1-ene-1-carboxylate (TAK-242), selectively inhibits toll-like receptor 4-mediated cytokine production through suppression of intracellular signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLEHR%2FGAS001

Measurement of oxysterols and alpha-tocopherol in plasma and tissue samples as indices of oxidant stress status.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLEHR%2FGAS001

TAK-242 selectively suppresses Toll-like receptor 4-signaling mediated by the intracellular domain

21 January 2018

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Pharmacological inhibition of inflammatory pathways for the prevention of preterm birth.

21 January 2018

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Placental cytokines and preeclampsia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLEHR%2FGAS001

Paraoxonase gene polymorphism, serum lipid, and oxidized low-density lipoprotein in preeclampsia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLEHR%2FGAS001

Expression and function of toll-like receptors at the maternal-fetal interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLEHR%2FGAS001

Toll-like receptors at the maternal-fetal interface in normal pregnancy and pregnancy disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLEHR%2FGAS001

Production of interferons and beta-chemokines by placental trophoblasts of HIV-1-infected women

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLEHR%2FGAS001

Proinflammatory effect of cholesterol and its oxidation products on CaCo-2 human enterocyte-like cells: effective protection by epigallocatechin-3-gallate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLEHR%2FGAS001

TAK-242 (resatorvid), a small-molecule inhibitor of Toll-like receptor (TLR) 4 signaling, binds selectively to TLR4 and interferes with interactions between TLR4 and its adaptor molecules.

21 January 2018

1 reference

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Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity

21 January 2018

1 reference

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LXR-activating oxysterols induce the expression of inflammatory markers in endothelial cells through LXR-independent mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLEHR%2FGAS001

Tissue-specific mRNA expression profiles of human toll-like receptors and related genes

21 January 2018

1 reference

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Oxidized phospholipids are more potent antagonists of lipopolysaccharide than inducers of inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLEHR%2FGAS001

Oxysterols: A world to explore.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLEHR%2FGAS001

Lipids from oxidized low-density lipoprotein modulate human trophoblast invasion: involvement of nuclear liver X receptors

21 January 2018

1 reference

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Rafts defined: a report on the Keystone Symposium on Lipid Rafts and Cell Function.

21 January 2018

1 reference

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Attenuation of murine collagen-induced arthritis by a novel, potent, selective small molecule inhibitor of IkappaB Kinase 2, TPCA-1 (2-[(aminocarbonyl)amino]-5-(4-fluorophenyl)-3-thiophenecarboxamide), occurs via reduction of proinflammatory cytokin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLEHR%2FGAS001

Multiplexed flow cytometric analyses of pro- and anti-inflammatory cytokines in the culture media of oxysterol-treated human monocytic cells and in the sera of atherosclerotic patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLEHR%2FGAS001

IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain

21 January 2018

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TLR4 links innate immunity and fatty acid-induced insulin resistance

21 January 2018

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Learning from the placenta: acute atherosis and vascular remodeling in preeclampsia-novel aspects for atherosclerosis and future cardiovascular health

21 January 2018

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Human endothelial cells of the placental barrier efficiently deliver cholesterol to the fetal circulation via ABCA1 and ABCG1.

21 January 2018

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21 January 2018

TLR signaling pathways

1 reference

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Fat and beyond: the diverse biology of PPARgamma

21 January 2018

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Lateral diffusion of Toll-like receptors reveals that they are transiently confined within lipid rafts on the plasma membrane.

21 January 2018

1 reference

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Circulating oxidized low-density lipoprotein and paraoxonase activity in preeclampsia

21 January 2018

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Selective distribution of oxysterols in atherosclerotic lesions and human plasma lipoproteins

21 January 2018

1 reference

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Cytotoxic effects of oxysterols associated with human diseases: Induction of cell death (apoptosis and/or oncosis), oxidative and inflammatory activities, and phospholipidosis.

21 January 2018

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Side effects of oxysterols: cytotoxicity, oxidation, inflammation, and phospholipidosis

21 January 2018

1 reference

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Fatty acids modulate Toll-like receptor 4 activation through regulation of receptor dimerization and recruitment into lipid rafts in a reactive oxygen species-dependent manner

21 January 2018

1 reference

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IKK beta plays an essential role in the phosphorylation of RelA/p65 on serine 536 induced by lipopolysaccharide

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLEHR%2FGAS001

Liver X receptors as integrators of metabolic and inflammatory signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLEHR%2FGAS001

Liver X receptor and retinoid X receptor agonists inhibit inflammatory responses of microglia and astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLEHR%2FGAS001